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Studies on sand fly resting habitats, plant feeding patterns and volatilome in a leishmaniasis endemic area of Kenya
Published 2021Get full text
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Investigating the relationship between miRNA expression and epithelial mesenchymal transition in colorectal cancer
Published 2017“…Therefore, both EMT and stem cell phenotypes have been implicated in carcinogenesis and metastasis of tumour cells. …”
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Regulation of the anti-senescence factor, TBX2, by the UV stress signalling pathway and the mitotic cyclin dependent kinases
Published 2017“…Several lines of evidence have also implicated members of the T-box gene family in cell cycle regulation and in cancer. …”
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Identifying novel drugs for the treatment of rhabdomyosarcoma
Published 2022“…Western blotting revealed that AJ-5 induced levels of key DNA damage response proteins (γH2AX, p-ATM and p-Chk2) and the p38/MAPK stress pathway. …”
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Regulation of the anti-senescence factor, TBX2, by the UV stress signaling pathway and the mitotic cyclin dependent kinases
Published 2024“…Several lines of evidence have also implicated members of the T-box gene family in cell cycle regulation and in cancer. …”
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The chromatin landscape of colorectal cancer cells
Published 2021“…As CTCF binding at CBSs sites is highly modular, the use of targeted CRISPR-mediated gene-editing and DNA methylation at PA-LCe CBSs may represent viable and druggable oncogenic targets.…”
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Whole-exome sequencing of cases with familial cardiomyopathy
Published 2021“…As heterogeneous disorders, over 50 genes have been implicated in these cardiomyopathies to date. However, the yield of genetic testing ranges from less than 40% in idiopathic DCM to over 50% in ACM and HCM, indicating that many causal genes are yet to be identified. …”
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Investigation of molecular regulatory control of the cardiac-enrich acetyl-CoA carboxlase
Published 2024“…In order to further investigate ACCj3 transcriptional regulation, we isolated a 947 bp fragment in the 5'-flanking region of the rat ACCj3 gene. 5'-Rapid amplification of cDNA ends (5'-RACE) analyses showed that this fragment did not contain the known ACCj3 gene promoter. …”
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Potential anticancer actions of cholecalciferol on a cervical squamous carcinoma cell line
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Circadian rhythms as novel chemotherapeutic strategies for breast cancer
Published 2015Get full text
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The role of the intestinal immune system in the development and treatment of type 2 diabetes
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Determination of the mechanism of synergy of SQ109 with rifampicin and isoniazid in Mycobacterium smegmatis
Published 2015Get full text
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Investigation of Neurexin 2 as a candidate for Parkinson's Disease
Published 2022Get full text
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