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Evaluation of tumour-associated antigens to optically label cutaneous basal cell carcinoma for surgical excision
Published 2022“…The specific binding to EpCAM, EMA, CSPG4, and CD138 antigenexpressing cell lines was observed on incubation with scFvUBS54-SNAP-tag, scFvID405- SNAP-tag, 9.2.27scFv-SNAP-tag, and scFvh-STL002-SNAP-tag, respectively. In addition, we showed the selective cell killing effect of scFvUBS54-SNAP after conjugating it with the cytotoxic drug BG-modified auristatin-F (BG-AF). …”
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Pharmacokinetic-Pharmacogenetic-and-Pharmacodynamic Adherence Relationships in Cohort South African HIV Infected Children on Lopinavir-and Nevirapine-Based Regimens
Published 2019“…Lopinavir and nevirapine pharmacokinetics demonstrate considerable inter-individual variability, which may affect treatment outcomes. At least part of this variability may be explained by host genetic factors. …”
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The relationship between genes associated with the pain pathways and the development of chronic shoulder pain and disability in South African breast cancer survivors
Published 2025“…This thesis therefore sought to identify potential genetic contributors to variability in pain response and to understand the development of chronic pain and disability in SA BCS of mixed ancestry background. …”
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Flagellin glycosylation in Pantoea ananatis
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Subantarctic Indian Ocean microbial gene duplications and their role in biogeochemical cycling
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Molecular systematics of the genus Hypnea (Rhodophyta) in South Africa, with the description of a new genus, Tenebris (Cystocloniaceae, Rhodophyta)
Published 2018“…Sequences were assembled, aligned by eye, and analysed using maximum likelihood, Bayesian analyses, and genetic distance (GD) matrices for molecular analysis. …”
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The biogeography, systematics and conservation of Phreatoicidean isopods in South Africa
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Characterization of Ulva (Ulvaceae, Chlorophyta) species cultured in commercial abalone farms in South Africa, and comparison with closely related wild species, using morpho-anato...
Published 2022“…The genetic distance between the U. uncialis and farmed U. lacinulata samples were 0.16%, 0.76% and 0.92% for the markers, rbcL, ITS and tufA, respectively. …”
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The aetiology of pain in chronic midportion Achilles tendinopathy
Published 2022“…The presentation of chronic Achilles tendon pain is variable and therefore it is reasonable to propose that this variability may be influenced by a genetic component. …”
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Synthesis of polymer-bound small-molecule kinase inhibitors as anti-tumour agents
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Optimisation study of geographical allocation of solar PV generation capacity for grid support
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Metaheuristics for the selection and scheduling of jobs with time-dependent durations
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Delineation of the genotype and phenotype of children presenting with dystrophies, excluding dystrophinophathies, in the Western Cape of South Africa. (2019-2020)
Published 2022“…Background Muscular dystrophies (MD) and myopathies are a distinct group of clinically and genetically heterogeneous inherited muscle diseases. …”
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Seed source variation : assessment of potential for improving plantation forestry in Rwanda
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Native Fusarium species from indigenous fynbos soils of the Western Cape
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