Channels :: FRELIP Discovery

Author: Mashabela, Gabriel Tshwahla

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Targeting MEP pathway for the development of antitubercular drugs

Similar Items: Targeting MEP pathway for the development of antitubercular drugs

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Effect of oxidative stress on MEP pathway dependent enzyme and cytokinin production in Mycobacteria
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Metallophiles as sources of antimycobacterial agents
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Towards the diagnosis of two intracellular pathogens of grapevine in South Africa
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Regulatory responses to rifampicin exposure in Mycobacterium tuberculosis
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An analytical investigation of the impact of crushing of first-line antituberculosis medication and administration via a nasogastric tube
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Investigating the expression of the CRISPR-associated Cas genes in Mycobacterium tuberculosis under antibiotic stress
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Determination of the mechanism of synergy of SQ109 with rifampicin and isoniazid in Mycobacterium smegmatis
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Investigation of the expression and immunogenicity of Mycobacterium tuberculosis Rv1460
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Characterisation of secondary metabolite pathways in the Ceratocystidaceae
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De novo assembly of admixed South African genomes and its application in genetic susceptibility to tuberculosis.
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A critical interrogation of the acceptability of antituberculosis treatment in caregivers, children, and adolescents in the Western Cape, South Africa
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The pharmacokinetics and toxicity of antituberculosis agents and other co-administered drugs in children with tuberculosis, with and without HIV infection, and their relationship to nutritional status
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Pharmacokinetics and safety of first -- and second--line anti-- tuberculosis drugs in children
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Elucidating the Smurf1- and other E3 ligase-mediated ubiquitination of mycobacterial proteins
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Validation of the MEP pathway’s [Fe-S] cluster enzymes as drug targets in mycobacteria
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The identification of novel proteins involved in iron-sulphur cluster biogenesis in mycobacteria
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Development of a drug discovery protocol through the expression of key mycothiol biosynthetic enzymes for Mycobacterium tuberculosis
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Sputum derived biomarkers of anti-tuberculosis drug activity in early bactericidal activity (EBA) studies
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Employing omics to investigate the macrophage response to infection with pathogenic and non-pathogenic mycobacteria
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Special trends and factors affecting tuberculosis in South Africa (2004-2014) : Evidence from the vital registration systems
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Overexpression of mmpS5/mmpL5 in Mycobacterium tuberculosis reduces susceptibility to anti-tuberculosis drugs
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Care pathway for the newly diagnosed patients living with HIV/PTB co-infection in South Africa
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Exploring the gut microbiome of children from Cape Town communities
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The development of a method to evaluate the use and medical and socioeconomic implications of antihypertensive drug treatment in the Mamre community