Channels :: FRELIP Discovery

Author: Khonde,Lutete Peguy

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Synthesis of Mycobacterial Ergothioneine biosynthetic pathway metabolites

Author: Manuel, Gaynor

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Synthesis and evaluation of flouro and thia lipids as bioanalytical tools

Similar Items: Synthesis and evaluation of M.tb Glycosyltransferase (MshA) inhibitors

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Stereoselective synthesis 2-C-alkylglucosides, potential inhibitors of mycobacterial MshB and related enzymes
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Rationalising the inhibition of M. tuberculosis MshB by a series of inhibitors constructed from plumbagin conjugated via a viariable alkyl linker to a phenyl thioglycoside
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Characterisation of a public T cell clonotype enriched in m.tb infected individuals who do not progress to tuberculosis
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Transcriptional regulation of glycosyltransferase genes in MCF-7 human breast cancer cell line following drug treatment
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Characterization of human alveolar macrophages and blood monocyte-derived macrophages responses to M.tb in TB close contacts with and without type 2 diabetes
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The role of mucosal-associated invariant T (MAIT) cells in long-term resistance to Mycobacterium tuberculosis (M.tb) infection in healthcare workers with sustained occupational exposure to TB
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Strengthening mechanism of different morphologies of nano-sized MSH on tribological performance of phosphate/MoS bonded solid lubricating coatings
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Synthesis and biological evaluation of antiparasitic Cysteine protease inhibitors based on the Isatin Scaffold
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Evaluating the impact of an Xpert® MTB/RIF- based TB diagnostic algorithm in a routine operational setting in Cape Town
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Synthesis of analogues of mycothiol as possible inhibitors of enzymes in the biosynthesis of mycothiol
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Synthesis of side-chain-modified mycothiol analogues incorporating carbazole quinones, and evaluation as inhibitors of enzymes in the Mycobacteria
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The synthesis of novel kinase inhibitors using click chemistry
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Design and synthesis of potential inhibitors of enzymes involved in the biosynthesis and utilisation of mycothiol
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Synthesis and investigation of quinoline based ß-haematin formation inhibitors as potential antimalarials
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Erratum to: Design and synthesis of tetrahydrophthalimide derivatives as inhibitors of HIV-1 reverse transcriptase
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Erratum to: Design and synthesis of tetrahydrophthalimide derivatives as inhibitors of HIV-1 reverse transcriptase
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Structure-guided screening of bioactive phytoconstituents as prospective inhibitors of SARS-CoV-2 M
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The rational design and synthesis of novel HIV non-nucleoside reverse transcriptase inhibitors
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The design and synthesis of potential acetylcholinesterase inhibitors and NMDA antagonists as neuroprotective agents
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Scaffold manipulation for the synthesis of novel, potentially irreversible Akt inhibitors
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The synthesis of analogues and bioisosteres of the acetylcholinesterase inhibitor donepezil in an attempt to identify novel anti-Alzheimer’s agents
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Development of new methodologies for functionalizing glycals and 1,2-cyclopropanated sugars, and applications in the synthesis of inhibitors of enzymes in the Mycobacteria
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Attempted routes towards the synthesis of fluorinated analogues of ornithine as potential inhibitors of ornithine decarboxylase
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Design, synthesis and biological evaluation of verapamil analogues, reversed isoniazids and hybrid efflux pump inhibitors against Mycobacterium tuberculosis

Similar Items: Synthesis and evaluation of flouro and thia lipids as bioanalytical tools