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The use of m-Health active participant centred (MAPC) systems to improve surveillance of adverse events following Immunization (AEFIs) in Zimbabwe
Published 2025“…Introduction A robust national AEFI surveillance system ensures timely AEFI detection, good quality AEFI reports, prompt case investigation and robust causality assessment for corrective AEFI case management, signal detection and appropriate feedback ultimately to improve public safety and trust in vaccines and the immunization programme. Each AEFI surveillance method has advantages and disadvantages. …”
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Cervical neoplasia in women with and without HIV-related immune depletion : epidemiology and pathogenesis related to HPV types
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Correlates of tuberculosis and non-tuberculosis morbidity and immunity in sub-Saharan African HIV-exposed, uninfected infants
Published 2025“…BCG vaccination also enhances heterologous protective immunity against infections through epigenetic reprogramming of innate immune cells (known as “trained innate immunity”). …”
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Complex interventions in complex health systems: Hepatitis B birth-dose vaccination programs in the African region
Published 2024“…We further demonstrate how these complex interactions contribute to the sub-optimal performance of hepatitis B birth-dose vaccination programs in the African region. By identifying sources of complexity at the intersection of hepatitis B birth-dose vaccination programs and health systems in Africa, we can better inform the design of immunization programs responsive to the contexts they are embedded in. …”
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Differences in the innate immune environment of human breast milk of HIV-infected and -uninfected mothers in Tshwane, South Africa
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The effects of in utero HIV and ART exposure on infant T-cell and monocyte activation, function and regulation of immune-modulatory pathways
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Effectiveness of pneumococcal vaccine in preventing hospital admissions for pneumonia among the elderly
Published 2020Subjects: “…Immunization Programs…”
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A Multimodal Immune System Inspired Defense Architecture for Detecting and Deterring Digital Pathogens in Container Hosted Web Services
Published 2023“…With the increased use of web technologies, microservices, and Application Programming Interface (API) for integration between systems, and with the development of containerization of services on operating system level as a method of isolating system execution and for easing the deployment and scaling of systems, there is a growing need as well as opportunities for providing platforms that improve the security of such services. …”
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Programmed cell death-ligand 1 (PD-L1) expression in HIV-associated diffuse large B-cell lymphoma – role and regulation
Published 2025“…The complex biology that underpins HIV-associated DLBCL remains largely undefined, necessitating clinical and molecular investigations to identify biomarkers which can be targeted for therapy, specifically within those populations most affected, such as in Sub-Saharan Africa. The programmed death-1/programmed death-ligand 1 (PD-1/PD-L1) signalling pathway is an important immunoregulatory mechanism that dampens the immune response by inhibiting T cell activity, playing a central role in controlling and maintaining tolerance to self-antigens. …”
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Establishing an in-house real-time polymerase chain reaction assay to quantify T-cell receptor excision circles and kappa-deleting recombination excision circles for use in screeni...
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Characterisation of Deladenus siricidicola genes potentially involved in parasitism and host immunomodulation
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Reasons for default follow - up of antiretroviral treatment at Thekganang ARV clinic
Published 2015Get full text
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