Channels Influence of previous tuberculosis treatment on time to culture conversion for patients receiving a bedaquiline-containing regimen at Sizwe Tropical Disease Hospital, South Africa
Overexpression of mmpS5/mmpL5 in Mycobacterium tuberculosis reduces susceptibility to anti-tuberculosis drugs
Resistance to new tuberculosis drugs
Sodium, potassium adenosine triphosphatase as a potential target of the anti-tuberculosis agents, clofazimine and bedaquiline
Novel and rapid tests for diagnosis of tuberculosis using non-sputum specimens
Addressing critical knowledge gaps to improve and shorten multidrug-resistant tuberculosis treatment regimens in children
Transmission of bedaquiline-resistant tuberculosis in the Western Cape Province, South Africa
Mathematical modelling to project the impact of interventions targeted to previously treated individuals on the trajectory of the tuberculosis epidemic in high tuberculosis prevalence settings
A pharmacometric approach to optimal use of second line drugs for multidrug-resistant tuberculosis
The carriage of antimicrobial resistance genes in children from Cape Town communities.
Novel approaches for the diagnosis of drug-resistance, treatment response, and infectiousness in patients with tuberculosis (the eDIToR study – Diagnosis Infectiousness and Treatment Response)
Evaluation of rapid low-cost colorimetric methods for diagnosis of multidrug-resistant tuberculosis in limited-resource settings
Accuracy and impact of the MTBDRplus v2 and MTBDRsl v2 line probe assays for the detection of first-line and second-line drug resistant tuberculosis
Distortion product otoacoustic emissions: towards reliable and valid early identification and monitoring of hearing in adults receiving ototoxic medication
Development of a drug discovery protocol through the expression of key mycothiol biosynthetic enzymes for Mycobacterium tuberculosis
Mechanisms of resistance to new generation anti-TB drugs
Characterisation of phenotypic and genotypic resistance to new and re-purposed tuberculosis drugs in the Western Cape, South Africa
Investigating the relationship between plasma and intracellular concentrations of bedaquiline and its metabolite N-desmethyl bedaquiline (M2) in drug resistant-TB patients with and without HIV infection in South Africa
Deciphering the physiology of drug tolerant and resistant Mycobacterium tuberculosis
Defining the role of efflux pump inhibitors on anti-TB drugs in Rifampicin resistant clinical Mycobacterium Tuberculosis isolates
Immunological markers for active TB and early treatment response indicators
Assessment, diagnosis and management of pulmonary tuberculosis in children under five years of age in the Langeberg sub-district, Western Cape, South Africa
Molecular detection of Mycobacterium tuberculosis in stool of children with suspected intrathoracic tuberculosis
Diagnostic accuracy of novel sputum and non-sputum-based tuberculosis diagnostics in HIV-positive patients initiating anti-retroviral therapy
Determination of the pathogenetic mechanisms for, and the diagnostic implications of, raised adenosine deaminase (ADA) levels in tuberculous exudates
