Progestins and breast cancer : significance of progesterone receptor isoforms and their altered ratios by Cartwright, Meghan Carni

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Chemoresistance in a breast cancer animal model: the role of obesity and inflammation by Mentoor, Ilze

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Mechanistic insights into the cancer cell cytotoxicity and blood stability of the garlic compound ajoene by Kusza, Daniel Andreas

“…The phenol ajoene analogues were found to be more cytotoxic against WHCO1 oesophageal cancer cell proliferation than the corresponding amides. …”
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Investigating the nuclear import protein KPn߀1 as a cancer therapeutic target by Ajayi-Smith, Aderonke Fopesaye

“…C60 treatment resulted in the inhibition of cancer cell proliferation, colony formation, migration and invasion. …”
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The regulation of the T-box transcription factor TBX3 in Luminal A breast cancer by Ncube, Stephanie Maria

“…This study shows that inhibiting the AKT pathway in MCF-7 and T47D breast cancer cells using a commercially available AKT inhibitor as well as a dominant negative AKT results in a decrease in TBX3 protein levels. …”
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A fructose transporter (GLUT 5) as a target for breast cancer therapy and imaging

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Evaluation of the cytotoxic effect of Salvia triloba on Osteosarcoma (U2OS) cell line by Abd El-bary, Rowan Bahaa El-din

“…Despite the huge advancement in the field of cancer treatment, the conventionally used treatments still present significant challenges such as low effectiveness and adverse side effects. …”
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Modulating the expression and activity of the nuclear import protein, Karyopherin β1, in cancer cells by Carden, Sarah

“…In this study, we investigated the biological effects associated with Kpnβ1 overexpression in order to further elucidate the relationship between Kpnβ1 and the cancer phenotype. Our data revealed that Kpnβ1 overexpression, above what was already detected in cancer cells, resulted in reduced proliferation and an associated delay in cell cycle progression. …”
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Cytotoxic Activity of Salvia Officinalis Extract Mediated by the Inhibition of JAK2 in Breast Cancer by Alawadi Dawood, Salma

“…Background: Breast cancer is the most common type of invasive cancer in women in their forties and fifties. …”
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Investigating a novel small molecule inhibitor of nuclear import as an anti-cancer approach by Chi, Ru-pin Alicia

“…Through culture-based in vitro assays, we demonstrated that INI-43 inhibited the proliferation of cancer cells grown anchorage-dependently and independently. …”
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Dynamic interactions between skeletal muscle and breast cancer cells following chemotherapeutic treatment by Conradie, Daleen

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The relationship between HIF-1α and autophagy activity in the hypoxic environment of breast cancer by Mills, Justin

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Characterization of a polypeptide factor that inhibits the growth of a human breast cancer line in vitro by Harris, Neil S

“…This thesis concerns a melanoma-derived growth regulatory factor that inhibited proliferation of several malignant human cell lines, and, in particular, a line designated UCT-BR-1, which was derived from a human breast cancer metastasis. …”
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Antiproliferative, anti-inflammatory and antioxidant activities of leaf extracts, fractions and isolated compounds from Ptaeroxylon obliquum

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Evaluation of the effect of radiofrequency electromagnetic waves on radiosensitivity by Chinhengo, Angela

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The modulation of various signal transduction pathways in colorectal carcinoma cells by docosahexaenoic acid by Du Toit, Joe-Lin

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Investigating the effects of progestins and adiposity on c-Jun N terminal kinase (JNK) signalling in breast cancer by Simons, Mishkah

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The effect of inhibiting KPNB1-mediated nuclear import on cancer cell biology and inflammatory transcription factor signalling by Stelma, Tamara

“…These changes in cancer cell biology when KPNB1 is inhibited may in part be due to its function as a nuclear transporter of transcription factors associated with cancer cell proliferation, migration and invasion. …”
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Potential anticancer actions of cholecalciferol on a cervical squamous carcinoma cell line

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In vitro influence of nutrient deprivation and papaverine exposure in MCF-7 and MDA-MB-231 breast cancer cell lines

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