Pharmacometrics to characterize pharmacokinetics and optimize treatment in understudied populations by Gebreyesus, Manna Semere

“…In this thesis, I apply pharmacometrics for understudied populations with limited data across various therapeutic areas, including: optimizing dose of cefazolin, an antibiotic used forsurgical site infection prophylaxis, in children undergoing cardiac surgery with cardiopulmonary bypass; optimizing dose of rifabutin, an antibiotic used for TB, during lopinavir/ritonavir (LPV/r)-co treatment in children with TB-HIV co-infection; showcasing a model-based adherence monitoring tool using enalapril, an angiotensin-converting enzyme inhibitor for hypertension and heart failure, in a small cohort of African heart failure patients, and characterizing pharmacokinetics of esomeprazole, a proton pump inhibitor for hyperacidity and being investigated for preeclampsia, in patients with preterm preeclampsia. …”
Get full text

The optimization of gesture recognition techniques for resource-constrained devices

Get full text
Get full text

Optimal pricing for national park entrance fees in Zambia by Chikumbi, Lydia Mwelwa

Get full text

Optimal retirement savings : a South African perspective

Get full text

Telkom and the South African economy : achieving the optimal relationship by Baird, Peter Walther Orgell

Get full text

The design of an optimal, dynamic, multi-hop telemetry network by Nicholson, Gareth Andrew

Get full text

Optimization of Pile Construction Sequence Using CFA Machines by Ammar, Omar Wael

“…In most construction projects with deep foundations, piling activities are critical to the project schedule and often fall on the critical path. …”
Get full text
Get full text

Optimization Models for Seaport Operations and Empty Container Management

Get full text

Optimal Sizing of Solar Energy Systems at SolarAfrica by Roberts, Kyle Owen

Get full text

Particle swarm optimization : empirical and theoretical stability analysis

Get full text

Analysis, synthesis and optimization of complex cooling water systems

Get full text

Integration and optimization of hydrokinetic turbines in canals in South Africa

Get full text

Factors which affect optimal adherence to antiretroviral medications by Usman, Samuel

Get full text

An optimal commercially available wireless sensor network in viticulture

Get full text

Optimization and evaluation of heterologous lysozyme production in saccharomyces cerevisiae by Wilcox, Dale Adrian

Get full text

Optimal Extraction of Photovoltaic Cell Parameters for the Maximization of Photovoltaic Power Output Using a Hybrid Particle Swarm Grey Wolf Optimization Algorithm by Reindorf, Nartey Borkor, Abubakar, Ali

Get full text

Retrospective analysis of the utilisation of DNA analyses in the identification of human remains at Salt River Mortuary (Cape Town, South Africa) by Kambowo, Sophy Celine

Get full text

A retrospective audit of post-caesarean sepsis at Tygerberg Hospital by Coetzer, Marsel

Get full text

Particle swarm optimization and differential evolution for multi-objective multiple machine scheduling

Get full text
Get full text