Investigating the ameliorative potential of Aspalathus linearis and Cyclopia intermedia against lipid accumulation, lipolysis, oxidative stress and inflammation by Mamushi, Mokadi Peggy

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Investigating the pathways involved in the progression of fibrosis in tuberculous pericarditis by Fikamva, Siyavuya

“…Thirteen autoantibodies were expressed in the TBP pericardial fluid samples. The levels of leucine-rich repeat flightless-interacting protein 2 (LRRFIP2) were increased in TBP samples compared to in control samples. …”
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Circulating microRNAs in neuromuscular disorders by Mousa, Nahla

“…In addition to DNA variations and proteins, circulating microRNAs are also used as surrogate markers in different disease conditions like cardiovascular diseases and cancer. microRNAs are endogenous epigenetic regulators of gene expression. Many studies reported the modulation in microRNAs expression in various body fluids at different pathophysiological conditions and hence they can be used as promising non-invasive diagnostic and prognostic biomarkers and most importantly they can be used as monitoring screen to detect the successfulness of therapeutic interventions since their expression status is dynamic and can change based on the physiological conditions and the behavior of the cells and the responsiveness to external stimuli. …”
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Characterisation of high fat, high sugar diet-induced epigenetic changes in skeletal muscle of wistar rats and metabolic effects of an aspalathin-rich rooibos extract by Myataza, Asive

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Molecular regulation of the cardiac-enriched acetyl-CoA carboxylase isoform (ACCβ) : a novel target for therapeutic interventions in cardiovascular disease by Makaula, Siyanda S S

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Investigating the immune modulatory properties of kisspeptin: implications for pregnancy by Botha, Stefan Marc

“…The hypothesis of this study is that kisspeptin alters the expression of anti-and pro-inflammatory cytokines and may thus influence the establishment of immune tolerance in pregnancy. …”
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Risk factors associated with blood pressure variation in sickle cell disease in Cameroon by Nguweneza, Arthemon

“…Additionally, tissue expression analysis did not reach significant thresholds. …”
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Autophagic Reprogramming of Macrophages Polarization by Mazher, Mayada Mahmoud Zaki Mohamed

“…Interestingly, autophagy is implicated in disease pathophysiologies such as Crohn’s disease, cancer, and neurodegenerative diseases. …”
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A proteomic analysis of the ventral and dorsal hippocampal brain areas of serotonin knockout rats by Fairbairn, Lorren R.

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Modelling non-communicable diseases in autism spectrum disorder: a pharmacological approach by Coetzee, Johanna Adriana

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Autophagic Reprogramming of Bone Marrow-Derived Macrophages by Mazher, Mayada Mahmoud Zaki Mohamed

“…Interestingly, autophagy is implicated in disease pathophysiologies such as Crohn’s disease, cancer, and neurodegenerative diseases. …”
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Evaluating the neuroprotective effect of curcumin on a PINK1 cell model of Parkinson's disease by Chetty, Devina

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Microbiological, genomic and transcriptomic analyses of human tuberculosis lung cavities by Lenders, Laura Mary

“…In peri-cavitary normal-appearing tissue only 33% of pathways showed significant expression change, despite having a similar bacillary burden to diseased tissue. …”
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The platelet laminin receptor : discovery of a 67kDA receptor for laminin on the membranes of human platelets : characterisation and isolation by Holland, Errol Anthony

“…The possible relevance of this receptor in the pathophysiology of the metastatic process is discussed.…”
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Angiogenic, apoptotic and autophagic profiling of chronic myeloid leukaemia patients’ platelets ex vivo before and after treatment with Imatinib

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An investigation into the P13-K/AKT signalling pathway in TNF-a-induced muscle proeolysis in L6 myotubes by Sishi, Balindiwe J. N.

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The search for the PFHBI gene : refining the target area and identification and analysis of candidate gene transcripts by Arieff, Zainunisha

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The role of ketone bodies in autophagic flux, cellular energetics and injury-induced neurotoxicity by Wurz, Jana

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The Possible Ameliorating effects of Rooibos, Honeybush and Sutherlandia on diabetes-induced reproductive impairment in adult male Wistar rats by Omolaoye, Temidayo Siyanbola

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The responses of endothelium to insult : does endothelial heterogeneity play a role in in vitro cell models by Mthethwa, Mashudu

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