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Antimalarial benzimidazoles and related structures incorporating an intramolecular hydrogen bonding motif: medicinal chemistry and mechanistic studies
Recent Advances in Intramolecular C─N Bond Formation for Pyrrolidine Synthesis
Synthesis and profiling of antimalarial side-chain modified pyrido[1,2-a]benzimidazoles
Synthesis and investigation of benzimidazole and carbazole ß-haematin inhibiting scaffolds with antimalarial activity
Intramolecular Diels-Alder reactions of conformationally restricted systems
Synthesis, structure-activity relationship and solubility improvement studies of potential antimalarial and antischistosomal pyrido[1,2-a]benzimidazoles
Synthesis, pharmacological and physicochemical profiling of antimalarial and antischistosomal N-aryl 3-trifluoromethyl pyrido [1,2-α] benzimidazoles
Hydrogen bond potentials for some HCN and HNC complexes
Synthesis, physicochemical and biological evaluation of N-dealkylated metabolites of antimalarial pyrido[1,2-a]benzimidazoles and related compounds containing a Mannich base side-chain
Phytochemical studies on traditional medicinal plants with antimalarial activities
Curcumin-related hybrid compounds as potential antimalarial agents : design, synthesis, mechanistic investigations, biological evaluation and pharmacokinetic studies
Structure-activity and structure-property relationships of antimalarial pyrimido[1,2-a]benzimidazoles, imidazo[1,2-a]pyridines, and imidazo[1,2-a]pyrimidines
Utilisation of various bonding modes of nitrogen-rich heterocycles in gold(I) chemistry
The synthesis and evaluation of new organometallic benzimidazole Complexes as antiplasmodials
A medicinal chemistry approach to drug repositioning in the treatment of tuberculosis and malaria
Synthesis and biological evaluation of benzimidazole-linked 1,2,3-triazole congeners as agents
Synthesis and biological evaluation of trimeric 2,5-disubstituted benzimidazoles and related trinuclear ruthenium(II) organometallic complexes
Antimalarial and cysteine protease inhibitor pharmacophores as scaffolds for new antimalarial agents
Medicinal Plant-Derived Bioinspired Carbon Quantum Dots: From Precursor Chemistry to Precision Cancer Theranostics
Synthesis, biological activity and physicochemical properties evaluation of antiplasmodial pyrimido[1,2-a]benzimidazoles
Theoretical investigation of CH,HC contacts and other intramolecular interactions in 2,2′-Bipyridine and itscomplexes with metal ions
Development of aminoquinoline-benzimidazole hybrids and their organometallic complexes as antimicrobial agents against Plasmodium falciparum and Mycobacterium tuberculosis
Physicochemical, biological and β-haematin inhibiting activity of pyrido-dibemequines, pyrido[1,2-α]benzimidazoles and their derivatives
Platinum group metal coordination complexes of ferrocenyl N-donor ligands and their potential application in catalysis and medicinal chemistry
Antimalarials based on the arylpiperazine privileged substructure
Synthesis and biological evaluation of thiazole and metergoline derivatives as antimycobacterial and antiplasmodial agents
Synthesis, structure-activity relationship and solubility improvement studies of potential antimalarial and antischistosomal pyrido[1,2-a]benzimidazoles
Small molecule inhibitors of parasitic enzymes
Antiplasmodial neolignans from Trema orientalis : identification, synthesis and analogue generation.
Synthesis, pharmacological and physicochemical profiling of antimalarial and antischistosomal N-aryl 3-trifluoromethyl pyrido [1,2-α] benzimidazoles
Design, synthesis and evaluation of potential dual drugs targeting the haemoglobin degradation pathway in the malaria parasite Plasmodium falciparum
Synthesis and profiling of antimalarial side-chain modified pyrido[1,2-a]benzimidazoles
Synthesis of aminomethylthiazole analogues for evaluation as antiplasmodial agents
Synthesis and Antimalarial evaluation of Gold Thiosemicarbazone Complexes and Polyamine-Thiosemicarbazone Dendrimers
Repurposing chlorpromazine and its metabolites for antituberculosis drug discovery
A medicinal chemistry approach to drug repositioning in the treatment of tuberculosis and malaria
Repositioning fusidic acid for tuberculosis: semi-synthesis of analogues and impact of mycobacterial biotransformation on antibiotic activity
Antiprotozoal quinolines containing electrophilic moieties
Novel Antimalarial and Antitubercular Agents Based on Natural Products
Isolation and characterization of African marine natural products and repositioning of the natural product antibiotic fusidic acid and privileged benzimidazole scaffold for tuberculosis and malaria
Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores
Exploring the potential of xanthene derivatives as inhibitors of trypanothione reductase and resistance reversal agents
Investigating the chemical space and metabolic bioactivation of natural products and cross-reactivity of chemical inhibitors in CYP450 phenotyping
Ferrocenic metal chelators : synthesis, biological and electrochemical studies
Piperazine-based pyrido[1,2-a]benzimidazoles: synthesis and pharmacological evaluation as potential antimalarial and antischistosomal agents
Bioactive chloroquine-based ligands and their gold complexes as potential novel antimalarial agents
Synthesis and evaluation of D-cycloserine analogues against mycobacterium tuberculosis
Antimalarial drug rescue through safety improvement: design, synthesis and evaluation of amaodiaquine analogues
Developing methods to prioritize in vitro drug combinations against Mycobacterium tuberculosis: fusidic acid as potential combination partner with known antitubercular agents