Functional characterization of candidate Persea americana nucleotide-binding leucine rich repeat (PaNLR) genes during Phytophthora cinnamomi infection

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The synthesis, characterization and preliminary biological evaluation of triazole complexes of palladium by Van Niekerk, Annick

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The production and purification of functional steroid hormone receptor ligand binding domains towards the development of a biological endocrine disruptor detection system by Tait, Timo

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The impact of HIV-1 subtype C Envelope N-glycosylation on DC-SIGN meditated modulation of DC function to facilitate transmission or enhance viral pathogenesis by Lumngwena, Evelyn Ngwa

“…Entry efficiency, DC-SIGN binding and trans-infection varied widely across all clones. …”
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Mechanisms of glucocorticoid pro-inflammatory effects on CCL20: crosstalk and synergy by Nhundu, Tawanda

“…The present study investigated whether the GC dexamethasone (dex) and the pro-inflammatory inducer TNFα could induce CCL20 expression in a variety of human epithelial cell lines, and a simian fibroblast cell line. Using Real-Time Quantitative Reverse Transcription PCR (qRT-PCR), it was confirmed that dex can induce CCL20 mRNA expression, and modulate the TNFα-induced expression in some, but not all cell lines. …”
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Regulation of transcription in Plasmodium falciparum, the causative agent of severe malaria: initial characterisation of PfTBP and PfTFIIA by Milton, Robert A

“…The severity of the disease is brought about by the variable expression of parasite proteins on the surface of infected red blood cells. The substantial morphological changes, together with the variable expression of cell surface proteins, are governed by tightly controlled stage-specific changes in gene expression patterns. …”
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Modulation of the progesterone receptor by progestogens, antiretroviral drugs and the glucocorticoid receptor by Enfield, Kim

“…However, since all cells that express the PR also express the GR in vivo to the best of the author's knowledge, characterising PR activity in the absence of detectable GR expression is unlikely to be physiologically relevant. …”
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Histone modifications and the Arabidopsis thaliana circadian clock by Motleleng, Liabo Lilian

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ASMT gene polymorphisms are associated with Autism Spectrum Disorder (ASD) symptom severity in a South African population by De Waal, Margaretha

“…Melatonin is a hormone in the circadian clock system, and is a biochemical signal for darkness to synchronise peripheral cells to the master oscillator. Clinical trials reported that melatonin supplementation at night assists in sleep initiation. …”
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Regulation of desiccation tolerance in Xerophyta seedlings and leaves by Lyall, Rafe

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Development of plant-produced African horse sickness vaccines by Dennis, Susan Jennifer

“…Such a vaccine would potentially provideprotection against all 9 serotypes of the virus and would have DIVA capability. …”
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Receptor concentration affects glucocorticoid action by Robertson, Steven Ernest

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Modulators of MRP1 promoter in Neuroblastoma cell lines by Ghabriel, Myret Said

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An experimental study of human melanoma cells cutured in vitro by Hoal, Eileen Garner

“…As has been found with all other melanomas studied, these cells released a plasminogen activator that was chemically and immunologically identical to tissue activator. …”
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Assessment of macrophage and granulocyte cell-enhanced phagocytosis of Mycobacterium tuberculosis

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Computational models for conformations of cell wall mycolates from Mycobacterium tuberculosis

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Cloning, sequencing and functional analysis of the chicken tyrosine gene promoter by Ferguson, Christine Anne

“…However, the level of expression from the various constructs differed markedly in the different cell types. In the tyrosinase-negative Hep G2 cells, low levels of expression were observed with all constructs. …”
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Characterization of a plasminogen activator from human melanoma cells cultured in vitro by Heussen, Christa, Heussen, Christa

“…These antibodies inhibited the activity of plasminogen activators released by all melanoma cells but had no effect on urokinase. …”
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Characterising the magnitude and breadth of T cell responses to SARS-CoV-2 vaccination by Chauke, Valencia Masego

“…There was no statistical difference in CD4 or CD8 responses against the pools between those who had received one or two initial doses. All seven spike pools were targeted by the CD4 and CD8 cells at both timepoints. …”
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