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Whole-exome sequencing of cases with familial cardiomyopathy
Published 2021“…As heterogeneous disorders, over 50 genes have been implicated in these cardiomyopathies to date. However, the yield of genetic testing ranges from less than 40% in idiopathic DCM to over 50% in ACM and HCM, indicating that many causal genes are yet to be identified. …”
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Investigation of molecular regulatory control of the cardiac-enrich acetyl-CoA carboxlase
Published 2024“…Collective data gathered from studies of different forms of heart disease indicate a common denominator among them, namely a detrimental change in energy homeostasis. …”
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Analysis of driver gene mutations in oesophageal squamous cell carcinoma
Published 2026“…The asymptomatic development of OSCC, results in late diagnosis of the disease with a poor prognosis, typically ranging from 5-10% at 5-year post-diagnosis in Africa. This study investigated the genomic landscape of OSCC in the South African population by whole-genome sequencing (WGS) and whole-exome sequencing (WES). …”
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Genetic aetiology of anxiety disorders
Published 2016Get full text
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A model for a comprehensive electronic school dictionary for South African primary school learners
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Characterization of the interaction between acetylcholinesterase and laminin : a template for discovering redundancy
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The determination of nutrient requirements and development of artificial diets for the mass rearing of insects of economic importance
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Colouring the grey areas of insect mass-production to solidify their use as feed, food and biological control agents
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The role of the intestinal immune system in the development and treatment of type 2 diabetes
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Mathematical modelling of bacterial attachment to surfaces : biofilm initiation
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Determination of the mechanism of synergy of SQ109 with rifampicin and isoniazid in Mycobacterium smegmatis
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Improving the protein secretion capacity of Saccharomyces cerevisiae with strain engineering
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The effects of native Saccharomyces cerevisiae snare gene over expression on Heterologous cellulase secretion
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Employing omics to investigate the macrophage response to infection with pathogenic and non-pathogenic mycobacteria
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Regulation of efflux in rifampicin resistant mutants of Mycobacterium tuberculosis
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Identification and characterisation of specific allergens of Abalone (haliotis midae; mollusca) and other seafood species
Published 2018“…In view of the limited information available from published studies, especially on mollusc allergens, more detailed characterisation of the major allergens from different shellfish and fish is necessary to accurately predict cross-allergenicity. …”
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Inhibition of biofilm formation of foodborne pathogens by selected South African medicinal plants
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Modulation of oxidative stress and inflammation using a grape seed derived polyphenol
Published 2016Get full text
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