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Investigating a novel small molecule inhibitor of nuclear import as an anti-cancer approach
Published 2017“…Recently, research in our own laboratory and others have reported elevated expression of the nuclear transporter Kpnβ1 in multiple cancers. …”
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Development of microalgae as a biopharming platform
Published 2022“…These initial results showed promise and points to a system that requires optimisation for increased transfection rates and protein expression. …”
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Breaking Down Defenses: Autophagy as a Therapeutic Tool to Enhance Chemosensitivity in Neuroblastoma
Published 2025“…Furthermore, Bafilomycin A1 pretreatment downregulated mRNA expression of pivotal genes such as ATG7, implying that inhibiting autophagic flux sensitizes neuroblastoma cells to Cisplatin. …”
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Exploring miR-142-3p in cervical cancer: Implications for treatment response
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Potential anticancer actions of cholecalciferol on a cervical squamous carcinoma cell line
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Exploring the potential for biomarkers to aid forensic diagnosis of traumatic brain injury (TBI) – a systematic literature review and meta-analysis
Published 2025“…A wide range of biomarker expression levels were noted across all articles (from 0.01 to 1.5 million pg/mL). …”
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Occurrence of haemoparasites in donkeys in Central Zone, Tanzania
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Target indicators and mechanistic function of epidrugs with activity against multiple stages of Plasmodium falciparum parasites
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Bioactive Saussurea costus PCL–Gelatin Nanofibers: A Novel Nanoplatform for Enhanced Wound Healing
Published 2026“…These findings position 6% Sc-loaded PCL–GL nanofibers as a promising, mechanism-informed dressing that unites barrier protection, antibacterial and antioxidant functions, and pro-healing signaling into a single, biocompatible platform. …”
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Development and Characterization of recombinant immunotoxins for cervical carcinoma
Published 2024“…Immunotoxins have proven to be a promising alternative to current treatment for cancer. …”
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Inter-cell interference coordination in 5G ultra-dense networks
Published 2021“…This work further investigates non-orthogonal multiple access (NOMA) technique as promising solution to improve spectral efficiency and reduce interference in 5G Ultra Dense Network (UDN). …”
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Antidiabetic activity of Schkuhria pinnata – Biological screening, PK analysis and mode of action
Published 2021“…Messenger RNA and protein studies on C2C12 muscle cells revealed that the aqueous freeze dried extract and compound 1 enhanced insulin receptor, GLUT-4, glycogen synthase, pyruvate kinase and pyruvate carboxylase expression, suggestive of an insulin mimetic mode of action, while the butanone/pentane extract enhanced adenosine monophosphate-activated kinase (AMPK) protein expression by a non-insulin dependent mechanism. …”
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The role of TBX2 and the anti-cancer activity of chromomycin A5 in pancreatic ductal adenocarcinoma
Published 2025“…Initial screening for TBX2 expression over four PDAC cell lines identified SW1990 cells as high TBX2-expressing cells suitable for the functional studies. …”
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