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On Synthesis, design and resource optimization in multipurpose batch plants
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Generative design using Lindenmayer-systems and numerical optimization
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Multi-objective optimization techniques in electricity generation planning
Published 2014“…The objective of this research is to develop a framework of multi-objective optimization (MOO) models that are better capable of providing decision support on future long-term electricity generation planning (EGP), in the context of insufficient electricity capacity and to apply it to the electricity system for a developing country. …”
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Design optimization of gas-to-liquid biosludge management systems
Published 2015“…Results indicate that the decay constant specific to the investigated GTL biosludge is 0.0145day-1. The design model consists of three sub-models: a sizing and design sub-model, a simulation sub-model, and a cost and optimization sub-model. …”
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Multi-skilled Labor Optimization with Partial Allocation of Resources
Published 2021“…Through a multi-step methodology, a model that optimizes the allocation of multi-skilled labor resources was developed. …”
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Energy and cost optimal scheduling of belt conveyor systems
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Trajectory optimization inspired pneumatic locomotion on compliant terrains
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Analysis, synthesis and optimization of complex cooling water systems
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Pharmacometrics to characterize pharmacokinetics and optimize treatment in understudied populations
Published 2025“…In this thesis, I apply pharmacometrics for understudied populations with limited data across various therapeutic areas, including: optimizing dose of cefazolin, an antibiotic used forsurgical site infection prophylaxis, in children undergoing cardiac surgery with cardiopulmonary bypass; optimizing dose of rifabutin, an antibiotic used for TB, during lopinavir/ritonavir (LPV/r)-co treatment in children with TB-HIV co-infection; showcasing a model-based adherence monitoring tool using enalapril, an angiotensin-converting enzyme inhibitor for hypertension and heart failure, in a small cohort of African heart failure patients, and characterizing pharmacokinetics of esomeprazole, a proton pump inhibitor for hyperacidity and being investigated for preeclampsia, in patients with preterm preeclampsia. …”
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Optimal composition of hedge fund replicators in South Africa
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Optimal scheduling of an integrated batch and continuous process system
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Optimal management of household load under demand response
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Stall and spin recovery using optimal trajectory planning
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Optimizing flotation performance using extremum seeking control
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Optimizing investments' cash flow: a scheduling approach.
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The design of an optimal, dynamic, multi-hop telemetry network
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Optimal energy management of crushing processes in the mining industry
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Optimizing learning & teaching on paediatric ward rounds
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Optimal Sizing of Solar Energy Systems at SolarAfrica
Published 2019Get full text
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