-
In silico prediction of host-pathogen protein - protein interactions in the malaria parasite, Plasmodium falciparum
-
Structure-based inhibitor design and validation : application to Plasmodium falciparum glutathione S-transferase
-
Antiplasmodial- and chloroquine resistance reversal properties of a new diterpene from Croton steenkampianus
-
Molecular modeling elucidates parasite-specific features of polyamine pathway enzymes of Plasmodium falciparus
-
Functional genomics analysis of the effects of co-inhibition of the malarial S-adenosylmethionine decarboxylase/ornithine decarboxylase
-
Mathematical modelling on interaction between malaria parasites and the host immune system
-
High-content and super-resolution microscopy reveals the dynamic nuclear architecture and mobile epigenetic marks in Plasmodium falciparum
-
Functional consequences of the inhibition of Malaria S-adenosylmethionine decarboxylase as a key regulator of polyamine and methionine metabolism
-
Investigation of Coenzyme A levels in Plasmodium falciparum to ascertain the mode of action of new antimalarial candidates
-
Biochemical characterisation of putrescine and spermidine uptake as a potential therapeutic target against the human malaria parasite, Plasmodium falciparum
-
Metabolomic analyses of the malaria parasite after inhibition of polyamine biosynthesis
-
Structural and electronic features of tungsten(0) and platinum(II) complexes with Fischer carbene ligands
-
Synthesis and evaluation of pantothenic acid analogues as potential inhibitors of malaria parasites and bacteria
-
Molecular characterisation of the ornithine decarboxylase gene of the human malaria parasite, plasmidium falciparum
-
Modelling of the invasion dynamics of plasmodium falciparum merozoites into red blood cells
-
Synthesis of mixed ligand, water soluble square planar platinum (II) complexes and an investigation of their association with haematin and potential to inhibit the formation of synthetic malaria pigment
-
Discovery and radiopharmaceutical development of probes for prospective positron emission tomography imaging of malaria
-
Deconvoluting drug mode-of-action : transcriptomic evaluation of novel clinical lead antimalarials
-
Target indicators and mechanistic function of epidrugs with activity against multiple stages of Plasmodium falciparum parasites
-
Spatial and temporal distribution of a marine microbial parasite, Syndiniales MALV I and II, within St Helena Bay
-
Platinum (II) complexes of heteroaromatic derivatives
-
A multinuclear (1H, 13C, 31P and 195Pt) magnetic resonance spectroscopy study of mixed ligand platinum(II) complexes with new N,N-dialkyl-N'-acyl(aroyl)thioureas as ligands
-
A study of cis-trans isomerisation of the bis-chelated complexes of platinum (II) and palladium (II) with N,N-dialkyl-N'aroyl(acyl)thiourea ligands
-
Comparative immune-profiling of tick vaccine formulations and the role of co-infestation with Babesia microti in Ixodes ricinus-infested BALB/c mice
-
Synthesis and biological evaluation of thiazole and metergoline derivatives as antimycobacterial and antiplasmodial agents
-
Synthesis, structure-activity relationship and solubility improvement studies of potential antimalarial and antischistosomal pyrido[1,2-a]benzimidazoles
-
Small molecule inhibitors of parasitic enzymes
-
Antiplasmodial neolignans from Trema orientalis : identification, synthesis and analogue generation.
-
Synthesis, pharmacological and physicochemical profiling of antimalarial and antischistosomal N-aryl 3-trifluoromethyl pyrido [1,2-α] benzimidazoles
-
Design, synthesis and evaluation of potential dual drugs targeting the haemoglobin degradation pathway in the malaria parasite Plasmodium falciparum
-
Synthesis and profiling of antimalarial side-chain modified pyrido[1,2-a]benzimidazoles
-
Synthesis of aminomethylthiazole analogues for evaluation as antiplasmodial agents
-
Synthesis and Antimalarial evaluation of Gold Thiosemicarbazone Complexes and Polyamine-Thiosemicarbazone Dendrimers
-
Repurposing chlorpromazine and its metabolites for antituberculosis drug discovery
-
A medicinal chemistry approach to drug repositioning in the treatment of tuberculosis and malaria
-
Repositioning fusidic acid for tuberculosis: semi-synthesis of analogues and impact of mycobacterial biotransformation on antibiotic activity
-
Antiprotozoal quinolines containing electrophilic moieties
-
Novel Antimalarial and Antitubercular Agents Based on Natural Products
-
Isolation and characterization of African marine natural products and repositioning of the natural product antibiotic fusidic acid and privileged benzimidazole scaffold for tuberculosis and malaria
-
Synthesis and evaluation of hybrid compounds based on antimalarial and anticancer pharmacophores
-
Exploring the potential of xanthene derivatives as inhibitors of trypanothione reductase and resistance reversal agents
-
Investigating the chemical space and metabolic bioactivation of natural products and cross-reactivity of chemical inhibitors in CYP450 phenotyping
-
Ferrocenic metal chelators : synthesis, biological and electrochemical studies
-
Piperazine-based pyrido[1,2-a]benzimidazoles: synthesis and pharmacological evaluation as potential antimalarial and antischistosomal agents
-
Bioactive chloroquine-based ligands and their gold complexes as potential novel antimalarial agents
-
Synthesis and evaluation of D-cycloserine analogues against mycobacterium tuberculosis
-
Antimalarial drug rescue through safety improvement: design, synthesis and evaluation of amaodiaquine analogues
-
Developing methods to prioritize in vitro drug combinations against Mycobacterium tuberculosis: fusidic acid as potential combination partner with known antitubercular agents
