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Metallophiles as sources of antimycobacterial agents by Nyambo, Kudakwashe
Published 2023Get full text
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Page will reload when a filter is selected or excluded.- Nigeria 11 results 11
- Utilization 7 results 7
- Knowledge 5 results 5
- Utilisation 4 results 4
- Awareness 3 results 3
- General 3 results 3
- Geriatrics 3 results 3
- Medications 3 results 3
- Orthostatic drugs 3 results 3
- Adoption 2 results 2
- Background Falls are a major cause of morbidity and hospitalization in older people. Many drugs have been shown to increase the risk of falls in this population. Few empirical data exist on the use of fall-risk-increasing drugs among older people of sub-Saharan Africa countries. Objective This study aimed to assess the prevalence and predictors of falls, and the association between FRIDs, drugs causing orthostatic hypotension and falls. Setting Geriatric center, University College Hospital, Ibadan, Nigeria. Methods A cross-sectional study of 400 older patients aged ≥ 60 years selected consecutively at the geriatric centre, between September and November 2019, were interviewed using a semi-structured questionnaire. Socio-demographic information, medication utilization, and history of falls were obtained. Bivariate and multivariate analyses were carried out using SPSS 23. Alpha was set at 0.05. Main outcome measure Prevalence and predictors of falls among ambulatory older patients. Results The mean age of the older patients was 72.4 ± 7.3 years and 255 (63.7%) were females. The total number of FRIDs and ODs used by older patients was 578 (35.2%). The prevalence of fall was 181 (45.3%) which was signifcantly higher among the females compared with the males (51.8% vs 33.8%) p = 0.01. Classes of medications such as anti-Parkinson’s (p = 0.027), sedatives (p = 0.033), antipsychotics (p = 0.011) and anticholinergic (p = 0.027) were signifcantly associated with fall. Predictive factors for falls on logistic regression were female [OR = 2.375; 95% CI 0.274–3.704, p = 0.001] and use of antipsychotics [OR = 5.132; 95% CI 1.352–19.480, p = 0.016]. Conclusion The prevalence of falls was high and being a woman ≥ 60 years is a major risk factor for falling. Interventions to decrease falls in older patients by drug modifcation and deprescribing of FRIDs and ODs might reduce fall-related injuries. Thus, a multidisciplinary approach is essential for intervention to reduce the risk of falls and improve therapeutic outcomes among older patients. 2 results 2
- Background Falls are a major cause of morbidity and hospitalization in older people. Many drugs have been shown to increase the risk of falls in this population. Few empirical data exist on the use of fall-risk-increasing drugs among older people of sub-Saharan Africa countries. Objective This study aimed to assess the prevalence and predictors of falls, and the association between FRIDs, drugs causing orthostatic hypotension and falls. Setting Geriatric center, University College Hospital, Ibadan, Nigeria. Methods A cross-sectional study of 400 older patients aged ≥ 60 years selected consecutively at the geriatric centre, between September and November 2019, were interviewed using a semi-structured questionnaire. Socio-demographic information, medication utilization, and history of falls were obtained. Bivariate and multivariate analyses were carried out using SPSS 23. Alpha was set at 0.05. Main outcome measure Prevalence and predictors of falls among ambulatory older patients. Results The mean age of the older patients was 72.4 ± 7.3 years and 255 (63.7%) were females. The total number of FRIDs and ODs used by older patients was 578 (35.2%). The prevalence of fall was 181 (45.3%) which was significantly higher among the females compared with the males (51.8% vs 33.8%) p = 0.01. Classes of medications such as anti-Parkinson’s (p = 0.027), sedatives (p = 0.033), antipsychotics (p = 0.011) and anticholinergic (p = 0.027) were significantly associated with fall. Predictive factors for falls on logistic regression were female [OR = 2.375; 95% CI 0.274–3.704, p = 0.001] and use of antipsychotics [OR = 5.132; 95% CI 1.352–19.480, p = 0.016]. Conclusion The prevalence of falls was high and being a woman ≥ 60 years is a major risk factor for falling. Interventions to decrease falls in older patients by drug modification and deprescribing of FRIDs and ODs might reduce fall-related injuries. Thus, a multidisciplinary approach is essential for intervention to reduce the risk of falls and improve therapeutic outcomes among older patients. 2 results 2
- Cervical Cancer 2 results 2
- Cervical Cancer Screening 2 results 2
- Cervical cancer is a major reproductive health problem among women in Nigeria, every woman who has ever been sexually active is at risk. Certain factors also increase the risk of developing the disease. Cervical cancer can usually be found early by having regular Pap smear tests but this test is rarely provided and hardly utilised by women. This study was aimed at finding out the level of awareness of female health workers and the level of utilization of pap smear testing. The study was carried out using descriptive survey research design and the total population of 623 health workers in government owned hospitals were used as respondents for the study. Only 502 of the structured questionnaire were returned. Reliability of the instrument was determined using a test-retest method with Pearson Product Moment correlation and it yielded reliability co-efficient of 0.73. Data collected was analysed using descriptive statistics of frequency count and percentage for the research question, while inferential statistics of chi-square and regression were used to determine the level and the direction of relationship between the independent and the dependent. The level of significance was set at p-value <0.05. The results shows that only 118 (23.5%) have had pap smear test while 384 (76.5%) have not. Also, awareness of cervical cancer risk factors was significant (X2cal 33.426, X2crit =11.071, df= 5, p< 0.05) among health workers. But, this awareness of the risk factors did not significantly influence (13 =.084, t= 1.069, p> 0.05) the utilization of pap-smear testing among female health workers in Ibadan. It is surprising to note that the awareness of cervical cancer risk factors did not influence the utilization of pap- smear testing among health workers in Ibadan. In recommendation, female health workers should be sensitised and encouraged to subject themselves to pap-smear testing as the experience will serve as a source of empowerment in their pivotal role of adviser and developing consciousness, reliance and cooperation of other women. 2 results 2
- Cervical cancer screening 2 results 2
- Fall-risk-increasing drugs 2 results 2
- Falls 2 results 2
- HIV 2 results 2
- Health seeking behaviour 2 results 2
- Pap Smear test 2 results 2
- Practice 2 results 2
- Practices 2 results 2
- Pregnant Women 2 results 2
- Prevalence and Conservation Strategies 2 results 2
- Risk factors 2 results 2
- Satisfaction 2 results 2
- The study was carried out to investigate the prevalence and utilization of non-timber forest products (NTFPs) plant species in Omo and Shasha Forest Reserves, Southwestern Nigeria. Data were obtained through the use of structured questionnaires administered to households in forest communities. To complement information from the household survey, focus group discussions (FGDs) were also carried out in each of the sampled communities. In-depth interview (IDI) of forestry staff was further used to supplement the information collected. A simple random sampling technique was employed for the study. In Omo Forest Reserve (OFR), a total of seventy five species distributed in forty three families were recorded, while fifty six species in thirty one families were documented in Shasha Forest Reserve (SFR). Local end-uses of NTFPs include food and food supplements, snacks/sweeteners, wrapping leaves, soup and spices, beverages, dental care supplies, washing tools, roofing/construction materials, medicine and traditional rites items. While access to these resources is important to guarantee the socio-economic well being of the forest dwellers and communities, their sustainable management has not been taken seriously by policy makers thereby contributing to reduction of biodiversity and gradual but irretrievable loss of indigenous knowledge on the uses of most species. To ensure the sustainable utilization of NTFPs in these and similar tropical forest environments therefore, a number of conservation approaches are proposed. 2 results 2
- University of Ibadan 2 results 2
- Uptake 2 results 2
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