Profiling Genome-Wide DNA Methylation Patterns in Human Aortic and Mitral Valves by Halawa, Sarah

“…Cardiac valve structure and function are complex and include dynamic interactions between cells, extracellular matrix (ECM) and their hemodynamic environment. Valvular gene expression is tightly regulated by a variety of mechanisms including epigenetic factors such as histone modifications, RNA-based mechanisms and DNA methylation. …”
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Honeybush extract as a viable intervention against oxidative stress and mitochondrial dysfunction in a glucotoxic in vitro model by Le Roux, Kyle

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Investigating the effect of Staphylococcus epidermidis on the growth dynamics of Staphylococcus aureus in atopic dermatitis by Moonsamy, Rasalika

“…The majority (70%) of established biofilms were composed of a proteinaceous matrix. Expression of esp was detected in 63% of S. epidermidis isolates. …”
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Exploring the potential for biomarkers to aid forensic diagnosis of traumatic brain injury (TBI) – a systematic literature review and meta-analysis by Velcich, Carly

“…Understanding its pathophysiology is imperative for clinical diagnosis, treatment, and cause of death determination. …”
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Investigating the effect of Staphylococcus epidermidis on the growth dynamics of Staphylococcus aureus in atopic dermatitis by Moonsamy, Rasalika Tamika

“…The majority (70%) of established biofilms were composed of a proteinaceous matrix. Expression of esp was detected in 63% of S. epidermidis isolates. …”
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Leveraging big data resources and data integration in biology: applying computational systems analyses and machine learning to gain insights into the biology of cancers by Sinkala, Musalula

“…Recently, many "molecular profiling" projects have yielded vast amounts of genetic, epigenetic, transcription, protein expression, metabolic and drug response data for cancerous tumours, healthy tissues, and cell lines. …”
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Investigation of the potential of Spleen Tyrosine Kinase (SYK) as a target for host-directed therapy during mycobacterial infection in macrophages by Mohapi, Sephekana Samuel

“…Spleen tyrosine kinase (SYK) plays an important role in innate immune signalling. It is expressed on innate immune cells such as macrophages. …”
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The tetrapeptide Ac-SDKP and angiotensin converting enzyme in tuberculous pericarditis and fibrosis by Ramasamy, Vinasha

“…This suggests that an increase in ACE activity in the pericardium following infection by the mycobacterium leads to a reduction of the levels of the antifibrotic peptide which is likely to contribute to the pathophysiology of fibrosing pericarditis. A mass spectrometric (MS) approach was employed in order to identify proteins whose expression is modulated by the effect of Ac-SDKP in the proteome and secretome of a human lung fibroblast cell line (WI-38). …”
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Profiling circulating microRNAs in pregnancies complicated by type 1 diabetes, type 2 diabetes and gestational diabetes mellitus

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Exploring the interactions of hyperglycaemia, SARS-CoV-2 spike protein & iron in HepG2 cells by Breytenbach, Jacomi Heidi

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Investigation of differentially methylated microRNA genes in Type 2 diabetes by Alley, Philbe-Jeanne

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Investigating aberrant DNA methylation patterns in LOXL2 as a potential predictor of diabetes-induced cardiac dysfunction by Erasmus, Melisse

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Longitudinal transcriptomic profiling of whole blood during tuberculosis treatment by Odia, Trust Osee

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Characterisation of cardiac protein changes post death: pilot study by Mokaila, Dipolelo

“…Scientific evidence has revealed that the expression, concentration, and stability of proteins do not remain the same after death. …”
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Investigating the onset of insulin resistance and non-alcoholic fatty liver disease in obesity-induced cardiac dysfunction by Boshoff, Anel W.

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2020-12-11 Global transcriptomic investigation of the human macrophage response towards pathogenic/non-pathogenic mycobacteria by Mishra, Abhilasha Madhvi

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Identification of novel DNA methylation signatures in the development of cardiovascular disease by Jooste, Tracey

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Investigating the integrity of the vasculature and structural relationships of pericytes, astrocytes and the endothelial glycocalyx in an ex vivo hyperglycaemic rat retinal model by Musa, Glory Chinuru

“…Heat shock proteins showed higher expression in hyperglycaemic rat retina compared to the normoglycaemic group. …”
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The maladaptive effects of HIV protease inhibitors (Lopinavir/Ritonavir) on the rat heart by Reyskens, Kathleen Maria Simone Elise

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Efficacy and mechanism of action of intrahippocampalD-cycloserine in an animal model of Posttraumatic Stress Disorder (PTSD) by Fairbairn, Lorren Rosli

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