Investigation into implementing a massively parallel sequencing workflow for forensic human identification in South Africa by Martin, Donna-Lee

“…An increase of 86% was observed in length- to sequence-based allele counts across several A-STR markers, with additional variation recorded in flanking regions. …”
Get full text

Investigation into implementing a massively parallel sequencing workflow for forensic human identification in South Africa by Martin, Donna-Lee

“…An increase of 86% was observed in length- to sequence-based allele counts across several A-STR markers, with additional variation recorded in flanking regions. …”
Get full text

Impact of Cytotoxic T Lymphocyte (CTL) escape mutations in acute/Early HIV-1 Subtype C Infection on Disease Progression by Chopera, Denis Rutendo

Get full text

Peripheral inflammatory and regulatory immune changes in HIV positive to HIV positive renal transplant recipients by Rautenbach, Stefan

“…Despite transplantation across Human Leukocyte Antigen (HLA) mismatches, there were few rejection events in the first year post-transplant (PT). Recipient CD4 counts did not decrease and HIV viral load also remained undetectable at one year PT. …”
Get full text

Assessing the effectiveness of the ART programme in the Western Cape Province of South Africa through triangulation of context-appropriate population level routine monitoring and s... by Osler, Margaret

“…Programmatic ART outcomes did improve during expansion of ART eligibility including into the time-period of the treat-all policy when CD4 count criteria were removed. More people accessed ART over time, independent of guideline changes, improving population HIV outcomes. …”
Get full text

Automated pre-processing of fluorescence microscopy data for the analysis of mitophagy. by Batt, Richard

Get full text

Isolation and characterisation of novel DNA aptamers against Mycobacterium tuberculosis biomarkers: new tools for tuberculosis diagnostics by Amos-Brown, Bianca

“…In order to overcome tuberculosis in developing countries innovation in diagnostics is key to administering treatment. …”
Get full text

Burkitt and Burkitt-like lymphoma/leukaemia at Groote Schuur Hospital from 2005 to 2014: a retrospective review by Koller, Anna J

“…Results: Burkitt lymphoma (BL) (n=109) was more frequent than Burkitt-like lymphoma (BLL) (n=41) and at presentation there were no significant differences in HIV prevalence (86% vs 78%); median CD4 count (213 vs 207 cells/μL); bone marrow involvement (49% vs 34%), leukaemic dissemination (37% vs 27%) and most frequent site of diagnosis (abdomen/pelvis; 26% vs 29%), respectively. …”
Get full text

Structural brain connectivity of HIV-positive children: a graph network analysis study by Fouche,Jean-Paul

“…Cortical thickness, surface area and gyrification were positively associated with CD4 count as a marker of disease severity. In conclusion, this project demonstrated abnormal brain structure and structural connectivity of brain structure in regions involved with motor development, executive function, and language fluency and generation in treated children living with HIV. …”
Get full text

A review of the implementation of the prevention of mother-to-child transmission program in the George sub-district, Western Cape by Schaefer, Rachel

“…Introduction The most common cause for HIV infection in children in developing countries is the vertical transmission of HIV from mother to child. …”
Get full text

Die ekologie en taksonomie van die mondlaktobasille van kinders

Get full text

Human Immunodeficiency Virus/Human Papillomavirus co-infection and host molecular genetics of cervical carcinoma by Chambuso, Ramadhani Salum

“…A subgroup of women who are co-infected with human immunodeficiency virus type 1 (HIV1) and human papillomavirus (HPV) progress relatively rapidly to cervical disease regardless of the number of absolute CD4 count. During infection, viral peptides are recognized by the host immune system. …”
Get full text

Growth and mortality rates of sardine (Sardinops sagax) pre-recruits in the Southern Benguela region during early 2001 by Weni, Elliot

Get full text

Potential contributors to hospital admissions among HIV-positive patients in South Africa in the Era of Haart

Get full text
Get full text

Optimizing Tuberculosis Diagnosis in HIV-Infected Inpatients Meeting the Criteria of Seriously Ill in the WHO Algorithm by Griesel, Rulan

“…Results We enrolled 484 participants: median age 36 years, 65·5% female, median CD4 count 89 cells/μL, and 35·3% on antiretroviral therapy. …”
Get full text

Measurement of physical activity for public health purposes : validity and reliability of the International Physical Activity Questionaire(IPAQ) by Bohlmann, Isabelle Marie Therese

“…Criterion validity for CSA counts and total physical activity in the long IPAQ was r = 0.50 (P < 0.001), for CSA counts and total vigorous activity r = 0.35 (P < 0.01), and for CSA counts and total job activity r = 0.51 (P < 0.001). …”
Get full text

Stochastic analysis of AIDS epidemiology

Get full text
Get full text

Characterisation and identification of the active microbial consortium present in Kepi grains by Schoeman, Tersia

Get full text

Diagnostics for joint models for longitudinal and survival data by Singini, Isaac Luwinga

“…In this setting we considered two longitudinal outcomes, square root CD4 cell count which was Gaussian in nature and antiretroviral therapy (ART) uptake which was binary. …”
Get full text