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Characterization of the mitochondrial genomes of Diuraphis noxia biotypes
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Enhanced bioethanol fermentation from mixed xylose and glucose using free and immobilized cultures: mathematical model and experimental observation
Published 2019“…Predicted rates of Z. mobilis ZM4 were then validated with experimental data generated in this study. Then, the optimum initial biomass concentration required to provide a faster volumetric rate of sugar utilisation and ethanol production, as well as the optimum oxygenation level for xylose conversion using P. stipitis achieved through appropriate aeration were investigated through experimental observation and using a MATLAB mathematical model developed through combination of the Andrews and Levenspiel's models, with oxygen, substrate, cell and product terms. …”
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The Mycobacterium tuberculosis ESX-3 secretion system interactome
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Synthesis of novel staurosporine analogues as potential kinase inhibitors
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SQUID geomagnetic signal analysis and modelling of Schumann Resonances in the earth-ionosphere cavity
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Investigation of Neurexin 2 as a candidate for Parkinson's Disease
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A pharmacokinetic and antimalarial efficacy evaluation of pyridodibemequines and their metabolites
Published 2021“…The parents and major metabolites exhibited minimal toxicity against a mammalian cell line, and the metabolites are proposed to display reduced systemic toxicity, and human ether-a-go-go-related gene liability compared to the parent compounds. …”
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Micronisation of cowpeas : the effects on sensory quality, phenolic compounds and bioactive properties
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Expression and Purification of an efficacious recombinant Pulpy Kidney subunit vaccine made in N. Benthamiana
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Modulation of oxidative stress and inflammation using a grape seed derived polyphenol
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Functional characterisation of a SufT homologue in mycobacterium smegmatis
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Development of new antimalarial ferrocenyl-artesunate complexes
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The construction of gene silencing transformation vectors for the introduction of multiple-virus resistance in grapevines
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Development and optimisation of a zinc oxide nanowire nanogenerator
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The regenerative and anti-inflammatory capability of Prosopis Glandulosa
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Diversity and Ecology of Astroviruses in South African Bats
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Effects of adipose tissue extracellular matrix components on body fat distribution and insulin sensitivity in black and white South African women
Published 2019“…It is not clear whether high circulating insulin may directly increase HIF-1α expression and contribute to the formation of excess ECM, or whether increased insulin may simply be a concomitant downstream effect of increased insulin resistance, as a consequence of increased fibrosis and the generation of inflammation. By using a cell culture based study, the third study in this thesis (chapter 5), investigated the effects of increasing insulin concentrations on the expression of hypoxia and ECM related genes under normoxic and hypoxic conditions in mature 3T3-L1 adipocytes. …”
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