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Investigation of mycobacterial cell wall genes and their requirement for survival in immune related stressful conditions
Published 2021“…Growth defects in this condition were characterized by short and bulgy cells, as well as elongated filamentous cells with visible chaining. …”
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Modulating the expression and activity of the nuclear import protein, Karyopherin β1, in cancer cells
Published 2017“…Inducible expression of Kpnβ1-EGFP, as well as the treatment of cells with the small molecule inhibitor INI-43, were used as mechanisms of dysregulation. …”
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Potential radiosensitization of breast- and lung cancer cells by a novel antimitotic oestrogen analogue
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Parameters involved in the enzymatic deconstruction of the Wine Grape cell wall matrix during winemaking
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Pro-apoptotic and radiosensitizing potential of four candidate microtubule regulators in breast cancer cells
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Evaluating the neuroprotective effect of curcumin on a PINK1 cell model of Parkinson's disease
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Evaluation of the neurotoxicity of pentachlorophenol and its active metabolites on SH-SY5Y neuroblastoma cells
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Evaluation of tumour-associated antigens to optically label cutaneous basal cell carcinoma for surgical excision
Published 2022“…Our aim was to identify BCC-specific cell surface proteins and design, engineer, and test a range of SNAPtag–based antibody fusion proteins that would specifically bind to and detect such BCC cell surface receptors. …”
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Mechanism of Action Studies of Phenotypic Whole-cell Active Antimalarial Leads Through Target Identification
Published 2023“…Here, drug-labelled matrices were used to capture protein binding partners of KP68 and KP124 from P. falciparum cell lysates. …”
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Generating a proteomic profile of neurogenesis, through the use of human foetal neural stem cells
Published 2020“…Whereas NS cells are more developmentally defined, express multiple membrane proteins, have activated focal adhesion, thereby increasing their binding and interaction with their environment. …”
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Functional characterization of cell wall-related proteins of unknown function (CW-PUFs) in Arabidopsis thaliana
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The effect of acute phase proteins on hepatic insulin signalling
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Cell wall compositional differences between mealy and non-mealy ‘Forelle’ pear (Pyrus communis L.)
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The effect of inhibiting KPNB1-mediated nuclear import on cancer cell biology and inflammatory transcription factor signalling
Published 2018“…Electromobility shift assays confirmed a reduced NFkB binding to an NFkB DNA-binding sequence in the nuclear extract of KPNB1-inhibited cells. …”
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Hybrid hydrogels based on RAFT mediated poly(N-vinyl pyrrolidone)
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Synergistic cytotoxicity of Solanum aculeastrum with 4-hydroxytamoxifen in the MCF-7/TAMR-1 breast adenocarcinoma cell line
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The Antiatherogenic Potential of Two triterpenes from Protorhus longifolia stem bark (Benrh.) Engl.
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