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The impact of neutralizing antibody and ADCC responses on HIV-1 envelope evolution in early infection
Published 2018“…In contrast, while the two V2 nnAbs we tested were narrow and weak, the two nnAbs targeting CD4-induced epitopes (A32 and C11) mediated the broadest (78-100%) and most potent (0.06-0.81 μg/mL) ADCC against this panel. …”
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The efficacy of coumarin derivatives against persistent mycobacterial biofilms
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Biological activity of Sinularia notanda
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Implementing a prototype HPy backend for Cython: improving Python extension performance
Published 2026“…Our HPy backend replaces C API functions, variables, and macros generated by Cython with macros that map to either the C API or HPy. …”
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A dipole with active metasurface reflector for polarization reconfigurability
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Design and development of an adaptive external bone fracture fixation system
Published 2020“…The system is to be able to stabilise and offer correction of planar bony deformities via controlled shape change. The functional verification of the device was limited to (according to the scope) stress testing. …”
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Hybrid hydrogels based on RAFT mediated poly(N-vinyl pyrrolidone)
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The development of an English Health-Related Quality of Life (HRQoL) measure for very young children, to be completed by proxy
Published 2018“…These items were further reduced through subsequent testing of items and retesting of a preliminary measure. …”
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Modeling a systems-based framework for effective IT auditing and assurance for less regulatory environments
Published 2019“…Auditors, as a result, are looked upon to expand their role to leverage the functions of those charged with governance and management. …”
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A reusable signal processing architecture for satellite based communication systems
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The development of a radiolabelled macromolecule as a therapeutic agent for the treatment of cancer
Published 2015“…In summary, this thesis outlines a number of synthetic, radiological and biological aspects towards the development of a fully functioning radiolabelled macromolecular bioconjugate that could be tested for improved targeted cancer radiotherapy.…”
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Whole-genome transposon mutagenesis to elucidate the genetic requirements for vitamin B12 biosynthesis and assimilation in mycobacteria
Published 2022“…In addition, the results add further evidence in support of the functionality of the cobalamin riboswitch upstream of metE. …”
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Oxidative dehydrogenation of ethane with carbon dioxide over iron-nickel nano-alloys supported on metal oxide overlayers
Published 2023“…Promoters such as Fe-based oxides have been studied to enhance the CO2-activation functionality and stability of the oxides [5]. A Density Functional Theory (DFT) study suggested that bimetallic alloys can have superior activity for CO2-activation compared to their monometallic counterparts [16]. …”
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Pathways of intracellular protein degradation in cultured muscle cells
Published 2018“…In the case of 'short-lived' proteins (pre-labelled for 1 hour), the initial degradation rate was 6,5% per hour, which rapidly declined, reaching the basal rate of 1,5 % after 4 h. …”
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Survey of medical, dental and nursing services in centres for intellectually and physically disabled children in Cape Town and its environs
Published 2017“…Fifteen centres receive visits from Community Nurses and these are local authority nurses in the main. Their functions are limited in all but one case to contraception, immunisation, Heaf testing or genetic services. …”
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Automating land cover classification using time series NDVI : a case study in the Berg River Catchment Area
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Influence of Processed Natural Black Sand vs. Natural White Sand and Silica Flour as Additives to Oil-Well Cementing Applications
Published 2023“…Phase #1 (Pilot Phase) compared natural black sand and white sand additives to Portland cement without any other additives in ambient conditions and water to cement ratio (W/C) of 0.5. Phase #2 of the experiments studied the impact of natural black sand and white sand on Portland cement, with the addition of anti-foam and dispersant, under a testing temperature of 100 F, a pressure of 4400 psi, and W/C ratio of 0.46. …”
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