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Development Of Recombinant Immunotherapeutics for Triple-Negative Breast Cancer (TNBC)
Published 2024“…This study aimed at developing single chain fragments of variability (scFvs) derived from publicly available sequences of antibodies that target three CSRs overexpressed in TNBC, genetically fused to wild-type ETA (wt ETA) or a mutant version of ETA that was generated using advanced computer simulation by our collaborating partner, Professor Paolo Carloni from Forschungszentrum Jülich, Germany. …”
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Retrospective review: diagnostic performance of PI-RADS V2.1 4 and 5 lesions in predicting clinically significant prostate cancer at Groote Schuur Hospital, South Africa
Published 2025“…PI-RADS (v2.1) category 4 revealed a lower-than-expected correlation to international performance standards and is proposed to be the result of multiple interplaying factors such as reporting inexperience, inter-rater variability, suboptimal image acquisition and patient preparation and misrepresentative prostate biopsy. …”
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Vulnerability, resilience and climate adaptive strategies of forest-dependent communities in Central and Southern Malawi
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Characterisation of inducible proteins in the HepG2 cell line proteome
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Gold mineralization in the Amani area, southwestern Tanzania
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Relationship of pavement layers’ bearing capacity between laboratory DCP tests and field performance
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Non-destructive assessment of leaf composition as related to growth of the grapevine (Vitis vinifera L. cv. Shiraz)
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Fidelity and costs of implementing the integrated chronic disease management model in South Africa
Published 2021“…Conclusion: There was some variability of fidelity scores on the components of the ICDM model by PHC clinics, and there are multiple (context, participant responsiveness, intervention complexity and facilitation strategies) interrelated moderating factors influencing implementation fidelity of the ICDM model. …”
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Evaluation of a data-driven primary sedimentation tank model using settleometer data
Published 2023“…These five SVGs are characterized by different proportions of settleable BPO (BPOset), settleable UPO (UPOset) and settleable ISS (ISetS). Due to variability in wastewater (WW) characteristics from plant to plant, the DDPST model requires settleability data that is specific to a plant to make correct predictions. …”
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Practical probabilistic systems for satellite image segmentation and classifcation
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Immune cell dysfunction and eicosanoid imbalance in chronic diabetic wounds
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Towards using the light falling weight deflectometer as a construction control device
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Epidemiology of bluetongue virus with special reference to the Mnisi area, Mpumalanga Province, South Africa
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Development and validation of a South African English smartphone-based speech-in-noise hearing test
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Optimizing soil organic carbon stock assessments for spekboom reforestation of degraded lands in the Eastern Cape, South Africa
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Rangeland degradation around water-points under different management systems
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