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Pharmacogenetics of CYP2D6 and CYP2C19 as a pre-prescription tool for drug efficacy and toxicity in a demographically-representative sample of theSouth African population
Detection of sequence diversity in the CYP2C19 gene of Xhosa South African individuals : an analytical and comparative study including in silico and functional analysis of the 5’ flanking region
Pharmacokinetic-Pharmacogenetic-and-Pharmacodynamic Adherence Relationships in Cohort South African HIV Infected Children on Lopinavir-and Nevirapine-Based Regimens
Pharmacogenetics of resistant hypertension: evaluating the role of genetic variation in ABCB1, ADBR1, CES1, CYP3A4, CYP3A5, NEDD4L, NOS3, NR3C2 and SCNN1B among South African hypertensive patient
Prevalence of genetic polymorphisms associated with anti-cancer drug efficacy and toxicity in the South African population
The influence of dual CYP17 expression on adrenal steroidogenesis in the South African Angora Goat
Characterising select hepatocyte cultures for improved hepatotoxicity testing
Development of an in vitro mechanistic toxicity screening model using cultured hepatocytes
Investigation of genetic variation contributing to antipsychotic treatment response in a South African first episode schizophrenia cohort
Investigating the role of miRNA-mediated regulation in antipsychotic treatment response in a South African first-episode schizophrenia cohort
Development and evaluation of an alkane bioconversion process using genetically modified Escherichia coli
Investigating the functional significance of genome-wide variants associated with antipsychotic treatment response in schizophrenia
Molecular genetic analyses of antipsychotic pharmacogenes in a South African first episode schizophrenia cohort
Inhibitory effect of selected herbal supplements on CYP450-mediated metabolism : an in vitro approach
Development and application of a pathology supported pharmacogenetic test for improved clinical management of South African patients with breast cancer and associated co-morbidities
Associations of CYP2B6, CYP2C19, and CYP2D6 isoforms and phenoconversion with sertraline pharmacokinetics
The determination and validation of population pharmacokinetic parameters of phenytoin in adult epileptic patients in the Western Cape using nonlinear mixed-effects modelling
Effects of environmental temperature on pharmacokinetics of, and clinical response to xylazine in goats
Molecular genetic analysis of human immunodeficiency virus antiretroviral therapy response in South Africa : a pharmacogenetics study
In vitro assessment of some traditional medications used in South Africa for pharmacokinetics drug interaction potential
First principles studies of Si-C alloys
The bio-conjugation of Cytochalasin B
Phenotypic characterization of B cells and serum cytokine responses during Tuberculosis and Type 2 Diabetes
Comparative pharmacokinetics of a single and double dose of a conventional oxytetracycline formulation in sheep, to allow for therapeutic optimisation
In vitro Modulation of Cytochrome P450 Isozymes and Pharmacokinetics of Caffeine by Extracts of Hibiscus sabdariffa Linn Calyx.