Characterisation of two desiccation-linked dehydrins from Xerophyta humilis by Fan, Cynthia

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Regulation of desiccation tolerance in Xerophyta seedlings and leaves by Lyall, Rafe

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Plant production of Gonococcal peptide vaccine, candidate peptide display with HPVs by Lindsay, Sarah

“…These chimeric VLPs as well as HPV16 VLPs were expressed and successfully purified from plants and demonstrated self-assembly into VLPs. …”
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Biological control of a plant pathogen and pest by expression of a cloned Serratia marcescens chiA gene and Bacillus thuringiensis cryIA(c) gene in endophytic bacteria by Downing, Katrina Jo

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Biomolecular condensation of intrinsically disordered regions in P. falciparum and H. sapiens transcription factors by Karamanof, Leonidas Marthinus

“…This work demonstrates that the PfRPB1-CTD, as well as a panel of GTF-IDR fusion proteins, including P. falciparum (Pf) and Homo sapiens (Hs) TATA-binding protein-IDR (TBP), TFIIAαß-IDR and TFIIFß-IDR can drive biomolecular condensation in vitro. …”
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The functional characterisation of the XhABFA transcription factor from the resurrection plant Xerophyta humilis by Proctor, Jessica Diane

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The c-Myc/TBX3/nucleolin/Hsc70 signalling axis in breast cancer by Ncube, Stephanie Maria

“…This project therefore aimed to (1) identify signalling molecules that upregulate TBX3 expression in MCF-7 breast cancer cells as well as (2) identify and characterize protein partners that cooperate with TBX3 to drive its oncogenic functions in these cells. …”
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Receptor concentration affects glucocorticoid action by Robertson, Steven Ernest

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Modelling the glucocorticoid receptor dimerisation cycle by Barry, Christopher James

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Investigating the role of nuclear transport proteins secreted by cancer cells by Whitehouse, Alexandra

“…These cargo proteins, if any, may also affect the biology of cells targeted by conditioned media treatments. In this study, we thus investigated Kpnb1 binding partners in the secretome of cancer cell lines. …”
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Molecular interactions mediated by the surface antigen CD5 during T lymphocyte activation by Broszeit, Richard

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Investigating grape berry cell wall deconstruction by hydrolytic enzymes by Zietsman, (Anscha) Johanna Jacoba

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Using fluorescene to understand Mycobacterial Heterogeneity at a Single Cell Level by Parbhoo, Trisha

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The influence of cell wall bound calcium, cell number and size on the development of mealiness in 'Forelle' pear. Evaluation of X-ray CT and NIR as non-destructive techniques for m... by Muziri, Tavagwisa

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Mechanistic insights into the cancer cell cytotoxicity and blood stability of the garlic compound ajoene by Kusza, Daniel Andreas

“…This thesis reports on the synthesis of eight ajoene analogues designed to probe structure-activity relations into cancer cell cytotoxicity and blood stability. Structural variations included introduction of different solubility enhancing terminal groups (amide and phenol) as well as variations in the sulfoxide / vinyl-disulfide core. …”
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Comparison between endocytosis and intracanalicular sequestration of cell-surface antigens in human platelets by Jennings, Brent

“…When antibodies, specific for platelet cell-surface receptors, bind to platelets they may either undergo endocytosis into intracellular vacuoles, or may merely become sequestered within the canalicular system of platelets. …”
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Characterising the magnitude and breadth of T cell responses to SARS-CoV-2 vaccination by Chauke, Valencia Masego

“…The magnitude of T cell responses to full spike was examined, as well as crude T cell breadth, using 7 peptide pools spanning the entire length of the spike protein at BL and 4 weeks (W4) post-vaccination. …”
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GnRH and neuropeptide regulation of gonadotropin secretion from cultured human pituitary cells by Wormald, Patricia J

“…This thesis has therefore investigated the binding characteristics of the human GnRH receptor, in comparison to those of the rat receptor, as well as the activities of a number of GnRH analogues for stimulating luteinising hormone (LH) and follicle stimulating hormone (FSH) secretion from cultured human pituitary cells. …”
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