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A computational framework for parallelised protein folding simulation and the investigation of protein stability
Published 2025Get full text
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A decision support framework towards a simulation model for the risk-constrained vehicle routing problem
Published 2019Get full text
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Economic capital allocation to market and survival risk for pure endowment products
Published 2023Get full text
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Quantification of production risk in the underground mine planning process
Published 2014Get full text
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Credit default swaps in a roll-over risk framework
Published 2022“…This price is then compared to that obtained from a traditional Monte Carlo simulation approach. The former is shown to produce accurate results with greater computational efficiency, providing a useful way to price complex financial instruments when the state variables are defined in an appropriate form.…”
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The Development of a Reduced Order Model for Prediction of Haemodynamic and Biochemical Changes in a Computational Cerebral Aneurysm Thrombosis Model
Published 2024“…However, medical imaging is not always possible, thus there is a need for the development of computational tools to assist with predictions. A computational fluid dynamics (CFD) model that couples haemodynamics and biochemistry was developed to simulate cerebral aneurysm thrombosis. …”
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Modelling of tuberculosis transmission risk for a research Facility in eMalahleni, South Africa
Published 2021Get full text
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Combating Data Leakage in the Cloud
Published 2020Get full text
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Efficient rendering of real-world environments in a virtual reality application, using segmented multi-resolution meshes
Published 2020Get full text
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State estimation for non-linear transmission models of Tuberculosis
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Modifying copulas for improved dependence modelling
Published 2021Get full text
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In situ bioremediation of hexavalent chromium by permeable reactive barrier using wastewater sludge bacteria
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Forecasting spare parts demand using condition monitoring information
Published 2018Get full text
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Development Of Recombinant Immunotherapeutics for Triple-Negative Breast Cancer (TNBC)
Published 2024“…This study aimed at developing single chain fragments of variability (scFvs) derived from publicly available sequences of antibodies that target three CSRs overexpressed in TNBC, genetically fused to wild-type ETA (wt ETA) or a mutant version of ETA that was generated using advanced computer simulation by our collaborating partner, Professor Paolo Carloni from Forschungszentrum Jülich, Germany. …”
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