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Addressing challenges in the treatment of tuberculosis and tuberculosis meningitis: a pharmacometric approach
Published 2025“…Secondly, TB management in hospitalised patients becomes more difficult since they often face more advanced stages of the infection, as well as physiological changes that could impact the pharmacokinetics of anti-TB drugs. …”
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Polysaccharide/Drug Nanocomposite Fabrication And Their Interaction With Cancer Cell Lines In-Vitro
Published 2026“…A Quality by Design (QbD) approach was applied to optimize the nanoparticle formulation using Plackett–Burman and Box–Behnken designs. …”
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A review of the green economy in Cape Town: local policy in the light of international approaches
Published 2017“…The green economy is an approach to economic activity that has been developed in an effort to mitigate against this and attempt to shift the world economy onto a more sustainable course. South Africa has a particularly carbon-intense economy, and as such bears a considerable burden to follow this shift. …”
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Narrative discourse characteristics of South African Afrikaans speaking Cape Coloureds with aphasia
Published 2017“…The narrative discourse productions were transcribed and analysed using more stringent reliability measures. Measures of reliability were obtained by calculating inter-rater and intra-rater reliability measures. …”
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Not all models are created equal: assessing parameterisations of iron dynamics in ocean biogeochemical models
Published 2020“…The free scavenging model (FePISCES) resulted in dissolved iron concentrations being two to three times greater than with the standard formulation (FeBFM), which used a simpler formalism for scavenging. …”
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Rates of Switching First-Line Antiretroviral Regimen Tenofovir-Emtricitabine-Efavirenz combination in a Primary Care Service in South Africa
Published 2020“…Introduction: Tenofovir-Emtricitabine-Efavirenz (TEE) fixed-dose-combination (FDC) has been recommended since 2013 as the first-line antiretroviral therapy (ART) for treating HIV for people living with the virus (PLWH) in South Africa. More evidence has emerged to show long term adverse effects of Efavirenz(EFV). …”
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A contact-implicit direct trajectory optimization scheme for the study of legged maneuverability
Published 2023“…The second section of this dissertation describes innovations in the formulation of these trajectory optimization problems as nonlinear programming problems (NLPs). …”
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Extent of misuse and dependence of codeine-containing products among medical and pharmacy students in a Nigerian University
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Extent of misuse and dependence of codeine-containing products among medical and pharmacy students in a Nigerian University
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The perceptions of diverted female youth sex offenders regarding the factors that contributed to their offending
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Implications of complexity leadership on organisational adaptability in dramatic social change contexts
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Pasting properties of teff, maize, and potato starches with added microcrystalline cellulose and cellulose nanofiber
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A beam finite element for the analysis of structures in fire
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A competitive strategy framework for E-business start-ups
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Hybrid non-linear model predictive control of a run-of-mine ore grinding mill circuit
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Nonlinear heat transfer and thermo mechanical stress analysis using finite elements.
Published 2014“…The formulations are implemented in an existing temperature independent nonlinear finite element stress analysis code. …”
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