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Impact of the parasitic helminth Schistosoma mansoni on host anti-viral vaccine responses: proof of concept from the anti-polio vaccine
Published 2022“…The disease remains greatly neglected by global health control programmes thus classified as a top neglected tropical disease of humankind. …”
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Uncovering Potential Therapeutic Targets for Spinal Cord Injury; Insights from Single-Cell and Cross-Species Transcriptomics
Published 2026“…These analyses revealed shared enrichment of cell-cycle processes, immune system response, and extracellular matrix (ECM) remodelling. …”
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Investigating the structure-function relationships of Plasmodium Haem Detoxification Protein and Phosphatidylinositol 4-kinase
Published 2023“…The second aim of this project was to use Plasmodium vivax PI4Kβ inhibition assays coupled with site-directed mutagenesis and mass spectrometry to support target-based malaria drug discovery programs focused on the development of both ATP-competitive and covalent Plasmodium PI4Kβ inhibitors. …”
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Differential effects of combinations of anti-retrovirals and progestins on gene expression and HIV-1 replication in cells of the female genital tract
Published 2018“…With the development of programmes using anti-retrovirals (ARVs) to prevent HIV infection, the concurrent use of hormonal contraception and ARVs is likely to increase in young women. …”
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Investigation of Tuberculosis in Domestic Goats (Capra aegagrus hircus) in KwaZulu-Natal
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Host genetic factors in susceptibility to mycobacterial disease in the African buffalo, Syncerus caffer
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Standard echocardiography versus handheld echocardiography for the detection of subclinical rheumatic heart disease: A systematic review
Published 2019“…Rheumatic heart disease (RHD) is a permanent heart valve condition resulting from an abnormal immune reaction to group A streptococcal (GAS) infection typically occurring in childhood. …”
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Mycolic acid as antigen or analyte in tuberculosis
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Redress for victims of cartel activity
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The impact of maternal HIV infection on uninfected neonate brain structure
Published 2022“…Successful prevention of mother-to-child HIV transmission (PMTCT) programs have reduced the risk of infant HIV infection in South Africa from 8% in 2008 to an estimated 1.4% in 2015, resulting in an increasing population of HIV-exposed uninfected (HEU) children. …”
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Development of new recombinant vaccines for rabies and dog population management
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A biscuit fortified with iron, iodine and B-carotene as a strategy to address micronutrient deficiencies in primary school children
Published 2023“…Long-term evaluation of this programme, however, showed that improved micronutrient status is not sustained during the long summer school holidays, and it is suggested that the biscuit programme is supplemented with other strategies, such as local food production programmes and nutrition education. …”
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Analysis of schizophrenia susceptibility variants identified by GWAS : a bioinformatics and molecular genetics approach
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Urban agriculture : food for thought
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Factors contributing to the failure by parents and care givers to disclose the status of children who are HIV positive
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Insights of urban and rural female youth regarding the nature and consequences of sexual risk behaviour
Published 2017Get full text
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