An investigation of the clinical profile and extent of Long QT Syndrome (LQTS) associated with the KCNQ1-A341V mutation in South Africa and with the KCNH2-A1116V mutation in an Ita... by Crotti, Lia

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HPV pseudovirion production in plants by Kennedy, Paul

“…Human papilloma virus (HPV) infection is the most common etiological agent of cervical cancer, the most common cancer in women in Africa. …”
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Optimization and characterisation of plant produced Human Papillomavirus pseudovirions in Nicotiana benthamiana by Adams, Ayesha

“…Human papillomavirus (HPV) is known to be the cause of anogenital and oropharyngeal cancers as well as genital and common warts. There are currently three prophylactic virus-like particle (VLP) based vaccines. …”
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Towards the development of plant-made PsVs as potential delivery vehicles for therapeutic HPV vaccines by Edwards, Amy

“…These constructs were co-expressed in N. benthamiana with expression vectors encoding BPV-1 or HPV-35 L1 and L2 proteins. …”
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Investigation of molecular regulatory control of the cardiac-enrich acetyl-CoA carboxlase by Manga, Nayna

“…Collective data gathered from studies of different forms of heart disease indicate a common denominator among them, namely a detrimental change in energy homeostasis. …”
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Joernalistieke privilegie: ‘n Kritiese analise van ‘n joernalis se regsplig om vertroulike bronne van bekend te maak met besondere verwysing na die reg op vryheid van uitdrukking (...

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A comparison of hunter-gatherer material culture from Matjes River Rock Shelter and Nelson Bay Cave by Ludwig, Ben

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The isolation, purification, tissue localization and identification of a glycoprotein found in the crude mucus gel of patients with carcinoma of the stomach by Nthato, Chirwa

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The Immunogenicity of Plant-produced Human Papillomavirus (HPV) Virus-like particles (VLPs) in Mice by Naupu, Paulina Ndinelago

“…Firstly, the L1 proteins of the 8 most common high-risk Human papillomavirus types in Africa (HPV 16, 18, 31, 33, 35, 45, 52, and 58) and 2 low risk types (HPV 6 and 34) were transiently expressed in Nicotiana benthamiana. …”
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New distinctions : the impact of class and race on the cultural preferences of youth in Cape Town and Belo Horizonte by Schenk, Jan-Christof

“…Due to global cultural flows these processes do not remain purely local phenomena but they find expression in localised forms as common structures of difference around the globe, thus structurally undermining local efforts to build a non-racial, non-classist society. …”
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Molecular characterization of a porcine picobirnavirus RNA-dependent RNA polymerase

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Impact of Intracellular Glutathione Depletion on Neutral Sphingomyelinase in Human Hepatoma HepG2 cells by Tanios, Marie

“…In addition, results show that nSMase 1 and 3 expressions were upregulated, while nSMase 2 was not expressed in HepG2 cells. …”
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Investigation of HIV-TB co-infection through analysis of the potential impact of host genetic variation on host-pathogen protein interactions by Heekes, Alexa Storme

“…Finally, we identified common and consequential variants within prioritised proteins that may be clinically-associated with HIV and TB. …”
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Cysteinyl leukotriene receptor 1 as a host determinant for susceptibility to cutaneous leishmaniasis in a mouse model by Cele, Zama

“…In male and female BALB/c mice homozygous deficient for CysLTR1, we found that disease progression, parasite burdens, antibody and cytokine responses showed no significant alteration when compared to control animals with normal CysLTR1 expression. Importantly, expression of CysLTR2 did not appear to compensate for lack of CysLTR1 in CysLTR1-/- mice. …”
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The intersection between the Islamic law of inheritance and the South African law of succession by Essop, Fatima

“…In this regard, the thesis recommends that our courts should develop the common law to give expression to a Muslim testator's freedom of testation to devolve his or her estate in accordance with the constitutional guarantees of freedom of religion (s15) and right to property (s25). …”
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The administration of a university with particular reference to the University of Cape Town by deVries, Peter

“…The early stadia were not created but grew as the natural expression of the spiritual, intellectual and social energies of the age - fundamentally they were meeting places of students and masters drawn together by a common desire for learning.…”
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Immunogenic assessment of plant-produced Human papillomavirus type 16 chimaeric L1:L2 virus-like particles and the production of an encapsidated therapeutic DNA vaccine candidate by Chabeda, Eva Aleyo

“…Cervical cancer caused by infection with Human papillomavirus (HPV) is the 4th most common cancer in women globally, and results in an estimated 266 000 deaths every year. …”
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Chlamydia trachomatis diversity and pathogenesis in young South African women, related to HPV prevalence and risk by Kanyoka, Pride

“…No significant differences in cervical CD4+ T cell activation or CCR5 expression was evident between CT-infected and uninfected AGYW, although both markers were generally expressed at high frequencies. …”
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