Channels Repositioning fusidic acid for tuberculosis: semi-synthesis of analogues and impact of mycobacterial biotransformation on antibiotic activity
Synthesis and biological evaluation of thiazole and metergoline derivatives as antimycobacterial and antiplasmodial agents
Synthesis, structure-activity relationship and solubility improvement studies of potential antimalarial and antischistosomal pyrido[1,2-a]benzimidazoles
Small molecule inhibitors of parasitic enzymes
Antiplasmodial neolignans from Trema orientalis : identification, synthesis and analogue generation.
Synthesis, pharmacological and physicochemical profiling of antimalarial and antischistosomal N-aryl 3-trifluoromethyl pyrido [1,2-α] benzimidazoles
Design, synthesis and evaluation of potential dual drugs targeting the haemoglobin degradation pathway in the malaria parasite Plasmodium falciparum
Synthesis and profiling of antimalarial side-chain modified pyrido[1,2-a]benzimidazoles
Synthesis of aminomethylthiazole analogues for evaluation as antiplasmodial agents
Synthesis and Antimalarial evaluation of Gold Thiosemicarbazone Complexes and Polyamine-Thiosemicarbazone Dendrimers
Repurposing chlorpromazine and its metabolites for antituberculosis drug discovery
A medicinal chemistry approach to drug repositioning in the treatment of tuberculosis and malaria
Repositioning fusidic acid for tuberculosis: semi-synthesis of analogues and impact of mycobacterial biotransformation on antibiotic activity
Antiprotozoal quinolines containing electrophilic moieties
Novel Antimalarial and Antitubercular Agents Based on Natural Products
Isolation and characterization of African marine natural products and repositioning of the natural product antibiotic fusidic acid and privileged benzimidazole scaffold for tuberculosis and malaria
Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores
Exploring the potential of xanthene derivatives as inhibitors of trypanothione reductase and resistance reversal agents
Investigating the chemical space and metabolic bioactivation of natural products and cross-reactivity of chemical inhibitors in CYP450 phenotyping
Ferrocenic metal chelators : synthesis, biological and electrochemical studies
Piperazine-based pyrido[1,2-a]benzimidazoles: synthesis and pharmacological evaluation as potential antimalarial and antischistosomal agents
Bioactive chloroquine-based ligands and their gold complexes as potential novel antimalarial agents
Synthesis and evaluation of D-cycloserine analogues against mycobacterium tuberculosis
Antimalarial drug rescue through safety improvement: design, synthesis and evaluation of amaodiaquine analogues
Developing methods to prioritize in vitro drug combinations against Mycobacterium tuberculosis: fusidic acid as potential combination partner with known antitubercular agents
