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Immunoelectron microscopic characterization of glial intermediate filaments in human gliomas by Geiger, Dietrich Horst
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Early-stage design and development of mine waste valorisation technologies with expert input: a case study of South African sulfide-enriched coal waste by Stander, Helene-Marie
Published 2024“…Distinguishability improved with a more careful selection of “high-quality” experts and again when interviews were conducted with these experts, but not to the point of enabling defensible decision support. …”
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- In Nigeria, as in many developing countries, the private health sector provides a significant proportion of reproductive health services. However, there are concerns about the quality of the reproductive health services provided by personnel operating in this sector. Few interventions exist to improve the quality of reproductive health services being provided by private practitioners. This three year intervention project, which was implemented in Oyo, Ogun and Gombe States, was designed to improve the capacity of personnel working in the private sector to deliver quality reproductive health service to their clients. One hundred and thirty nine privately owned health facilities participated in the project. Baseline data were collected from staff and clients using these facilities through self-completed questionnaires. A total of 458 nurses/auxiliaries were trained to improve their counseling and service delivery skills; 138 proprietors/proprietresses were trained on total quality management to enhance the quality of reproductive health service; and 84 physicians' knowledge were updated on reproductive health/family planning, and post-abortion care. Provision of contraceptive, drugs for treatment of sexually transmitted infections, supply of equipment and development of educational materials were the other components of the intervention. A follow-up survey was conducted three years after implementing the interventions to gauge outcome. At baseline, only 35.2% managed postpartum sepsis compared to 97.8% at follow-up. Thirty-nine percent provided post-abortion care at baseline the figure rose to 97.2% at follow-up. The proportion of respondents who reportedly provided family planning services increased from 39.5% at baseline to 43.0% at follow-up. Report of managernent of persons living with HIV/AIDS increased from 16.0% to 24.3% while counseling services increased from 36.1 % to 37.6%. At baseline, only 55% of the health workers reported that they had male condoms in stock, the figure rose to 88.2% at follow-up. Sixty-one percent of clients reported that it took 1- 5 minutes before being attended at follow-up, compared to 95% who claimed they spent about an hour before receiving care at baseline. The interventions improved availability and quality of reproductive health services provided by private health facilities. Similar interventions should be replicated to scale up the proportion of private health facilities that provide quality reproductive health services in the country. 2 results 2
- Mental health care 2 results 2
- Pregnant Women 2 results 2
- Sickle Cell Disease 2 results 2
- 30‑day Mortality Rate 1 results 1
- Acute Care 1 results 1
- Adolescent Mothers 1 results 1
- Anglophone 1 results 1
- Ante-Natal 1 results 1
- Antenatal Care 1 results 1
- Antibody avidity 1 results 1
- Asthma is one of the most prevalent non-communicable respiratory diseases in less developed countries. Nigeria ranks 49th in asthma prevalence among children worldwide. Previous studies have focused on asthma triggers and the seasonal pattern of asthma in children, yet they have not examined the influence of household attributes and activities on asthma prevention and management among children. This study was, therefore, designed to examine the perceived factors responsible for asthma in children, perceived household attributes and activities influencing its prevention and management, the influence of intergenerational factors and the pathways for seeking care for children living with asthma in Ibadan.The Health Belief Model served as the framework, while cross-sectional survey design was employed. The University College Hospital (Tertiary Hospital), Adeoyo Maternity Hospital (State Hospital), while Our Lady of Apostles Catholic Hospital (Private Hospital) were purposively selected. A sample of 273 respondents was drawn using Cochran (1977) formula. Purposive sampling was used to administer a structured questionnaire to parents of children aged 6 to 14 years, and physician-diagnosed asthma patients attending asthma clinics comprising UCH (124), Adeoyo Maternity Hospital (84) and Our Lady of Apostles Catholic Hospital (65). In-depth interviews were conducted with 10 children living with asthma in each of the hospitals, while Key Informant Interviews were also conducted with health practitioners in each of the hospitals. Six case studies were conducted with grandparents of children living with asthma to probe the influence of intergenerational factors. The Quantitative data were analysed using descriptive and inferential (chi-square and logistic regression) statistics at p≤0.05, while the qualitative data were content analysed.The Respondents’ age was 37±5.7years, 87.2% were female, while 63.8% had tertiary education. A majority (67.0%) lived in rented houses, while 69.6% used upholstered furniture and 73.6% used asbestos as roofing material. Nearly half (45.9%) perceived asthma to be caused by environmental factors (dust, smoke and weather conditions), inherited factors (37.5%), spiritual attack (13.0%), and punishment for sin (3.5%). Cooking methods (90.1%), cooking fuel (79.1%) and poor ventilation (72.9%) were reported as household attributes triggering asthma in children. Activities such as frying (χ2=6.00), baking (χ2=6.30) and laundry (χ2=7.14) were significantly associated with regularity of asthma attacks. The respondents’ religion (χ2=10.26), income (χ2=29.58), family type (χ2=15.18), ownership of house (χ2=8.77), type of house (χ2=23.88), education (χ2=52.07), household size (χ2=18.14), age of children living with asthma (χ2=6.14), occupation (χ2=18.60) and household decision making (χ2=4.20) were significantly related to treatment pathways. Family history of asthma was vital in its management in children. Grandparents’ experiences of use of natural home remedies such as honey, pawpaw leaves, camphor, mango seeds and turmeric were reported in the management of children with asthma. Household attributes and activities of children living with asthma in Ibadan influenced the prevention of asthma and was moderated by socio economic status, while natural home remedies were used in the management of asthma. Households with children living with asthma should improve housing conditions and cooking technologies. 1 results 1
- Asthmapreventionandmanagement. 1 results 1
- Awareness 1 results 1
- BACKGROUND: Early mobilisation of acute stroke survivors has been associated with fewer deaths and better clinical outcomes. Yet, there are conflicting reports about the knowledge, attitude and practice of early mobilisation among clinicians. We investigated the knowledge, attitude and practice of early mobilization among health care professionals in South-West, Nigeria. MATERIALS AND METHODS: All the 159 health care professionals comprised 68(42.8%) nurses, 45(28.3%) physicians and 46(28.9%) physiotherapists involved in acute stroke care were surveyed using a content-validated questionnaire. Pearson’s Product Moment correlation and ANOVA were used to analyse data at p < 0.05. RESULTS: Most (n=147; 92.5%) of the participants agreed that early mobilization reduces complications of immobility. Majority of the HCPs were knowledgeable and had positive attitude towards early mobilisation (n=139; 87.4%). Attitude differed significantly across different healthcare professions (p=0.02). Most health care professionals (n=149; 93.7%) reported practicing early mobilization of acute stroke patients. There was a significant relationship between years of work experience and each of knowledge and attitude (p<0.05) CONCLUSIONS: Although, many health care professionals expressed concerns about the risks of early mobilization, including possibility of death, they reported practicing early mobilisation. It may be necessary to conduct a risk-benefit analysis of early mobilisation and provide appropriate practice guidelines to promote implementation. This could further enhance the health care professionals’ confidence in practicing early mobilisation and improve stroke care. 1 results 1
- Background. A key to the effective management of malaria is prompt and accurate diagnosis, and the use of malaria rapid diagnostic tests (mRDTs) is becoming relevant in the absence of reliable microscopy. This study explored the phenomenon of using the wrong buffer vial (often a kit from another brand or buffer from HIV rapid test kits), dextrose, saline or distilled water among health care providers who used RDTs for malaria diagnosis in resource poor settings in Enugu South East, Nigeria. Materials and Methods. Laboratory personnel (medical laboratory scientists, technicians, assistants, nurses, community health extension workers (CHEW), community health officers (CHO) and doctors) were interviewed using structured questionnaires and results were checked using the SOP checklist. The selection criterion was a prior experience with using RDTs, and any facility that did not use RDTs was excluded. Results. Of the 80 study participants that completed their questionnaires, 56.3% reported that malaria diagnosis was positive using non-buffer RDTs detection while others reported negative results. Among the various professionals who used RDTs, 76.2% reported to have run out of RDT buffer stock at least once. Of the study participants that ran out of RDT buffer solution, 73% declared to have used non-RDT alternatives (physiological saline, 0.9% NaCl), distilled water, HIV buffer or ordinary water). Only 30% had received formal training on the proper usage and application of RDTs while 70% had never received any formal training on RDTs but learnt the technique of using RDT on the job. Conclusions. This study demonstrated that at least three quarters of health care workers in a resource poor setting had run out of buffer when using malaria RDTs and that the majority of them had used buffer substitutes, which are known to generate inaccurate tests results. This has the consequence of misdiagnosis, thus potentially damaging the credibility of malaria control. 1 results 1
- Background: A survey of perception of healthcare workers in a tertiary hospital [University College Hospital (UCH), Ibadan] was done with a view to determine the need to introduce a curriculum in wound care for healthcare workers. Materials and Methods: A self-administered questionnaire was used to capture data related to knowledge and practices on wound care from healthcare workers in UCH, Ibadan. Descriptive analysis was done using the Statistical Package for the Social Sciences version 21 software (SPSS Inc., Chicago, IL, USA). Results: One hundred and four healthcare professionals working in UCH, Ibadan, comprising doctors, nurses, and physiotherapist, with 61.1% over 10 years of experience in wound care were surveyed. Seventy- seven percent agree or strongly agree that healthcare professionals are knowledgeable about best practices in wound care. 50.5% agree or strongly agree that UCH operates best practices in wound care while 49% agree or strongly agree that wound assessment is standardized in the hospital. 96.2% agree or strongly agree that an interprofessional wound care course will be beneficial to healthcare professionals and that it will enable healthcare professionals speak the same language with regard to wounds. Conclusion: Teamwork and definite wound care policy/protocol are essential for excellent outcomes in wound care. Introduction of this approach will enhance knowledge translation and encourage best practice in our health institutions. 1 results 1
- Background: Effective prevention and control of malaria during pregnancy include prompt and effective case management of malaria combined with prevention of infection by the use of insecticide-treated nets and intermittent preventive treatment in pregnancy (IPTp). Care givers knowledge and practice of malaria control is pivotal to effective implementation of these guidelines. The objective of this study was to determine the awareness of care providers in facilities offering maternity services in Ibadan of the National Malaria Treatment Guideline and Policy in Nigeria. The study also aimed to describe the prescription practice, for malaria chemoprophylaxis and case management in pregnancy, by these care providers. Materials and method: The study was a cross-sectional survey of the; lead care givers in all registered hospitals and maternity centres in Ibadan over one year (April 2008 to April 2009), using structured questionnaires. The list of the one hundred and thirty-two (132) registered centres was obtained from the State Ministry of Health. The lead care givers provided information, on their awareness of the new government policy and antimalarials believed to be effective and prescribed for malaria prevention and case management in pregnancy. Results: Over two thirds (84.2%) of the facilities were operated by either Medical Officers with only basic medical training or by Nurses/Mid wives. The modes of prevention most commonly reported as being effective were the use of insecticide spray, window nets and ITN. The drugs most commonly prescribed for chemoprophylaxis were sulphadoxine-pyrimethamine (SP) (65.2%), Proguanil (45.5%) and pyrimethamine (42.4%). The drugs most commonly prescribed for case management were ACIfe (66.7%), amodiaquine (59.8%) and artemether (47.7%). Quite a number of respondents were unsure of the frequency (81.8%) and timing (56.5%) of administration of sulphadoxine- pyrimethamine for prophylaxis. Conclusion: This study demonstrates awareness but lack of in-depth knowledge of control measures. Also, there is poor use of the recommended agent for IPT. The factors militating against the use of these preventive measures need to be urgently explored and addressed. 1 results 1
- Background: Gambling rates are increasing among adolescents in rural communities. Our study aimed to determine the prevalence, patterns, and factors associated with gambling disorders, among in-school adolescents in a rural community in South-western Nigeria. Materials and methods: The study was crosssectional in design involving 427 adolescents selected by a two-stage sampling method across secondary schools in Igbo-Ora. A questionnaire developed from literature and “The South Oaks Gambling Screen-Revised Adolescent Questionnaire” was used to obtain information on sociodemographic and behavioural characteristics and gambling practices. Results: The mean age of the respondents was 14.0 ± 2.2 years with a little over half (51.3%) in the mid to older adolescent age group (14-17 years). The most common forms of gambling reported were playing dice games (46.0%), throwing rubber bands (42.5%), and card games (41.6%) for money. The odds of males ever gambling were two times more than females gambling (OR=2.43, 95%CI: 1.54-3.83). Conclusion: Gambling and problem gambling among adolescents in rural areas is high. Males and adolescents who use alcohol tend to gamble more. Multi-pronged interventions through education, youth-friendly programmes which will complement cultural values are recommended. There’s also a need to inculcate rehabilitation services at primary health care facilities in rural areas to manage adolescents who are problem gamblers. 1 results 1
- Background: Globally pregnancy and childbirth complications are the leading cause of death among adolescents, with evidence showing that antenatal care (ANC) is a very effective preventive intervention. In Burundi, there is limited information on the extent to which pregnant adolescents utilise such services. Objective: To assess the ANC utilisation and factors associated with its use among adolescent mothers in Ngozi Province, Burundi. Materials and Methods: A cross-sectional, health facility-based study among 216 adolescent mothers who had given birth within two years preceding this study, using structured questionnaires and records from previous ANC booklets. A multistage random sampling technique was used to select respondents while the utilisation of ANC was determined by the frequency of ANC visits and the time when the women enrolled for the first ANC visit. Results: The majority (98.1%) of adolescent mothers in Ngozi Province used ANC services. Most respondents (64.8%) initiated ANC services within the first trimester while 57.8% attained the minimum of four recommended ANC visits. Marital status (P = 0.001), geographical location (P = 0.009), occupation of the partner (P = 0.002) and type of the last pregnancy (P = 0.012) were associated with ANC initiation within the first trimester while marital status (P < 0.001), respondent’s employment (P = 0.003) and type of last pregnancy (P < 0.001) were associated with appropriate ANC frequency. Conclusion: This study revealed a high use of ANC services among adolescent mothers, although more than one-third attended ANC late. There is therefore the need to put more effort into improving early booking for ANC. 1 results 1
- Background: Head and neck cancer (HNC) is a major clinical and public health concern worldwide which impairs the vital functions of life. The treatment of metastatic HNCs is mainly palliative. This study examined the survival patterns and treatment outcomes in patients with HNCs in a tertiary hospital in Nigeria. Materials and methods: A review of the case files and treatment cards of patients with histological diagnosis of HNCs seen between January 2002 and December 2011 at the Radiotherapy Department, University College Hospital, Ibadan, was conducted. A total of 494 cases were identified, of which 481 had valid records. Analyses were done using Kaplan–Meier survival function and Cox proportional hazard regression techniques at 5% significance level. Results: The median age of patients was 42 years with a male-to-female ratio of 2:1. Most patients presented at stages 3 (50.7%) and 4 (36.8%). Nasopharyngeal carcinoma was the most common (42.6%) HNC, followed by paranasal sinus (17.7%) and laryngeal cancer (11.6%). The lung was the most common site of metastasis (25.5%). Patients who presented at stages 1 and 4 diseases had a median survival of 7.8 years and 1.9 years, respectively. Patients treated with a combination of chemotherapy and radiotherapy had a median survival of 8.0 years compared with those who had a single modality of treatment (~6.3 years). Conclusion: Patient survival was inversely proportional to the stage of the disease. To encourage the early presentation of HNC cases, health education of the population on routine medical check-ups and on the symptoms suggestive of HNC is recommended. Health care providers should be trained to refer suspected cases promptly to tertiary health facilities for management. 1 results 1
- Background: Malaria in pregnancy remains a significant cause of feto‑maternal morbidity and mortality especially in regions of high prevalence like Nigeria. Intermittent preventive therapy (IPT) for malaria is an important measure to abate this menace. Aim: The aim is to determine the uptake and effectiveness of IPT in relation to the occurrence of malaria, despite the use of IPT in pregnancy. Patients, Materials and Methods: This was a cross‑sectional study conducted in UCH, Ibadan from October 1, to December 31, 2020. A total of 150 postpartum women were selected using the total sampling technique of all consenting participants. Structured questionnaires were used for data collection. Results: About 87.7% of the respondents took IPT in the index pregnancy. Of these, 15.4%, 50.8%, and 33.8% of participants took one, two, and three doses, respectively. The factors that determined intermittent preventive treatment for malaria in pregnancy (IPTp) uptake include occupation (P = 0.001), booking status (P = 0.002), antenatal care attendance (P = 0.001), and level of IPTp awareness (P = 0.002). About 48.0% of respondents indicated that they were treated for malaria in the index pregnancy. Meanwhile, only about 15.3% of those who took IPT were treated for malaria in pregnancy. It was found that the use of IPT (P = 0.03) and an increasing number of IPT doses used (P = 0.03) were associated with a reduction in the prevalence of malaria in pregnancy. Conclusion: The uptake of the current recommendation for IPT‑SP that stipulates the use of monthly doses of IPT till delivery with a target of a minimum of three doses was quite poor. There is therefore an urgent need for widespread awareness and implementation of the World Health Organization and national guidelines on prevention of malaria. The prevalence of malaria declined with the number of doses of IPT‑SP used by the respondents. This emphasizes the need for adequate dosing of IPT. 1 results 1
- Background: Pregnancy in sickle cell disease (SCD) patients is associated with increased risk of fetomaternal morbidity and mortality. With improvements in management, education, awareness, and nutrition, more patients with SCD are maximizing their reproductive potential. Objectives: This review examined the pattern of complications and obstetrics outcomes of patients with SCD in a tertiary health facility. Materials and Methods: A descriptive retrospective study of 106 pregnant SCD patients who delivered at the University College Hospital, Ibadan between 1st January 2008 and 31st December 2017. Information on their demographic, medical and obstetrics characteristics, complications and outcome were obtained from their case notes using a pre-designed proforma. Data were analyzed using SPSS version 23. Results: Of the 106 cases reviewed, 64 (60.38%) had sickle cell anaemia (haemoglobin SS), 39 (36.79%) had haemoglobin SC and 3 (2.83%) had haemoglobin CC. The mean maternal age was 29.6±4.7 years. Majority, 83(78.3%), booked for antenatal care at mean gestational age (GA) of 19.4±8.7 weeks while the mean GA at delivery was 39.0±1.73 weeks. Bone pain crisis (38.8%) was the commonest non-obstetrics complication with 63.2% occurring among the HBSS genotype. The common obstetrics complications were preterm contraction, intrauterine fetal death (IUFD), and preeclampsia (each occurring among 27.3%). Overall, there were 84.9% live births and the overall fetomaternal outcome was satisfactory in 38.7%. Conclusion: Sickle cell disease in pregnancy has remained associated with increased risk of bone pain crises as well as preterm contractions, IUFD and preeclampsia. A multidisciplinary team approach is essential in ensuring a positive pregnancy outcome. 1 results 1
- Background: Sexual dysfunction is an important public‑health problem, which is often less reported or explored through opportunistic evaluation during medical consultations. Objective: This study was designed to determine the prevalence and patterns of female sexual dysfunction (FSD) including the sexual quality of life among female patients attending a gynecological outpatients unit in Southwest Nigeria. Materials and Methods: This is a cross‑sectional descriptive study of 146 consenting women who attended the gynecological outpatients’ clinic of the University College Hospital, Ibadan, Nigeria, during the study period. Participants were selected using multistage sampling technique. The survey instruments were previously validated questionnaires such as Sexual Function Questionnaire (SFQ28), Sexual Quality of Life‑Female Questionnaire (SQOL‑F), and the Family Adaptation, Partnership, Growth, Affection and Resolve (APGAR) score. The results were analyzed using Statistical Package for Social Sciences version 17 and P value was set at 5%. Results: The mean age was 33.8 ± 5.7 years. Most (85.6%) respondents had at least one form of sexual dysfunction. The commonest dysfunction was arousal‑sensation (62.4%) while the least was pain (3.4%). The mean SFQ28 and SQOL‑F scores were 58.0 ± 12.57 and 28.0 ± 11.94, respectively. There were no statistically significant differences in the SFQ28 and SQOL‑F scores across sociodemographic factors. Women classified as belonging to dysfunctional family on Family APGAR score similarly had poorer scores for sexual dysfunction (100%, P = 0.016). Conclusion: FSD is common among women attending gynecological outpatients clinic. Managing clinicians should be aware of this condition and proffer appropriate care in addition to the main presenting complaint. 1 results 1
- Background: Sickle cell disease (SCD) in pregnancy constitutes a high-risk pregnancy, associated with increased risk of adverse outcomes. Objective: To describe the outcome of pregnancy in SCD women managed at the University College Hospital, Ibadan, Nigeria. Materials and Methods: A retrospective review of the health records of sixty-three SCD pregnant women managed between January 1, 2016, and December 31, 2020. The information extracted included sociodemographic and obstetric characteristics, clinical presentations, mode of delivery, maternal and fetal outcomes. The data was analyzed using the IBM Statistical SPSS Statistics for Windows, version 23.0. The test of association was done using Chi-square and level of significance was p<0.05. Results: Prevalence of SCD in pregnant women was 0.65%. Mean age was 28.8±4.1years, 63.5% were haemoglobin SS while 36.5% were haemoglobin SC. Most of the women had tertiary education (61.8%) and booked for antenatal care (ANC) (60%). About 72.4% delivered at term while 46.1% had caesarean delivery. Most common complication was anaemia (79.4%) while vaso-occlusive crisis was the most common type of crisis (55.6%). Most of the women (92.5%) had live-birth with 15.2% of neonates requiring Neonatal Intensive Care Unit (NICU) admission. Maternal death rate was 6.3%. Good maternal and fetal outcomes occurred in 71.4% and 61.9% of participants respectively. Good maternal outcome was significantly associated with tertiary education(p=0.01). Good fetal outcome was associated with tertiary level of education(p=0.04) and multigravida status(p=0.03). Conclusion: SCD pregnant women have good fetal-maternal outcomes, however not receiving ANC and lower level of education were associated with poor pregnancy outcomes. Health education, access to ANC, prompt diagnosis, treatment of complications and multi-disciplinary team management will improve the pregnancy outcomes. 1 results 1
- Background: The elimination of hepatitis B virus (HBV) in Nigeria, especially among pregnant women requires commitment from the government and health policy makers. This is predicated on comprehensive surveillance and epidemiological data. The objective of the current study is to provide the epidemiological data and unique perspectives that will inform accurate advocacy and influence policy decisions. Materials and Methods: A 4-year cross-sectional study was conducted among 2,428 consecutively recruited consenting pregnant women attending antenatal care at the University College Hospital, Ibadan, Oyo State, Nigeria. Venous blood was screened for HBsAg using Enzyme Linked Immunosorbent Assay (ELISA). HBsAg sero-negative samples were further tested for other HBV serological markers (anti-HBc, HBeAg and anti-HBe by ELISA. Socio-demographic and clinical details were obtained using a semi-structured questionnaire. Results: Overall HBsAg prevalence was 5.1% (2,305/2,482). Twenty three (1%) of the HBsAg sero-negative women tested positive to both anti-HBc and anti-HBe while 5.3% and 0.8% tested positive to only anti-HBc and anti-HBe, respectively. Additionally, 6.4% (38/594) of the HBV fully vaccinated pregnant women tested positive to HBsAg. Conclusion: Hepatitis B is endemic among Nigerian pregnant women. Serological patterns indicated possible occult hepatitis B infection. More political commitment from government and policy makers is urgently required. 1 results 1
- Background: Traditional and faith healers constitute an important group of complementary and alternative mental health service providers (CAPs) in sub-Sahara Africa. Governments in the region commonly express a desire to integrate them into the public health system. The aim of the study was to describe the profile, practices and distribution of traditional and faith healers in three sub-Saharan African countries in great need for major improvements in their mental health systems namely Ghana, Kenya and Nigeria. Materials and methods: A mapping exercise of CAPs who provide mental health care was conducted in selected catchment areas in the three countries through a combination of desk review of existing registers, engagement activities with community leaders and a snowballing technique. Information was collected on the type of practice, the methods of diagnosis and the forms of treatment using a specially designed proforma. Results: We identified 205 CAPs in Ghana, 406 in Kenya and 82 in Nigeria. Most (> 70%) of the CAPs treat both physical and mental illnesses. CAPs receive training through long years of apprenticeship. They use a combination of herbs, various forms of divination and rituals in the treatment of mental disorders. The use of physical restraints by CAPs to manage patients was relatively uncommon in Kenya (4%) compared to Nigeria (63.4%) and Ghana (21%). CAPs often have between 2- to 10-fold capacity for patient admission compared to conventional mental health facilities. The profile of CAPs in Kenya stands out from those of Ghana and Nigeria in many respects. Conclusion: CAPs are an important group of providers of mental health care in sub-Saharan Africa, but attempts to integrate them into the public health system must address the common use of harmful treatment practices. 1 results 1
- Background: Turnaround time (TAT) analysis is finding increasing relevance in clinical laboratories due to its relevance in the quality of care of patients. TAT involves all the various processes that occur within the laboratory. Aims: The aim of this study was to analyze the histopathology TAT of surgical biopsies at the Department of Pathology, University College Hospital (UCH), Ibadan. Materials and Methods: This was a retrospective analysis of 1085 samples received at the Department of Pathology, UCH, Ibadan, from January to April 2020. Samples were categorized into small, intermediate, and large sizes. Average duration spent in the grossing room, processing, reporting, and result verification was calculated, and the total TAT was determined from the summation of the duration of these processes. Results: The mean TAT for all samples was 22 days(±10 days). Reception grossing, histological processing, reporting, and transcription accounted for an average of 1.5 (7%), 5.9 (27%), 9.1 (41%), and 5.6 (25%) days and percentage of TAT, respectively. There was no significant difference in the mean TATs for small , intermediate-, and large-sized samples. Conclusion: We identified reporting time as the largest contributor to TAT. Other areas of delay were noted at tissue processing and result verification. Adoption of new technology and staff orientation may help to reduce the observed TAT. 1 results 1
- Best practices 1 results 1
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