Human immunodeficiency virus (HIV) and Human papillomavirus (HPV) infection and cell cycle regulators in preinvasive lesions and invasive carcinomas of the anus by De Jager, Louis Johann

“…There was a significant decrease in the proportion of pRb-positive cells from well to poorly differentiated squamous cell carcinomas (p=0.03). …”
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Identifying novel drugs for the treatment of rhabdomyosarcoma by Bleloch,Jenna

“…To investigate the anti-cancer activity of AJ-5 in RMS cells, MTT assays were firstly performed in ERMS and ARMS as well as 'normal' cells. …”
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An investigation into the P13-K/AKT signalling pathway in TNF-a-induced muscle proeolysis in L6 myotubes by Sishi, Balindiwe J. N.

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Molecular Characterisation of Diffuse Large B-cell Lymphoma in South Africa by Ramorola, Beatrice Relebogile

“…In silico analysis using the Cancer Genome Atlas (TCGA) database confirmed that SOCS1 is in the top 20 frequently mutated genes in DLBCL. …”
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Investigating the role of a FAM111B mutation in hereditary fibrosing poikiloderma (POIKTMP) using induced pluripotent stem cell (iPSC) model by Gumede, Dimakatso B

“…Future work will also explore the gain-of-function hypothesis to further understand the role of FAM111B in fibrosis and cancer phenotype in POIKTMP.…”
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Investigation of non-prostatic in vitro prostate-specific membrane antigen expression in MCF-7 and MDA-MB-231 breast tumour cells

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Haemostatic abnormalities in canine spirocercosis

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Expression and regulation of N-Myc Downstream- Regulated gene 1 in squamous cell carcinoma of the oesphagus by Bracher, Jacqueline Claire

“…Dysplastic tissue and poorly differentiated tumour tissue stained positively for NDRG1 in the plasma membrane, while moderately and well differentiated tumours displayed mixed staining for NDRG1 in the plasma membrane, cytoplasm and nucleus. …”
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Identification and characterisation of micrornas involved in the pathogenesis of HIV–associated non-Hodgkin's lymphoma by Goolam Hoosen, Taahira

“…South Africa has the world's largest antiretroviral therapy (ART) programme and as such, HIV infected people are living longer, and consequently the incidence of HIV co-morbidities has increased dramatically. HIV/AIDS defining cancers are such co-morbidities with Non- Hodgkin's lymphomas (NHL) being the second most common HIV-associated cancer. …”
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Structure-based drug discovery against a novel antimalarial drug target, S-adenosylmethionine decarboxylase/ornithine decarboxylase

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Cofactor of BRCA1 as a modulator of hepatocellular carcinoma growth and migration by El Zeneini, Eman Mahmoud

“…To elucidate the biological significance for this overexpression in HCC, RNA interference was used to silence the expression of COBRA1 in the well differentiated HCC cell line, HepG2. The silencing efficiency was confirmed by both reverse transcription-polymerase chain reaction (RT-PCR) and Western blot analysis. …”
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Molecular crosstalk between apoptosis and autophagy induced by a 2-methoxyestradiol analogue (C19) in HeLa cells

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Development and validation of an in vitro model of dendritic cell identification and activation by Clark, Anel

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A characterisation of genes involved in apoptosis resistance by Davis, Tanja Andrea

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The effect of combination treatment of vascular endothelial growth factor receptor 3 inhibitor, MAZ-51, and zingerone on melanoma cell proliferation

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HIV alters the expression of miRNA hsa-miR-200c-3p in B-cells, leading to enhanced migration of lymphoma cells by Ramorola, Beatrice Relebogile

“…Burkitt’s lymphoma (BL), a highly aggressive cancer, is one of the most common NHLs associated with HIV infection. …”
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Programmed cell death-ligand 1 (PD-L1) expression in HIV-associated diffuse large B-cell lymphoma – role and regulation by Latib, Zahra

“…This warrants a deeper exploration into the significance of PD-L1 overexpression, as well as the mechanisms influencing PD-L1 expression, in HIV-associated DLBCL. …”
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LncRNA discovery in the Listeria monocytogenes infection model by Magagula, Loretta Q

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Characterization of the interaction between acetylcholinesterase and laminin : a template for discovering redundancy by Swart, Chrisna

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