Channels :: FRELIP Discovery

Author: Mashabela, Gabriel

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CRISPR interference screening model organisms for TB drugs development.

Similar Items: CRISPR interference screening model organisms for TB drugs development.

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CRISPRi mediated investigation of the vulnerability of two essential cell wall biosynthetic gene products in mycobacteria.
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CRISPR-based genome editing tools for virus resistance in grapevine
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Mechanisms of resistance to new generation anti-TB drugs
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Evaluating TB treatment responses by [18F]FDG-PET/CT imaging
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Assessing the role of the KISS1 receptor in breast cancer cell behaviour with the use of CRISPR-mediated gene editing
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Effect of oxidative stress on MEP pathway dependent enzyme and cytokinin production in Mycobacteria
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Molecular characterization and drug susceptibility of isolates from MDR-TB patients in the Eastern Cape and North West provinces of South Africa
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Evaluation of a radiometrically-determined regrowth model for the study of anti-tuberculosis drugs
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Probing the Mycobacterial Cell Envelope: CRISPR interference-mediated investigation of two essential genes in the galactan biosynthetic pathway
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Targeted depletion of RibF, a putative bifunctional FAD synthetase/ flavokinase in Mycobacterium smegmatis using CRISPR interference
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Pro–apoptotic iron oxide nanosystems as selective anti – TB drugs
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Extensively drug-resistant tuberculosis in Africa: prevalence and factors associated: a systematic review and meta-analysis
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Efficacy and safety of novel and repurposed drugs for the treatment of drug-resistant tuberculosis
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Mycobacterium tuberculosis, a major threat to health in South Africa : intracellular survival after treatment with novel drugs designed against the mycothiol pathway
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Defining the role of efflux pump inhibitors on anti-TB drugs in Rifampicin resistant clinical Mycobacterium Tuberculosis isolates
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The in vitro anti-mycobacterial activities of the novel tetramethylpiperidyl-substituted phenazines, B4121 and B4128
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The carriage of antibiotic resistant Gram-negative organisms in children in the Cape Town community and the impact of antibiotic exposure on the development of resistance (a TB-CHAMP sub-study)
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The use of aminoglycoside antibiotic therapy in neutropaenic patients with haematological disease
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Characterization of the innate and adaptive immune systems during active TB disease and during treatment
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Investigating permeation of anti-mycobacterial agents in Mycobacterium tuberculosis and M. tuberculosis-infected macrophages in vitro as a model for early stage tuberculosis drug discovery