Proteomics of physiologically relevant stresses on model mycobacterium tuberculosis organisms, and the effects on virulence by Ganief, Muhammad

“…We also performed LC-MS/MS based proteomics to probe the temporal host response to Mycobacterial infection, using murine macrophage cell models of both circulating and alveolar macrophages. …”
Get full text

Developing a ball mill model that incorporates grate and overflow discharge configurations by Mwale, Adolph Ntaja

“…The model was later sub-developed into two models each specific to the discharge configuration type, the grate and overflow. …”
Get full text

Continuum Damage Mechanics to Model Glulam Beams Reinforced with Glued-In Steel Cables by Rhodes, Aaron

“…This study aims to investigate the use of Continuum Damage Mechanics (CDM) for the computational modelling of timber, a material known for its high variability and anisotropy. …”
Get full text

Modelling the long-and-short run dynamics of share price movements in the resource sector by Davids, Megan

“…Models were constructed for IMPLATS, HARMONY, GOLDFIELDS, SASOL and SAPP!. …”
Get full text

A study of the thermal degradation of model compounds of amine-cured epoxide resins by Percy, Vivienne Ann

“…The effect of the presence of alumina, which b.as been used as a filler for epoxide resins, on the thermal stability uf the model compounds has been examined. The possibility that the degradation of model compounds may be used as a synthetic route to benzofuran has been investigated.…”
Get full text

Molecular modeling studies of carbohydrate vaccine antigens: informing the future of vaccine design by Richardson, Nicole

“…As computational power continues to grow, the cost and time associated with modeling may decrease, further enhancing the accessibility of this methodology for future vaccine development endeavors.…”
Get full text

Application of the Lagrangian descriptors method to Hamiltonian systems with emphasis to models of barred galaxies by Theron, Dylan Grant

“…We first study a Hamiltonian system of galactic type to highlight normally hyperbolic invariant manifolds (NHIMs), examining the impact of different pattern speeds and energy levels on the NHIMs' structure and determine how these features influence orbital morphologies seen in the model's configuration space. Thereafter, we apply the LDs method to a dynamical system whose evolution is governed by fractional ordinary differential equations (FDEs) and showcase the utility of this method in qualitatively revealing phase space structures for systems described by FDEs. …”
Get full text

Towards Integrated Business and Partnership Models for Universal Energy Access in Kenya and Rwanda by Pailman, Whitney Lisa

“…Integrated electrification models have garnered significant attention in the energy access discourse as an essential element of achieving universal access to electricity. …”
Get full text

Population pharmacokinetic modelling to optimise treatment for children with Rifampicin-resistant TB and HIV by Van der Laan, Louvina Elizabeth

“…Population pharmacokinetic modelling, the state-of-the art technique to interpret pharmacological data, can play a pivotal role for therapeutic optimization in children, since it enables characterisation and inclusion of the effects of important developmental factors, thus allowing for determination and evaluation of effective yet safe RR/MDR treatment in children.…”
Get full text

Domestic wheat demand in a deregulated environment: modeling the importance of quality characteristics by Edwards, Lawrence James

“…Thus, a demand orientated cost minimising non-linear programming model (Input Characteristic Model) is developed which evaluates the demand for different wheat sources as a function of their quality characteristic levels, characteristic variances and prices. …”
Get full text

A population dynamics model for analysing the effect of rainfall seasonality on vegetation in the Karoo by Govender, Serayen

“…The population growth is modelled using state-space models, incorporating both an ecological process model and an observation model. …”
Get full text

Quantifying polyphosphate energy for modelling of polyphosphate accumulating organisms behaviour in anaerobic digestors by Chen-Chen, Cornelius

“…The findings support more accurate modeling approaches and highlight the importance of considering energy transfer mechanisms in linked AS-AD systems.…”
Get full text

Latent class modelling of respiratory outcomes in a South African birth cohort by Mccready, Carlyle

Subjects: “…latent class mixed effect models (LCMM)…”
Get full text

A comparative analysis of machine learning models for forecasting JSE Stock Returns by Muir, Cameron James

“…This study examines the application of machine learning models to predict the cross-section of Johannesburg Stock Exchange (JSE)- listed share returns. …”
Get full text

Mixed-ligand diruthenium complexes: theoretical modelling and interpretation of electronic absorption spectra by Mutomb, Jean-Luc

“…This study therefore investigates the characteristics of Ru₂(μ-O₂CCH₃)₃(μ-2-Fap)X complexes using time-dependent density functional theory (TD-DFT) calculations that utilize the PBE/LANL2DZ level of theory and an Integral Equation Formalism Polarizable Continuum (IEF-PCM) solvent model using water, DCM and DMSO. Calculation of natural transition orbitals (NTOs) and spectrum deconvolution methods have aided in characterizing the electronic transitions of the prominent UV band at 250-350 nm as a combination of δ(Ru₂) → π*(Np,C), π(Cl) → π*(Cp,Np) and π(Cl) → π*(Cₐ) transitions, where the subscript “a” and “p” represents the aniline and pyridine moieties, respectively. …”
Get full text

Assessing GridSim for modeling the global distribution of next-generation astronomy data by Tunbridge, James K

“…The implementation of the proposed design for an ECOFEN model extension in GridSim is a project for future work after one unsuccessful attempt to implement the model in GridSim. …”
Get full text

Implementing a filtered term structure model in the South African bond market by Ririe, Angela

Get full text

Modelling the impact of future climate change on subregional wheat production in the Western Cape by Wallace, Michael

Get full text

The application of the surface energy balance system model to estimate evapotranspiration in South Africa by Gibson, Lesley Anne

Get full text

Sea surface temperature anomalies in the South Indian ocean : observations and atmospheric modelling by Hansingo, Kabumbwe

Get full text