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Interactions of GPR54 and GPR147 receptors with RF-amide ligands
Published 2014Get full text
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Anti-mycolic acid gallibodies as labelling tools in tuberculosis-related biological samples
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Characterising the anticancer effects of a small molecule with potential to inhibit nuclear import via karyopherin beta1
Published 2018“…Studies have shown the involvement of Karyopherin proteins in nuclear pore assembly, nuclear membrane assembly and DNA replication. Since all these cell regulatory functions are critical for normal cell function, dysregulation of Karyopherin proteins may have an impact on cancer cell survival. …”
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Immunochemistry of mycolic acid antigens in tuberculosis
Published 2013Get full text
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Identification of drug leads against HCV and malaria using different target proteins
Published 2014“…This led to the conclusion that the linkers’ lengths should be optimized so as to have a SHAL that fits properly in the desired binding sites. The HCV glycoprotein E2 has also been shown to play an essential role in hepatocyte invasion by binding to CD81 and other cell surface receptors. …”
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Towards paper-based micro bio-sensing of biomarker anti-mycolic acid antibodies for TB diagnosis
Published 2019Get full text
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Development of SNAP-tag based fusion proteins as novel auristatin F-containing immunoconjugates and photoimmunotheranostics in the detection and treatment of triple-negative breast...
Published 2022“…After showcasing the self-labeling potential of the SNAP-tag component, surface binding of the fluorescently labeled product was demonstrated on antigen-positive TNBC cell lines through confocal microscopy and flow cytometry. …”
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Evaluation of cellular interactions with functionalized scaffolds for cardiovascular tissue engineering
Published 2022“…The polymer samples were surface modified with 0, 40, and 80 % PAA. All samples were imaged using SEM prior to in vitro cell culture evaluation. …”
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Development and Characterization of a Modified Vaccinia Ankara Vaccine Candidate Expressing the SARS-CoV-2 Spike Glycoprotein
Published 2023“…The candidate vaccine induced good T-cell responses and binding antibodies, but not neutralizing antibodies. …”
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Identification and potential application of quorum quenching bacterial endophytes from South African medicinal plants
Published 2020Get full text
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Cloning and expression of a functionally active truncated N-glycosylated KSHV complement regulatory protein and immunohistochemical studies with the anti-KCP peptide antibody
Published 2017“…The KSHV open reading frame (ORF) 4 encodes a complement regulatory protein (Kaposi complement-binding protein, KCP) that binds complement proteins and inhibits the complement-mediated lysis of cells infected by the virus, thus providing a strategy for evasion of the host complement system. …”
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Anti-biofilm activity of the tick-derived antimicrobial peptide Os(11-22)NH2 against candida albicans ATCC 90028
Published 2025Get full text
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