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Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores
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Synthesis of triazole-linked chloroquinoline derivatives as novel antimalarial agents
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Preclinical pharmacokinetic evaluation of novel antimalarial and antituberculosis drug leads
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Synthesis of 1,4 Dihydropyridines as potential antimalarial chemotype
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Synthesis, physicochemical and biological evaluation of N-dealkylated metabolites of antimalarial pyrido[1,2-a]benzimidazoles and related compounds containing a Mannich base side-chain
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Structure and synthesis of some phosphorus compounds of potential biological activity
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Antimalarial benzimidazoles and related structures incorporating an intramolecular hydrogen bonding motif: medicinal chemistry and mechanistic studies
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Antimalarial and cysteine protease inhibitor pharmacophores as scaffolds for new antimalarial agents
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Haematin-Quinoline interactions and structure-activity relationships in the antimalarial chloroquine and related compounds
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In Silico Pharmacokinetic Profile and Antimalarial Efficacy of 3-Chloro-4-(4-Chlorophenoxy)Aniline
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Bioactive chloroquine-based ligands and their gold complexes as potential novel antimalarial agents
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Synthesis and investigation of quinoline based ß-haematin formation inhibitors as potential antimalarials
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Synthesis and mechanistic studies into the cytotoxic activity of garlic-related trisulfides in cancer cells
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Studies on the synthesis, cyclodextrin inclusion and biological activity of ajoene analogues as potentially novel anti-cancer agents
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Novel Antimalarial and Antitubercular Agents Based on Natural Products
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Synthesis, antimalarial evaluation, Ç-hematin inhibition, and in silico and in vitro ADMET profiling of 4-aminoquinoline-hydroxypyridinone hybrids
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Elaboration of 4′-Phosphopantetheine Adenylyltransferase inhibitors and Benzoxaboroles as antimalarial agents
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Design and synthesis of novel antimalarial agents
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The potential of anti-malarial compounds derived from African medicinal plants, part III: an evaluation of drug metabolism and pharmacokinetics profiling
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Single and hybrid antimalarials based on artemisinin, chloroquine and ß-lactams : synthesis, antiplasmodial activity, cytotoxicity and effect of selected artemisinin-chloroquine hybrids on the parasitic endocytosis pathway
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Mechanistic insights into the cancer cell cytotoxicity and blood stability of the garlic compound ajoene
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The characterization of pharmacokinetic properties and evaluation of in vitro drug combination efficacies of novel antimalarial compounds
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Performance Assessment of Chitosan-Surfactin Nanocomplex for pH-stimulated Potential Oral Delivery of Curcumin
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Synthesis, structure-activity relationship and solubility improvement studies of potential antimalarial and antischistosomal pyrido[1,2-a]benzimidazoles
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Synthesis and biological evaluation of thiazole and metergoline derivatives as antimycobacterial and antiplasmodial agents
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Synthesis, structure-activity relationship and solubility improvement studies of potential antimalarial and antischistosomal pyrido[1,2-a]benzimidazoles
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Small molecule inhibitors of parasitic enzymes
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Antiplasmodial neolignans from Trema orientalis : identification, synthesis and analogue generation.
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Synthesis, pharmacological and physicochemical profiling of antimalarial and antischistosomal N-aryl 3-trifluoromethyl pyrido [1,2-α] benzimidazoles
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Design, synthesis and evaluation of potential dual drugs targeting the haemoglobin degradation pathway in the malaria parasite Plasmodium falciparum
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Synthesis and profiling of antimalarial side-chain modified pyrido[1,2-a]benzimidazoles
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Synthesis of aminomethylthiazole analogues for evaluation as antiplasmodial agents
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Synthesis and Antimalarial evaluation of Gold Thiosemicarbazone Complexes and Polyamine-Thiosemicarbazone Dendrimers
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Repurposing chlorpromazine and its metabolites for antituberculosis drug discovery
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A medicinal chemistry approach to drug repositioning in the treatment of tuberculosis and malaria
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Repositioning fusidic acid for tuberculosis: semi-synthesis of analogues and impact of mycobacterial biotransformation on antibiotic activity
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Antiprotozoal quinolines containing electrophilic moieties
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Novel Antimalarial and Antitubercular Agents Based on Natural Products
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Isolation and characterization of African marine natural products and repositioning of the natural product antibiotic fusidic acid and privileged benzimidazole scaffold for tuberculosis and malaria
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Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores
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Exploring the potential of xanthene derivatives as inhibitors of trypanothione reductase and resistance reversal agents
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Investigating the chemical space and metabolic bioactivation of natural products and cross-reactivity of chemical inhibitors in CYP450 phenotyping
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Ferrocenic metal chelators : synthesis, biological and electrochemical studies
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Piperazine-based pyrido[1,2-a]benzimidazoles: synthesis and pharmacological evaluation as potential antimalarial and antischistosomal agents
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Bioactive chloroquine-based ligands and their gold complexes as potential novel antimalarial agents
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Synthesis and evaluation of D-cycloserine analogues against mycobacterium tuberculosis
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Antimalarial drug rescue through safety improvement: design, synthesis and evaluation of amaodiaquine analogues
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Developing methods to prioritize in vitro drug combinations against Mycobacterium tuberculosis: fusidic acid as potential combination partner with known antitubercular agents
