Anti-cancer effects of aqueous extracts of Dodonaea Viscosa on Burkitt lymphoma by Saferdien, Aaliyah

“…One TM commonly used by communities in the Western Cape regions of South Africa is derived from the plant Dodonaea viscosa. …”
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Next-Generation version of pseudomonas exotoxin a based immunotoxins with reduced immunogenicity for triple negative breast cancer (TNBC) treatment by Mthethwa, Jabulisile

“…Breast cancer continues to have the highest mortality rate in comparison to other cancer types, with approximately 19.4 million women aged 15 years and older living at risk of being diagnosed with breast cancer in South Africa. Triple-negative breast cancer (TNBC) subtype, which is mainly characterized by a lack of expression of the oestrogen receptor (ER), progesterone receptor (PR) and human epidermal growth factor receptor 2 (HER2), patients do not benefit from current standard treatments since they are based on these absent biomarkers leading to off-targets which results to an adverse side effects in TNBC patients. …”
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Clinico-pathological characteristics and outcomes of nephrology adolescents and young adults in Cape Town: a single centre study by Barday, Zibya

“…This study evaluates kidney outcomes, survival and challenges faced by AYA in a South African setting. Methods This 5-year retrospective study included AYA [aged 10-24] with chronic kidney disease, at a tertiary nephrology service in South Africa. …”
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Assessment of the effectiveness of electronic gatekeeping as a utilization management tool at Groote Schuur Hospital by Bosman, Michelle

“…It is relatively easy to implement and manage, and when combined with additional tools has the potential to result in larger reductions of unnecessary tests, cost savings and improved patient outcome.…”
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The effectiveness of graded motor imagery for reducing phantom limb pain and disability in amputees by Limakatso, Katleho Maxwell

“…Methods A single blinded randomised controlled trial was conducted at Somerset, Khayelitsha and Victoria hospitals in Cape Town, South Africa. The experimental group underwent a 6-week GMI programme where each phase was carried out for two weeks, during which the patient received treatment for 30 minutes on two separate days of the first week (at least one day apart) and continued with a structured home-exercise programme during the first week until the end of the second week. …”
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The effect of involving the private practioners on the quality of antenatal care of the indigent population of Tembisa

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Investigation of vasculogenic mimicry in melanoma tissue

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Predicting clinicians’ intentions towards the electronic health record (EHR) : an extended UTAUT model

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Epidemiology, diagnosis and aspects of treatment in persons with serious mental illness and co-occurring substance use disorders by Temmingh, Hendrik

“…Conclusion: In the context of a dearth of research into dual diagnosis in LAMIC countries such as South Africa, this thesis contains a large-scale epidemiological investigation into substance use comorbidity in patients with schizophrenia and other psychotic disorders. …”
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Paediatric procedural sedation and analgesia in the emergency centre: a description of the fasting status by Dunn, Cornelle

“…Safe, timely PSA with minimal pain and unnecessary suffering can become the norm in Emergency Medicine practice in South Africa.…”
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The therapeutic alliance as a component of risk management and assessment in forensic mental health by Swart Barbour, Tania

“…Background: Few forensic mental health facilities in South Africa use formal risk assessment instruments to monitor risk and recovery of forensic state patients. …”
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Estimating measurement error in blood pressure, using structural equations modelling by Kepe, Lulama Patrick

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Aqueous extracts of Dodonaea viscosa induce potent and selective cytotoxicity in DLBCL cells by Yekelo, Babalwa

“…Cancer is a major cause of death globally, with approximately 10 million deaths in 2020. In South Africa, the number of new cancer cases is expected to double by 2030. …”
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Whole-exome sequencing of cases with familial cardiomyopathy by Spracklen, Timothy

“…Results: In three families, genotype-phenotype correlations were identified that have not yet been reported in South Africa, although this genetic overlap between cardiomyopathies has been described elsewhere. …”
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Ideal characteristics of a listening device by Chappel, Alexia

“…Flyers (Appendix A, B, C & D) were sent out to companies and put-up all- over South Africa (Appendix E) (coffee shops and businesses). …”
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An investigation towards a conjugate vaccine against Streptococcus pneumoniae serotype 19A by Trimmel, Astrid Joan

“…Serotype 19A, not included in PCV7 as the structurally similar serotype 19F was assumed to crossprotect against 19A disease, emerged as the most prevalent serotype in several studies with significant presence in Sub-Saharan Africa and South-East Asia and is associated with multidrug resistance. …”
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Improving chronic disease monitoring in resource limited settings: simulation and economic evaluation approaches by Mukonda, Elton

“…The analytical study then utilised individual-level data on adults living with T2D in the Western and Northern Cape, South Africa to examine the relationship between adherence to current HbA1c monitoring guidelines and the achievement of glycaemic control targets, as well as longitudinal changes in HbA1c. …”
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Dosimetric comparison between 2D and 3D planned intracavitary brachytherapy for cervical cancer at Groote Schuur Hospital by Botha, Elaine

“…Traditionally, two-dimensional (2D) treatment planning using orthogonal radiographs has been employed in many low- and middle-income countries (LMICs), including at Groote Schuur Hospital (GSH) in Cape Town, South Africa. While standard 2D-based planning has historically been sufficient, it presents limitations in accurately estimating the dose to organs at risk (OARs) and the clinical target volume (CTV). …”
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miRNA signature of healthy vs impaired mesenchymal stem cells as a biomarker for autologous stem cell therapy by Seboko, Ascentia Mathapelo

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Treatment of HIV associated neurocognitive disorders by Decloedt, Eric Hermann

“…Africans are the most genetically diverse population worldwide and South Africa has the world’s largest ART programme, with most of patients currently receiving efavirenz-tenofovir-emtricitabine. …”
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