Channels :: FRELIP Discovery

Author: De Vos, Margaretha

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Targeted deep sequencing to detect heterogeneity in Mycobacterium tuberculosis populations

Similar Items: Targeted deep sequencing to detect heterogeneity in Mycobacterium tuberculosis populations

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Investigating the host-directed therapeutic potential of curdlan-functionalised PLGA nanoparticles in the treatment of intracellular Mycobacterium tuberculosis
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Characterizing mycobacterium tuberculosis persister populations.
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Defining mechanisms that determine the levels of drug resistance in Mycobacterium tuberculosis
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Pyrazinamide resistance in Mycobacterium tuberculosis
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Resistance to the novel nitroimidazole drug class in Mycobacterium tuberculosis
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Deciphering the impact of rpoB mutations on the gene expression profile of Mycobacterium tuberculosis
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Deciphering the mechanisms of Isoniazid reisistance to mycobacterium tuberculosis
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Genetic characterization of drug resistant clinical isolates of Mycobacterium tuberculosis circulating within the Copperbelt province and Northern regions of Zambia.
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Defining the role of efflux pump inhibitors on anti-TB drugs in Rifampicin resistant clinical Mycobacterium Tuberculosis isolates
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Evolution of XDR-TB and the associated proteome
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Characterisation of phenotypic and genotypic resistance to new and re-purposed tuberculosis drugs in the Western Cape, South Africa
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New and improved methods for the diagnosis of susceptibility to tuberculosis drugs
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Clinically relevant mutations contributing to drug resistance in Mycobacterium tuberculosis
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Deciphering the physiology of drug tolerant and resistant Mycobacterium tuberculosis
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Design, synthesis and biological evaluation of verapamil analogues, reversed isoniazids and hybrid efflux pump inhibitors against Mycobacterium tuberculosis
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The effect of environmental conditions on growth and phenotype switching in Mycobacterium smegmatis
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Improving methods for genotypic drug resistance testing in Mycobacterium tuberculosis
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Mathematical modelling of cholesterol metabolism in Mycobacterium tuberculosis
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Molecular characterization and drug susceptibility of isolates from MDR-TB patients in the Eastern Cape and North West provinces of South Africa
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Investigation of the Genetic Basis of Antibiotic Resistance in Mycobacterium tuberculosis
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Regulation of efflux in rifampicin resistant mutants of Mycobacterium tuberculosis
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Advancing the understanding of the PE/PPE protein families through PPE_MPTR protein expression and analysis of pe/ppe single nucleotide variants in differentially drug sensitive Mycobacterium tuberculosis.
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Investigating permeation of anti-mycobacterial agents in Mycobacterium tuberculosis and M. tuberculosis-infected macrophages in vitro as a model for early stage tuberculosis drug discovery
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The influence of small RNAs on the physiology of Mycobacterium tuberculosis