Anti-biofilm activity of the tick-derived antimicrobial peptide Os(11-22)NH2 against Candida albicans ATCC 90028

Get full text

Investigating the mechanism of action of hormones used in hormone replacement therapy via estrogen receptor subtypes and the influence of the progesterone receptor by Perkins, Meghan Samantha

Get full text

Immunochemical studies with tryptic peptides of tobacco mosaic virus protein by Milton, Raymond Cecil de Lisle

Get full text

Transcription regulatory networks in medulloblastoma. by Howeedy, Yasmeen Hesham

“…They account for 22% and 10% of all malignancies among children aged up to 14 years and 15-19 years respectively. …”
Get full text
Get full text

Development Of Recombinant Immunotherapeutics for Triple-Negative Breast Cancer (TNBC) by Ngwenya, Takunda

“…The rITs displayed a strong binding affinity for MDA-MB-468 TNBC cells. Cytotoxicity results revealed that both ETA and dETA-rITs can both target and kill MDAMB-468 TNBC cells. …”
Get full text

Functional characterisation of Hfq and identification of Hfq-dependent sRNAs in Pantoea ananatis

Get full text

Proteolytic and amylolytic enzymes for bacterial biofilm control

Get full text
Get full text

Investigation of particulate HIV-1 Env vaccine candidates using Zera® and SpyTag/SpyCatcher technologies by Ximba, Phindile Thobeka

“…SDS-PAGE, dynamic light scattering and negative stain electron microscopy indicated that gp140-ST was successfully bound to the VLPs, although not all potential binding sites were occupied. The immunogenicity of the coupled VLPs was evaluated in a pilot study in rabbits. …”
Get full text

Genome-wide analysis of carbohydrate active enzyme diversity and expression in Eucalyptus grandis

Get full text

Isolation and evaluation of the sugarcane UDP-glucose dehydrogenase gene and promoter by Van der Merwe, Jennie

Get full text

Improvement of foot-and-mouth disease virus vaccines and diagnostics through structural design

Get full text

Targeted depletion of RibF, a putative bifunctional FAD synthetase/ flavokinase in Mycobacterium smegmatis using CRISPR interference by Raphela, Mabule Lucas

“…Given the role of RF as a core component of the essential flavin cofactors, flavin mononucleotide (FMN) and flavin adenine dinucleotide (FAD), it was hypothesized that silencing ribF would disrupt the biosynthesis of all flavoproteins, crippling numerous (essential) processes within the organism. …”
Get full text

Generation of Glioblastoma specific SNAP based antibody fusion proteins for future radiolabelling application by Mayuni, Grace

“…The success of antibody-based targeted approaches lies in the selection of biomarkers that are selectively found in tumour cell populations. One type of biomarker is known as tumour-associated antigens (TAAs), which are antigenic substances present at a much relatively lower incidence on normal cells but highly correlated with certain tumour cells. …”
Get full text

In-silico guided design, synthesis and bio-evaluation of potential chemotherapeutic agents against malaria, cancer and disease-causing pathogens

Get full text

Systems biology of organellar carbon metabolism in Eucalyptus xylogenesis

Get full text

Improvement of the Capripoxvirus, lumpy skin disease virus for use as a vaccine vector by Munyanduki, Henry Munyaradzi

“…Similarly, full-length SOD induced cell death by necrosis to a greater extent than the SOD knock-out or nLSDV; and all viruses inhibited camptothecin induced necrosis. …”
Get full text

Genetic and phenotypic characterisation of selected african foot-and-mouth disease virus isolates

Get full text

Molecular modelling and crystallographic investigation of novel synthetic cathinone 2-methyl-4'-(methylthio)-2-morpholinopropiophenone (MMMP)

Get full text

Development of coupled enzyme assay and in vitro synthetic biology approach for glycosylation pathway characterization by Nashed, Abdullateef

“…Glycans play essential roles in living organisms that encompass a wide range of biological functions ranging from energy metabolism all the way through to intricate cell signalling pathways. …”
Get full text