Phosphoglucomutase 1 (PGM1) expression and regulation in cancer cells by Maranyane, Hapiloe 'Mabaruti

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The metabolism and receptor interactions of C11-oxy steroids: implications for hormonal homeostasis and pathophysiology by Gent, Rachelle

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Characterization of the promoter region of the HAMP gene implicated in iron metabolism and its possible association with Oesophageal cancer in the black South African population by McGregor, Nathaniel Wade

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Novel treatment strategies for breast, lung and cervical cancer by Hamid, Mogammad Baahith

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A comparative analysis of the G1/S transition control in kinetic models of the eukaryotic cell cycle by Conradie, Riaan

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Towards understanding the metabolism of in vitro Sutherlandia frutescens (L.)R.Br. cultures by Colling, Janine

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Circadian rhythms as novel chemotherapeutic strategies for breast cancer by Mitchell, Megan Irvette

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Mutational analysis of the solute carrier family 11 member 1 gene (SLC11A1) implicated in iron transport by Zaahl, Monique G. (Monique Glenda)

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The role of a positive feedforward loop in regulating yeast glycolytic intermediate dynamics by Kotze, Sone

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Progestins and breast cancer : significance of progesterone receptor isoforms and their altered ratios by Cartwright, Meghan Carni

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Investigating a novel small molecule inhibitor of nuclear import as an anti-cancer approach by Chi, Ru-pin Alicia

“…An in silico screen for Kpnβ1 inhibitors identified several small molecules that showed inhibitory effects on nuclear import as well as cancer killing activity. In this study, we aimed to examine the potential of one such small molecule, the Inhibitor of Nuclear Import-43 (INI-43) as a lead compound with anti-cancer activities using multiple cancer models. …”
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The relationship between HIF-1α and autophagy activity in the hypoxic environment of breast cancer by Mills, Justin

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An Activity-Based Proteomics Approach for Identifying Ajoene's S-thiolation Protein Targets in Blood and Cancer Cells by Kusza, Daniel Andreas

“…Pathway analyses revealed that ajoene interacts with several targets involved in the control of cell cycles (G2/M cell cycle checkpoint), energy metabolism (glycolysis and pentose phosphate pathway) and the regulation of protein metabolism (translation, folding, quality control and degradation), which supports previously reported cytotoxic modes of action for ajoene against MDA-MB-231 cancer cells. …”
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Evaluation of the effect of radiofrequency electromagnetic waves on radiosensitivity by Chinhengo, Angela

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Potential anticancer actions of cholecalciferol on a cervical squamous carcinoma cell line

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Cofactor of BRCA1 as a modulator of hepatocellular carcinoma growth and migration by El Zeneini, Eman Mahmoud

“…As such, COBRA1 is able to regulate a substantial number of genes involved in a number of pathways, including cell cycle control, metabolism, cell proliferation and DNA repair. …”
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Translational profiling of adipocytes within adipose depots and intermuscular adipose tissues by Hassan, Sara Serag

“…Obesity is associated with wide array of medical disorders not only limited to cardiovascular diseases, but also extended to include immune disorders, as well as some types of cancer. Hence, there is an indispensible need for identifying new therapies for tackling this serious health burden. …”
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In vitro signal transduction mechanism exerted by 2-ethyl-3-O-sulphamoyl-estra-1,3,5(10),15-tetraen-3-ol-17-one in combination with dichloroacetic acid on breast adenocarcinoma (MC...

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Identification of biomarkers of tumour blood vessels for therapeutic targeting

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Investigation of vasculogenic mimicry in melanoma tissue

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