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GEOPHYSICAL AND HYDROCHEMICAL INVESTIGATIONS OF ABEOKUTA AND IKORODU AREAS OF SOUTHWESTERN NIGERIA
Published 2012-06Call Number: Loading…
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SPATIO-TEMPORAL PATTERNS AND ENVIRONMENTAL IMPACT OF INDUSTRIAL AGGLOMERATION IN THE LAGOS REGION, NIGERIA
Published 2014Call Number: Loading…
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EFFECTS OF POSTHARVEST HANDLING METHODS AND STORAGE CONDITIONS ON STORABILITY OF PEPPER (Capsicum frutescens L.) FRUITS IN SOUTHWEST NIGERIA
Published 2014-08Call Number: Loading…
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THE DISCOURSE OF GENERATIONAL DIFFERENCE IN SELECTED NOVELS OF MAYA ANGELOU AND TERRY MCMILLAN
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CULTURAL PERCEPTION OF MALARIA AND CHOICE OF THERAPY AMONG THE IBIBIO OF AKWA IBOM STATE, NIGERIA
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AFFINITY AND REACTIVITY STUDIES OF THE REACTION OF HUMAN (Homo sapiens) AND CAT (Felis catus) HAEMOGLOBINS WITH 5,5´-DITHIOBIS(2-NITROBENZOATE)
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- Engineering & Technology 2 results 2
- "The tense phrase (TP) domain is the domain that expresses grammatical tense, aspect and mood. Existing studies concentrated on describing the morph-syntactic features of the Igbo TP categories with little attention paid to their interaction and hierarchical order. This study, therefore, investigates the morpho-syntactic features and interaction of the functors with a view to determining their hierarchical order in the clause structure. Primary and secondary data were collected and subjected to syntactic analysis. Three main functors, Tense, Aspect and Negation, overtly occur in the Igbo TP area as verbal affixes and they exhibit two opposing patterns of morpheme order: V-T-ASP-NEG and T-ASP-NEG-V. The former, where the functors follow the verb, requires obligatory movement of the VP to spec TP, while the latter requires no such movement since the functors precede the verb. The study demonstrated that these morpheme orders are derived syntactically via operation merge with surface order corresponding to the hierarchical order. This is in contrast to preceding studies which assume mirror image where the linear order is the inverse of the hierarchical order. 1 results 1
- A nationwide equine influenza virus surveillance was carried out between January 1989 and January 1995 during which nasopharyngeal swabs, tracheal washes and respiratory tract tissue homogenates were obtained from symptomatic and asymptomatic equine species in various parts of Nigeria for virus isolation and characterisation. Three equine influenza viruses were independently isolated in 10-11 day old embryonated hen eggs and Madin Darby canine kidney monolayer cells with TPCK-trypsin incorporated into the culture medium. The virus isolates were characterized antigenically, immunogenically and genetically which made them the first equine influenza viruses isolated and characterized in tropical Africa. Antigenic analyses with mono-specific antisera raised against a number of respiratory disease viruses including Paramyxoviruses, Adenoviruses, Herpes viruses, Alphavirus, Rhinoviruses, Equine arteritis viruses, African horse sickness viruses and Influenza viruses showed that the three virus isolates were influenza A viruses while haemagglutination and neuraminidase inhibition assays using influenza virus specific Mabs and polyclonal antisera showed the three viruses to be antigenically H3N8, members of equine-2 subtype of influenza A viruses. The three isolates were respectively named A/Equine/Ibadan/4/91, A/Equine/Ibadan/6/91 and A/Equine/Ibadan/9/91 in accordance with the recommendations of the World Health Organisation and the International Committee on Virus Taxonomy. Their antigenic cross-reactivity with panels of Mabs and polyclonal antisera indicated that the three viruses were antigenically divergent although they were all H3N8 viruses and were representatives of a homogenous population. They were reactive with Mabs and antisera directed against H3 equine viruses isolated in 1963, 1976, 1979, 1981 and 1986. This broad reactivity suggested that these isolates were similar to but not still different from those isolated in Europe and USA between 1963 and 1987. Virus protein synthesis and cleavability of the HA polypeptide in tissue culture were investigated by pulse-chase experiments. The results showed some heterogeneity in the non-glycosylated polypeptides particularly those of the ribonucleoprotein (RNP) complex while the HA glycoproteins of the three viruses were not cleaved in any of the cell types used in contrast to equine H7 and pathogenic avian H5 and H7 HAs. The molecular weights of the polypeptides were within the range previously determined for influenza A viruses. The heterogeneity of the RNP complex and antigenic divergence of the viruses’ HAs were confirmed by sequence analysis carried out in molecular studies. Virus infectivity was investigated by plaque assay using chicken embryo fibroblast (CEF) monolayer cells and virus titration in embryonated hen eggs. The results showed that the viruses were infectious with plaguing efficiency being comparable to efficiency of virus infectivity in embryonated hen eggs. Infectivity, antigenicity and immunogenicity of the three viruses were confirmed in-vitro using peripheral blood lymphocytes in lymphoproliferation assays and in-vivo in an equine model in which the viruses induced haemagglutination inhibiting and protective neutralising antibodies following experimental infections. The proliferating cells were also characterised and the immunoglobulin isotypes produced were determined. Molecular characterisation and genetic analyses of the three viruses were accomplished to determine the origin of the genes encoding the virus non-glycosylated polypeptides as well as those of the surface HA glycoprotein. Reverse transcription (RT) results showed the eight RNA segments of the three isolates and confirmed them as influenza A virus RNAs. No subgenomic RNAs or defective interfering particles were observed in the RNA transcripts. Nucleotide sequence analyses were carried out using three sequencing strategies of cDNA, vRNA and plasmid DNA sequencing with the dideoxy chain termination procedure. Partial nucleotide sequences were obtained from cDNAs, vRNAs and plasmid DNA clones of RNA segments 1, 2, 3, 5, 7 and 8 with the method of multiplex RT/PCR and cycle sequencing using radiolabelled segment specific oigonucleotides of 18, 24 or 25 mers. Complete nucleotide sequences of segment 4 (HA genes) were also determined on the same PCR products (cDNA) and vRNA using end-labelled oligonucleotides of both plus and minus sense. The partial nucleotide sequence data were analysed using a programme for "best-local-homology- rapid-search" on a digital array processor while the complete HA nucleotide and deduced amino acid sequence analyses were carried out using the University of Wisconsin Genetics Computer Group (GCG) package of programmes. Phytogenetic analysis was done with the distances, neighbour joining and DNAPARS of the PHYLIP package. Analyses of the viruses’ gene sequences confirmed that their genomes were similar to each other and to those of other H3N8 influenza viruses isolated from equines and also revealed the origin, evolution and genetic relatedness of the genes. Comparison of the partial cDNA sequences with virus DNA sequences in the database (EMBL sequence library) showed that for segments 1, 2, 5, and 7, the closest related sequences were from equine H3 viruses isolated in 1986 in USA (Tennesse/5/86 for segments 2, 5 and 7, Kentucky/2/86 for segments 1 and 5. Segment 5 was equally related to both viruses). The nucleotide sequence for segment 3 was most closely related to an equine-1 virus isolated in U.K. in 1973 (London/1416/73, H7N7) probably due to genetic exchange while segment 8 sequence was most closely related to an equine H3N8 virus isolated in U.K. in 1976 (Newmarket/76). The complete nucleotide and deduced amino acid sequences as well as phytogenetic analysis of the HA genes (RNA segment 4) showed a closer relationship albeit with nucleotide and amino acid substitutions between the three Ibadan viruses and those that were isolated in Europe in 1989 and 1991, the prototypic European strain, Suffolk/89 and Arundel/12369/91 isolated in U.K., Taby/91 isolated in Sweden, Hong Kong/92 isolated in the Far East in 1992 and Laplata/1/93 isolated in South America. These findings group the Ibadan viruses with those predominating and contemporarily causing disease in the Western Hemisphere rather than with viruses previously isolated from the north and south of African continent. Variation was observed in the nucleotide sequences of the Ibadan viruses HA genes. Some of the base changes resulted in amino acid changes which mapped to antigenic sites or within signal sequence in the HA1 domain as a result of a process of antigenic or genetic drift. The Ibadan viruses also showed some variation from the prototypic European virus (Suffolk/89) and these base changes also resulted in amino acid changes resulting in antigenic drift. Phytogenetic analysis showed the evolutionary lineages in equine H3 viruses isolated since 1963 along two paths one of which included the Ibadan viruses as well as viruses isolated in Europe between 1989 and 1991 and the Far East in 1992 and S. America in 1993 which form the 1989/93 cluster while the other lineage included viruses isolated in South America in 1987 and 1988 (Brazil/87, Laplata/88) and in the Far East in 1971 (Tokyo/3/71) all of which are very close to the original prototype equine-2 virus (Miami/63). These results demonstrate a faster evolutionary rate for recent equine H3 HA genes away from the original prototype virus. Overall, the results of these studies have (i) confirmed the occurrence of equine-2 H3N8 influenza viruses of distinct lineages in Nigerian equine populations in a tropical environment (ii) indicated antigenic drift among equine H3N8 viruses as earlier reported and confirmed that drift strains can co-circulate in equine populations, (iii) showed the origin, evolution and genetic relatedness of the viruses genes as well as their biological characteristics, (iv) provided the hitherto unavailable information on the status of equine influenza virus in this part of the world and (v) served to re-emphasise the potential of influenza virus for rapid global spread and the need for better control strategies. 1 results 1
- ANN 1 results 1
- ARIMA 1 results 1
- Adjectifs franqais 1 results 1
- Adjectifs yoruba 1 results 1
- African American literature 1 results 1
- African American literature has been predominantly a male-preserve in the task of narrating the experience of slavery and its relics of denigration before the advent of reactionary literature by black female writers. Studies on female-authored African American literary works have concentrated on responding to male-authored representations of the tensions of racism, internal crisis of man-woman relationships and the challenges of empowering the black female character. Little attention has been paid to African American female writings across generations and gender categories. This study, therefore, investigates the narrative thrusts of selected works of Maya Angelou and Terry McMillan to determine the dimensions of divergence across generations of African American female writers. The study adopts Alice Walker‘s womanist theory and bell hooks‘ feminist theory which account for differences in the construction of black women consciousness. Six novels – Maya Angelou‘s I Know Why the Caged Bird Sings (1970), Gather Together in my Name (1974), and The Heart of a Woman (1981), and Terry McMillan‘s Waiting to Exhale (1992), A Day Late and a Dollar Short (2001) and The Interruption of Everything (2005) – were purposively selected. The texts are subjected to literary and comparative analyses. From the first autobiography I Know Why the Caged Bird Sings to the last The Heart of a Woman, Angelou offers detailed testimony on the effects of displacement on the individual psyche and the black community. Maya Angelou‘s selected novels reveal the creation of a collective communal memory through the use of the autobiographical prose form. Angelou‘s narratives reveal her understanding of history, her reverence for memory of collective black folk tradition and represent the Black Arts era. In contrast, Terry McMillan‘s Waiting to Exhale, A Day Late and a Dollar Short and The Interruption of Everything reveal a paradigm shift from the communal experience to the individual, the internal crisis among individuals in the family and aspiration of specific sentiments as she projects the female character as ambitious and daring. McMillan‘s fiction stands out in several ways. She revises and borrows recognisable literary conventions to project the changing roles of women to reinforce her radical perspective. However, the choice of professionally successful black women as characters in her novels relates to the drastic increase in the population of working class women in the 1990s and reflexive of the post-womanist tradition. Her works accentuate the quest for personal liberty, romance and intimate relationships as the central conflicts facing black female protagonists. Although two decades separate Angelou‘s I Know Why the Caged Bird Sings and Terry McMillan‘s Waiting to Exhale, a close reading of the novels reveals that the texts derive qualitative interpretations from the unique difference in ideas and aesthetics represented by Alice Walker, bell hooks and other Black feminists. While Maya Angelou‘s novels keep within the womanist tradition, those by Terry McMillan are radically feminist and modernist in orientation. Thus, the two writers exemplify the Black Arts era and post-womanist literary generation respectively and differently situate the novels within specific historical, socio-political, economic, gendered and literary contexts. Key words: Generational difference, Womanism, African American literature, Maya Angelou, Terry McMillan. Word count: 498 1 results 1
- Al-Majaz 1 results 1
- Alarinjo 1 results 1
- Aquifers 1 results 1
- Arabic sufi literature 1 results 1
- Arts & Humanities 1 results 1
- Aspect 1 results 1
- Background/Aim: Radiology residency was initiated nearly 30 years ago in the west African subregion, but accompanying formal subspecialty training has been developed within the 30 year time span. In contrast, subspecialization has evolved over the past 25 years in developed countries. The aim of this study was to determine residents' perspective about radiology subspecialization training in west africa. Materials and Methods: Semi- structured, self- administered electronic questionnaire were sent to residents at different levels of training via-email and during update courses. Data analysis was performed using SPSS version 15.0(BM) package. Quantitative variables were expressed using summary statistics including means and medians. Descriptive analysis was performed for the qualitative variables using frequencies, proportions and charts. Statistical significancwe was set at the 5% level using two tailed P values. Results: There were 117 respondents 85(72.6%) males and 32(27.4%) females. A total of 110 (94%) were aware of the various subspecialties in radiology with neuroradiology being identified by all as seperate subspecialty. Interventional radiology topped the choice of subspecialty with 61(52.1%) respondents, and 67(57.3%) would prefer that subspecialties be introduced in phases. Ultrasound, basic x-ray, momography equipment, and computed tomography scanners are availabe in many of the training centers. 116(99.1%) of the resident believed that there is a need for subspecialization in the subregion. Conclusion: Our study demonstrates the need for subspecialzation in west Africa. To achieve this goal, collaboration and support from well-established radiology residency and fellowship training programs based in developed countries is necessary. 1 results 1
- Background: Behaviour change which is highly influenced by risk perception is a major challenge that HIV prevention efforts need to confront. In this study, we examined the validity of self-reported likelihood of HIV infection among rural and urban reproductive age group Nigerians. Methods: This is a cross-sectional study of a nationally representative sample of Nigerians. We investigated the concordance between self-reported likelihood of HIV and actual results of HIV test. Multivariate logistic regression analysis was used to assess whether selected respondents’ characteristics affect the validity of self-reports. Results: The HIV prevalence in the urban population was 3.8% (3.1% among males and 4.6% among females) and 3.5% in the rural areas (3.4% among males and 3.7% among females). Almost all the respondents who claimed they have high chances of being infected with HIV actually tested negative (91.6% in urban and 97.9% in rural areas). In contrast, only 8.5% in urban areas and 2.1% in rural areas, of those who claimed high chances of been HIV infected were actually HIV positive. About 2.9% and 4.3% from urban and rural areas respectively tested positive although they claimed very low chances of HIV infection. Age, gender, education and residence are factors associated with validity of respondents’ self-perceived risk of HIV infection. Conclusion: Self-perceived HIV risk is poorly sensitive and moderately specific in the prediction of HIV status. There are differences in the validity of self-perceived risk of HIV across rural and urban populations. 1 results 1
- Background: Magnetic resonance imaging (MRI), an advancement which followed computed tomography (CT) is expensive and inaccessible in most dveloping countries. However it is the procedure of choice in evaluating sellar and parasellar lessions. Its major advantages are its superior soft tissue contrast differentiation, its capacity for multiplanar imaging and nonexistence of ionising radiation. Its use is relatively new in Nigeria, a developing economy in Africa. Since its introduction in 2005, it has been utilised extensively for neuroimaging at the University College Hospital (UCH), Ibadan; a large hospital is south-western Nigeria. Objective: To review the role and pattern of low field MR imaging in sellar and parasellar lesions presenting to a tertiary care centre in Nigeria. Methods: All 62 patients with clinically suspected sellar and parasellar masses, referred to the department of Radiology, UCH Ibadan for MRI between December 2006 and January 2010 were retrospectively analysed. The examinations were performed using an open 0.2T permanent magnet MR unit. T1W, T2W,T2/ FLAIR, TOF and T1W post gadolinium DTPA sequences of the sellar region were obtained. Result: Of the 62 patients, there were 27 males and 35 females. The modal age group was 40-49 years with a mean age of 39.94 years (±16.65years). Twenty-four cases (38.7%) had histological daignosis, of which 20(83.3%) were consitent with initial MRI diagnosis. Pituitary adenomas were the commonest (58.06%) lesions of the sellar and parasellar regions. Others include parasellar meningiomas, cranipharyngiomas, and gaint aneurysms. Headache and visual impariment were the major presenting features and showed no significant correlation with tumor size. Conclusion: The use of low filed MRI in the diagnostic evalauation of patients with suspected sellar or parasellar lesions in developing countries of low economic resource is commendable as it provides beneficial outcomes in management. 1 results 1
- Bednets 1 results 1
- Biology 1 results 1
- Capsicum frutescens 1 results 1
- Coarse-grained model 1 results 1
- Combining ability 1 results 1
- Commodity price shocks Social accounting matrix 1 results 1
- Communication & Media 1 results 1
- Comparative literature 1 results 1
- Computable General Equilibrium Model 1 results 1
- Computer Science & IT 1 results 1
- Correlation 1 results 1
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