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Characterising the anticancer effects of a small molecule with potential to inhibit nuclear import via karyopherin beta1
Published 2018“…Since all these cell regulatory functions are critical for normal cell function, dysregulation of Karyopherin proteins may have an impact on cancer cell survival. …”
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Effect of maternal separation on stress-related proteins measured in a 6-hydroxydopamine rat model of Parkinson’s disease
Published 2014Get full text
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Some of the mechanisms for coexistence of tree species diversity in tropical forests: a review of effects of tree density dependence
Published 2023-01ArticleFull Text AvailableAccess Repository -
Efficacy and physiological effects of novel drug combinations used to immobilise free-living African lions (Panthera leo)
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Understanding the Flood Early Warning System for Flash Floods and its Effectiveness: The City of Windhoek Municipality Case Study
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The effect of inhibiting KPNB1-mediated nuclear import on cancer cell biology and inflammatory transcription factor signalling
Published 2018“…The aim of this study was to investigate the anticancer and anti-inflammatory effects of inhibiting nuclear import via KPNB1 and to characterise the in vivo effect of the small molecule inhibitor of nuclear import, INI-43, on tumour formation. …”
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Investigating the effect of a small molecule, Inhibitor of Nuclear Import (INI-43) as a pan-cancer treatment
Published 2024“…Our study found that treatment with INI-43 has a stabilising effect on KPNβ1, suggesting that INI-43 physically binds to KPNβ1. …”
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