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Investigating the nuclear import protein KPn߀1 as a cancer therapeutic target
Published 2022“…The aim of this study was to investigate a novel small molecule, Compound 60 (9-[(1-methyl-3-piperidinyl)methoxy]-4-[(6-methyl-2-pyridinyl)methyl]-7-(5-methyl-2-thienyl)-2,3,4,5-tetrahydro-1,4-benzoxazepine); by monitoring (i) its effect on cancer cell biology using cervical and oesophageal cancer cell lines, (ii) its effect on nuclear import activities associated with Kpnβ1, (iii) its in vitro ADME pharmacokinetics and in vivo anti-cancer properties and (iv) performing biophysical analysis of Kpnβ1:C60 interactions. …”
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Sleep quality and cognitive impairments in remitted patients with schizophrenia in Nigeria.
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A collective self-governance framework for urban facilities management settings: application at public transport interchanges in economically depressed areas in Cape Town
Published 2024“…These hypotheses were quantitatively tested using survey questionnaires and convenience sampling methods. …”
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The anti-cancer activity of extracts derived from millets and Kraalbos
Published 2022“…Results from these extracts show that only the methanol fractions of the Babala and Enforcer millets exhibited short-term cytotoxic activity against the MCF-7 and the MDAMB- 231 breast cancer cell lines. Five Kraalbos extracts (KB1, KB2, KB3, KB4 and KB5) were tested for their short-term cytotoxicity against the MCF-7 and MDA-MB-231 breast cancer cell lines. …”
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Vector boson production with the ALICE detector
Published 2018“…The production of W bosons is studied in p-Pb, p-p and Pb-Pb collisions at 5.023, 8 and 5.023 TeV centre-of-mass energies, respectively. …”
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Balance in recreational/non-professional dancers with snapping hip : a cross-sectional study
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Cell biological responses of prostatic tumour cell lines to irradiation and anticancer drugs
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Socio–Economic Factors and Health Status as Determinants of Public Service Retirees’ Life–Satisfaction in the South–West, Nigeria
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Exploring the peroxidase activity of ferriprotoporphyrin IX: towards understanding its cytotoxicity in the malaria parasite
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Structure activity relationship studies of ochratoxin A analogues
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Studies in the psychopathology, neurobiology and psychopharmacology of schizophrenia
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The separation of phenolic compounds from neutral oils and nitrogen bases
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Immune cell dysfunction and eicosanoid imbalance in chronic diabetic wounds
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The Development of an Economic Feasibility Decision Support System for a Building Automation and Control System
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The construction and validation of a health-related quality of life measure for women with endometriosis
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An Auditory profile of sclerosteosis
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Disease dynamics in patients with drug-resistant tuberculosis residing in a high incidence community
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