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Autism Spectrum Disorder and Mitochondrial Dysfunction: The Role of Mitochondrial Dynamics
Published 2023“…Numerous genes and biological pathways are implicated in the aetiology of the neurodevelopmental disorder, autism spectrum disorder (ASD). …”
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Genetic analysis of inherited retinal diseases in indigenous Southern African populations
Published 2017“…Whole exome sequencing (WES) was performed on genomic DNA samples from 56 individuals from 16 families. …”
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Characterisation of two aphid picorna-like viruses
Published 2017“…No nucleic acid homology was detected between ALPV cDNA and CrPV by dot-blot hybridization. ALPV is serologically unrelated to seven other insect picornalike viruses. …”
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The trafficking of the Mycobacterium tuberculosis PE and PPE proteins
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Genetic studies for sustainable aquaculture of the sea urchin, Tripneustes gratilla
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The biological bases of social deficits: the roles of social motivation, theory of mind, and selected genotypes (OPRM1, 5-HTTLPR) in autism spectrum disorder
Published 2021“…This approach can be supported by focusing on established, well supported psychological theories, and selected ASD candidate genes that could be implicated in these theories, and ideally the genetic mechanism implicated should be one that can be targeted by existing medications. …”
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An outcomes evaluation of the Zim-TTECH cervical cancer intervention in Harare Metropolitan Province, Zimbabwe
Published 2023“…The programme has also been keeping in tandem with technological evolutions including the adoption of thermoablative techniques and planning for the rolling out of highly sensitive human papilloma virus (HPV) DNA testing in line with Ministry of Health strategies and WHO guidelines. …”
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Molecular systematic study of Southern African Oxalis (Oxalidaceae)
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The influence of small RNAs on the physiology of Mycobacterium tuberculosis
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Investigation of minor groove binders (MGB), non-ionic surfactant vesicles (NIV) delivery systems and IL-4i1 as novel pathogen- and host-directed drug therapy for tuberculosis
Published 2020“…We screened the anti-mycobacterial activity of 172 minor groove binder (MGB) compounds that selectively bind to AT-rich regions of the minor groove of bacterial DNA with the helical structure matching that of DNA in Mtb culture. …”
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Environmental and Biosafety Research Ethics Committees: Guidelines and Principles for Ethics Reviewers in the South African Context
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Working towards a plant-produced Bovine papillomavirus vaccine: expression of BPV1 virus-like particles and pseudovirions in Nicotiana benthamiana
Published 2023“…Bovine papillomaviruses (BPVs) are DNA viruses implicated in several diseases and cancers of considerable veterinary and agricultural importance in cattle, horses, as well as several wild animal species, leading to their economic depreciation through the deterioration of their function and appearance. …”
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Investigations of the molecular determinants of maize streak virus replication
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Characterisation of dysregulated proteins in macrophages infected with Mycobacterium smegmatis focusing on matrix metalloproteases and their effectors
Published 2019“…Intercellular communication is hypothesised to be delivered to neighbouring cells through exosomes carrying DNA, RNA, proteins and DNA/RNA binding proteins, and via signalling scaffolds formed by the 14-3-3 proteins amongst others. …”
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Mycobacterium tuberculosis : genetic and phenotypic comparison
Published 2012Get full text
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