A geochemical assessment of old slimes tailings from two South African kimberlite diamond mines : implications for mineral-carbonation resource estimation

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The influence of self-efficacy and perceived organisational support on idea implementation by Grobler, Rikus

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TECHNOLOGY AS A TRANSFORMATIVE TEACHING AND LEARNING TOOL IN MIDWIFERY EDUCATION : PERSPECTIVES OF NURSE EDUCATORS

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The economic burden, patients' well-being, and social determinants related to diabetes in South Africa by Hellebo, Assegid

“…Methods: The thesis combined diverse methodological approaches to investigate the impact of T2D in South Africa. …”
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Modelling breakthrough curves and investigating the impact of models and numerical properties on parameter estimation by Silavwe, Davy Danny

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In vitro metabolism studies to inform physiologically-based pharmacokinetic modelling of mefloquine, ritonavir and proguanil by Cloete, Cleavon K

“…The ability of ritonavir to induce CYP1A2 activity was also explored using the available model by optimizing its CYP1A2 induction capabilities through parameter optimization. …”
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Using turbine expanders to recover exothermic reaction heat for the combined production of power and chemicals

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Geometric and numerical optimisation of single- and two-phase convective heat transfer in microchannel heat sinks by Ariyo, David Olugbenga

“…Stability of optimal results was ensured in the simulations and optimisations, and in the critical heat flux computations.…”
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Development of a ray tracer for concentrating solar power systems by Bode, Sebastian-James

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Circuit model design of conical transmission line power combiners and isolation of reactive combiners by Beyers, Ryno Dawid

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Protection-based Distributed Generation Penetration Limits on MV feeders - Using Machine Learning by Nxumalo, Emmanuel

“…This brings about a limitation to this method, planning inadequacies, and longer connection approval periods. …”
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Production function analysis of the sensitivity of maize production to climate change in South Africa

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The effect of awareness at the medium access control layer of vehicular ad-hoc networks by Booysen, Marthinus J.

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Preformulation solid-state supramolecular beneficiation of selected active pharmaceutical ingredients and a novel drug candidate by Noonan, Terence James

“…The compounds selected were: Clevudine, an established drug that is currently in use for the treatment of chronic hepatitis B infections, 6-(3- (Methylsulfonyl)phenyl)-3-(4-(methylsulfonyl)phenyl)-imidazo[1,2-b]pyridazine (MMV652103), a novel antimalarial drug candidate that displayed good in vitro potency against multidrug resistant and sensitive plasmodial strains and ()-α-lipoamide, a bioactive antioxidant that is currently in use for the clinical treatment of diabetic neuropathy and has other potential uses e.g. as an antiretroviral agent. The methods utilised in pursuit of novel solid-state forms of the compounds included a combination of crystal engineering and experimental screening for polymorphs, solvates/hydrates, cyclodextrin (CD) inclusion complexes, pharmaceutical salts and co-crystals. …”
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Model based fault detection and isolation approach for actuator and sensor faults in a UAV by Madutlela, Potego

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Infrastructure implications of a green economy transition in the Western Cape Province of South Africa : a system dynamics modelling approach by York, T. A.

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Thermodynamic design optimisation of an open recuperative twin-shaft solar thermal Brayton cycle with combined or exclusive reheating and intercooling by Meas, Matthew Robert

“…In this work, optimal design of three common open solar thermal Brayton cycle variants is investigated and compared using principles of the second law of thermodynamics and the method of entropy generation minimisation. …”
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Trajectory Optimisation Inspired Design for Legged Robotics by Fisher, Callen

“…The results of the study revealed that the optimal method to accelerate was to launch straight into the desired gait (for both bipeds and quadrupeds), with a sliding mass template model emerging for all results. …”
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Development of an indoor positioning system to create a digital shadow of production plant layouts by Hermann, Julian

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Exploring the impact of novelty and objective-directed evolution in company with MAP-Elites and HyperNEAT by Breytenbach, Jeremy

“…MAP-Elites is referred to as an illumination algorithm because by retaining these elite agents in the population, we expect to increase the chances of exploring and thus illuminating novel, yet potentially high-performing regions of the search space. To evaluate these methods, we use Keep-away, a simulated collective robotics task within the RoboCup football framework as a case study. …”
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