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Development of plant-produced Bluetongue virus vaccines
Published 2018“…Sheep vaccinated with insect cell-produced BTV VLPs were shown to be protected against challenge with wild type virus. …”
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Expression and characterization of plant produced AHSV nanoparticles encapsulating EGFP
Published 2024“…Alternatively, the structural proteins that form VLPs can have inherent amino acid motifs with a natural targeting affinity for receptors that may be overexpressed on the surface of certain types of cells, for example cancer cells. These properties impart VLPs with great potential as delivery vehicles of diagnostic and/or therapeutic molecules. …”
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Investigation of the effect of ocean acidification on the haemocyte proteome of the South African abalone, Haliotis midae
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Rhamnose metabolism and metronidazole resistance in B. thetaiotaomicron VPI-5482
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The functional analysis of XhLEA3-2 - a LEA_4 from the resurrection plant, Xerophyta humilis
Published 2018Get full text
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Investigation of particulate Bluetongue virus vaccines made in plants
Published 2023“…Although a number of different BTV VLPs have been produced in traditional protein expression systems, such as insect cells, these production methods are considered too expensive to compete with those of the commercial vaccines. …”
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Investigating the variation in susceptibility between Arabidopsis thaliana ecotypes in response to Botrytis cinerea infection
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Investigating the role of sufT in Mycobacterium abscessus using CRISPRi
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From proteomics to biotechnology. using the resurrection plant eragrostis nindensis to genetically engineer drought tolerant crops
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Events that shape genomes
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Functional Characterization of Plasmodium falciparum TATA-box binding-like Protein (PfTLP)
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Functional characterisation of ScIRT1 and ScIREG2 transport proteins in the nickel hyperaccumulator, Senecio coronatus
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Transcriptional regulation of seasonal desiccation tolerance in the fronds and rhizome of the fern Anemia caffrorum
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Chronotype in the South African population: the influence of longitudinal location
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Analysis of actinobacterial biodiversity in reservoir sediment and cave soil and screening of isolates for antimycobacterial activity
Published 2021“…The phylogenetic position of each identified strain within its genus was investigated by generating a phylogenetic tree based on its 16S-rRNA gene sequence. …”
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Autism Spectrum Disorder and Mitochondrial Dysfunction: The Role of Mitochondrial Dynamics
Published 2023“…Undifferentiated, neuronal-like SH-SY5Y cells were treated with NaP at 1.5mM, 3mM and 5mM to induce mitochondrial stress. …”
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Development of West Nile virus candidate vaccines in Nicotiana benthamiana
Published 2022“…Plants can produce and modify proteins in a similar manner to mammalian cells and production does not require sterile conditions or specialised facilities. …”
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The impact of HIV-1 subtype C Envelope N-glycosylation on DC-SIGN meditated modulation of DC function to facilitate transmission or enhance viral pathogenesis
Published 2018“…We generated pseudovirus of eighteen Env clones (PSVs) with variable number and position of potential N-glycan sites (PNGs) and compared their ability to infect TZM-bl cells, bind to Raji+ DC-SIGN cells, trans-infect TZM-bl cells when captured by either Raji-DC-SIGN cells or monocyte-derived dendritic cells (MDDCs) and modulate MDDC signaling by investigating the release of Interleukin-10 (IL-10) and other immune modulatory cytokines and MAPK activation. …”
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Novel expression and production of Foot-and-mouth disease virus vaccine candidates in Nicotiana benthamiana
Published 2018“…These VLPs are formed by the assembly of the FMDV capsid proteins VP0, VP1 and VP3, which are generated upon the proteolytic cleavage of the capsid precursor protein P1-2A, by the FMDV 3C-protease. …”
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Efficient radio resource management for future generation heterogeneous wireless networks
Published 2018“…The heterogeneous deployment of small cells (e.g., femtocells) in the coverage area of the traditional macrocells is a cost-efficient solution to provide network capacity, indoor coverage and green communications towards sustainable environments in the future fifth generation (5G) wireless networks. …”
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