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Modulating ADAM-10 activity and expression in cervical and oesophageal cancer cells
Published 2017“…An increase in epithelial cell markers (E-Cadherin, B-Catenin) and a decrease in mesenchymal marker expression (Vimentin) post treatment with the compounds tested strongly suggested that ADAM10 plays a role in mesenchymal cell transition. …”
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Human host and malaria parasite genome variations to susceptibility to malaria
Published 2024“…This may also have relevance for future consideration of pharmacogenetic testing for a person traveling to malaria endemic areas from non-endemic areas, such as South Africa. …”
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Click chemistry for the preparation of advanced macromolecular architectures
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Porous metal-organic frameworks for sorption of volatile organic compounds
Published 2021“…Using 34pba as a single ligand and Cu2+ as the metal ion led to the formation of a 2D [(Cu(34pba)2]·DMF) (4) while a little variation of solvent mixture resulted in a 3D {[CuCl2(34pba)2]∙solvent}n (7) structures. The functionalized ligands 44paba and 34paba (34paba = 3-(pyridyn-4-ylmethyl)aminobenzoate, 44paba = 4-(pyridyn-4- ylmethyl)aminobenzoate) were used with Cu2+ centre to prepare [Cu(44paba)·(H2O)·(DMF)]n (5) and {[Cu3(34paba)5(H2O)2]·(DMF)2}n (6), both of which are 1D structures. …”
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Move-Biased Monte Carlo Simulation Method for Protein Native Structure Prediction
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Investigating the gut and blood microbiome in Parkinson’s disease, schizophrenia, and posttraumatic stress disorder
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Properties and potential use of Irvingia gabonensis and Irvingia wombolu kernel extract as an eco-friendly wood adhesive
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A Web-Based Change Control Management Toolkit for Lump-Sum Turnkey Contractors: Transformation to Third Generation
Published 2021“…The verification and validation results have demonstrated that the WCCMT’s functionalities and capabilities are satisfactory and acquired a “very good” rating by the construction practitioners with an overall mean score of 4.3 out of 5. …”
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Conception of a flexible workpiece carrier to enable automated activities during transportation using a mobile manipulator
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The profile of a surgical ICU in a public sector tertiary hospital in South Africa
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Oxidative dehydrogenation of ethane with carbon dioxide over iron-nickel nano-alloys supported on metal oxide overlayers
Published 2023“…Promoters such as Fe-based oxides have been studied to enhance the CO2-activation functionality and stability of the oxides [5]. A Density Functional Theory (DFT) study suggested that bimetallic alloys can have superior activity for CO2-activation compared to their monometallic counterparts [16]. …”
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Synthesis of novel Tetrahydroisoquinoline-related estrogen receptor modulators
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The development of group VIII trinuclear transition metal complexes as chemotherapeutic and photodynamic therapy agents
Published 2025“…A series of trimetallic 2-ferrocenylbenzimidazole complexes, along with their respective mononuclear congeners, were prepared. The 5-position of the benzimidazole scaffold was substituted with varying hydrophobic electron-withdrawing or -donating functionalities, to offer insight into the effect of these substituents on the overall biological activity. …”
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Identifying potentially valuable flavour fractions from South African botanical extracts using LC Taste as a rapid screening method
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Bifacial photovoltaic module performance evaluation with reference to the solar spectrum and broadband irradiance
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