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The effects of the synthetic strigolactone GR24 on Arabidopsis thaliana callus culture
Published 2012Get full text
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A study of the molecular mechanism of progestin-induced regulation of IL-12 and IL-10 and implications for HIV pathogenesis
Published 2013Get full text
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An Activity-Based Proteomics Approach for Identifying Ajoene's S-thiolation Protein Targets in Blood and Cancer Cells
Published 2022“…Subsequent biological validation studies confirmed that the probe retained cytotoxicity against cancer cell lines in vitro (human epithelial mammary gland adenocarcinoma cancer cells (MDA-MB-231) and WHCO1) and shared the same compound–target interaction as its parent ajoene; namely, the regioselective S-thiolation of cellular proteins. …”
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Tuberculosis, Anaemia and Erythropoietin: a study evaluating the role of erythropoietin in the pathophysiology of the anaemia of tuberculosis
Published 2021“…It can be postulated, therefore, that TNFa may disrupt the interaction of transcription factors with critical sites of oxygen sensing on the enhancer and prevent the increased production of Epo. …”
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Characterisation of cardiac protein changes post death: pilot study
Published 2025“…Furthermore, it is through interaction of proteins with other micro molecules that crucial signalling pathways and cellular processes are functional and often drive mechanisms leading to healthy and disease of organism, as a result these changes can be studied to gain insight into disease pathophysiology. …”
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Involvement of endothelial cells and macrophages in mycobacterial infections
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Modelling human immune response dynamics to Mycobacterium Tuberculosis infection.
Published 2017Get full text
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Morphological, ethological and genomic discrimination of functional stocks of spotted grunter, an estuarine-dependent fish
Published 2025“…Individuals from the less -turbid Breede Estuary produced longer, louder sounds of a lower frequency; this is presumed to be due to differences in each estuary's ambient noise or due to spotted grunter communication behaviour whereby acoustic signals may only succeed visual signals. The divergence of phenotypic stocks can eventually alter the genomic structure of a species. …”
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The effects of prenatal and early-postnatal ethanol exposure on rat brain neurochemistry and behaviour
Published 2023“…Therefore, the research reported in this thesis describes ethanol-induced changes in neuroplasticity-related proteins, with specific reference to the extracellular signal-regulated kinase1/2 (ERK1/2) and glycogen synthase kinase-3-beta (GSK3β) signalling cascades, using two different animal models of FASD. …”
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Investigation of the effect of ocean acidification on the haemocyte proteome of the South African abalone, Haliotis midae
Published 2022“…This revealed a multifaceted interplay of various biological processes and signaling pathways in H. midae, such as the induction of anaerobic metabolism, cytoskeletal stabilization and the induction of the ERK/MAPK signaling cascade. …”
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Generalized time-frequency representations and their application to quantum control
Published 2015Get full text
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Electrospun carbon nanotube filled composite nanofibers by non-covalent compatibilization
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The Northern Cape frontier zone, 1700 - c.1815
Published 2016“…It describes and analyses the interactions which occurred between the principal peoples of this spatio-temporal area as the Cape colony expanded into the arid heartland of South Africa. …”
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The regulation of luteinizing hormone exocytosis in α-toxin permeabilized sheep anterior pituitary cells
Published 2017“…Since previous studies have shown that GnRH activates PKC and stimulates a rise in cytosolic [Ca²⁺]free, these results suggest that a synergistic interaction of the cAMP, PKC and Ca²⁺ second messenger systems is of importance in the mechanism of GnRH-stimulated LH exocytosis. …”
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