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Establishing in vitro models of neuroinflammation to investigate neuroimmune responses in neurocysticercosis
Published 2024“…This thesis's final aim was to set up a comparable translational in vitro human model of neuroinflammation using human II acute and organotypic brain slice cultures (hOBSCs). …”
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Evaluation of gamete dysfunction as a cause of failed human in vitro fertilization
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Exploring the effects of polymorphic variation on the stability and function of human cytochrome P450 enzymes in silico and in vitro
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NMR Metabonomics in an in vitro Model of HIV-1 latency
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In vitro bioassays as tools for evaluating toxicity of acidic drainage from a coal mine in Mpumalanga, South Africa
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Investigating permeation of anti-mycobacterial agents in Mycobacterium tuberculosis and M. tuberculosis-infected macrophages in vitro as a model for early stage tuberculosis drug d...
Published 2021“…The highly lipophilic natural product, fusidic acid (FA), its known human metabolite, 3-ketofusidic (3-ketoFA or GKFA37), and two C-3 alkyl esters (GKFA16 and GKFA17) as FA prodrugs were utilized in the study. …”
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Characterisation and consequences of urban water resilience at the human-mycobiota interface: risk versus reward
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Manipulation of the autophagic pathway sensitises cervical cancer cells to cisplatin treatment
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The effect of exogenous fibrolytic enzymes on fibre digestion in ruminant animals
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Anthracycline-induced cardiotoxicity : the role of proteolytic pathways
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Fibroblast growth factors, A potential game plan for regeneration of skeletal muscle
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Proteomic studies on patient responses to chemotherapy, radiotherapy and immunotherapy in cancers
Published 2016“…We carried out a retrospective serological study of primary and secondary autoimmune responses of various cohorts of cancer patients prior to and/or following a variety of distinct treatments (chemotherapy, radiotherapy and immunotherapy), using a large number of archived human serum samples. Our goals were to develop and validate a novel cancer-testis and -associated antigen microarray platform and to then explore its utility and general applicability in the cancer immunology field. …”
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