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Differential effects of combinations of anti-retrovirals and progestins on gene expression and HIV-1 replication in cells of the female genital tract
Published 2018“…The present study aims to investigate the effects of the ARVs dapivirine (DPV), tenofovir disproxil fumarate (TDF) and a panel of progestins, alone and in combination with each other, on the expression of immune function genes relevant to HIV acquisition, on steroid receptor activity, and on HIV replication. …”
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Synergism between immune activators and progestogens: differential effects on gene expression and HIV-1 replication and the role of the glucocorticoid receptor
Published 2019“…In addition, there is evidence suggest that MPA and LNG impairs the integrity of mucosal barrier of the FGT. This study investigated the central hypothesis that MPA, NET and LNG acting alone or in synergy with immune activators [tumour necrosis factor-alpha (TNF) and lipopolysaccharide (LPS)] via the glucocorticoid receptor (GR) regulate the expression of genes of relevant for maintaining the integrity of genital tract mucosal surfaces, mucosal permeability, select immune function genes and HIV-1 replication. …”
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Evaluating Applicant Reactions to a Gamified Assessment of Personal Values: Developing and Testing a Theoretical Model
Published 2023“…The present study developed and tested a theory of applicant reactions to a gamified pre-employment assessment of personal values. …”
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The Role of Good Faith: A Case Study on the Application of Good Faith in the CISG
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Studies in risk perception and financial literacy: applications using subjective belief elicitation
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Study of ternary complexes of cucurbit[8]uril and their applications in self diagnostic composites
Published 2021“…Self-assembly in supramolecular systems has profound implications on creating the next generation of smart materials, with potential applications in self healing, energy storage, stimuli responsive hydrogels and sensors. …”
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A pharmacokinetic and efficacy study of Lumefantrine in mice: evaluating the application of Pheroid™ technology
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A study of the feasibility of advanced hybrid thermoplastic composites for aerospace and automotive applications
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An application of personal construct theory to a study of retail sales person effectiveness
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A language application for Health Science students : a study on user experience
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Guidelines for implementing a new manufacturing system and a case study application
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The application of the Alexander technique to the teaching and performing of singing : a case study approach
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The South African print media, 1994-2004 : an application and critique of comparative media systems theory
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