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THE SOCIAL COST OF FARMER-HERDER CONFLICTS IN ISEYIN,OYO STATE, NIGERIA
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POLLUTION STATUS AND CHEMICAL SPECIATION IN SURFACE WATER AND SEDIMENTS OF TWO RIVERS IN AKWA IBOM STATE, NIGERIA
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MOLECULAR AND ANTIGENIC CHARACTERISATION OF INFLUENZA VIRUSES ISOLATED FROM HORSES IN NIGERIA
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Urban Dynamics and Vulnerability to Disasters in Lagos State, Nigeria (1982 – 2012)
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Page will reload when a filter is selected or excluded.- "Students/performance in secondary schools in recent time have been below the expected standard based on the reports of public examination bodies (WAEC and NECO). Most often time teachers are blamed for this occurrence which suggests that job performance of teachers has been below the standard. This study therefore investigated teachers/ characteristics and welfare package as predictors of job performance among secondary school teachers in Ibadan Metropolis. The research design used in the study was survey, one hundred (100) teachers and three hundred (300) students were drawn through multistage sampling techniques from five local governments within Ibadan metropolis Four research instruments were used to collect data and four research questions were raised and answered in this study. The data obtained were analyzed using multiple regressions and descriptive statistics. The result show positive relationship between welfare package and teachers' job performance (R=.851, multiple R square of. 725 with Adjusted R square of .621).Moreover, the welfare package explains 62% of the variance observed in teachers/job performance. The observed variance was statistically significant at F (df =5, 17) = 7.015, p<0.05. Likewise, the findings show positive relationship between teachers' characteristics and teachers'job performance (R=.627, a multiple R square of.393 with Adjusted R square of.234 and teachers' characteristics accounted for 23% of the variance observed in teachers'job performance. The observed variance was statistically significant at F (df =6, 23) =2.479, p>O.05 The eleven components of the welfare package and teachers' characteristics jointly considered accounted for 73% of the observed variance in teachers/job performance and statistically significant at F (df =12, 10) = 5.983, p< 0.05. Based on the findings of the study, it was observed that there are positive relationships between welfare package, teachers characteristics and teachers' job performance. Therefore, when teachers possess good characteristics (in terms of qualification and teaching teachers possess good characteristics (in terms of qualification and teaching experience) and government increases teachers' welfare package this will directly enhance job performance among the teachers. It is therefore, recommended that government should encourage teachers to put in their best and develop positive attitude towards teaching by improving on the welfare packages for teachers andprompt payment of salary." 1 results 1
- A nationwide equine influenza virus surveillance was carried out between January 1989 and January 1995 during which nasopharyngeal swabs, tracheal washes and respiratory tract tissue homogenates were obtained from symptomatic and asymptomatic equine species in various parts of Nigeria for virus isolation and characterisation. Three equine influenza viruses were independently isolated in 10-11 day old embryonated hen eggs and Madin Darby canine kidney monolayer cells with TPCK-trypsin incorporated into the culture medium. The virus isolates were characterized antigenically, immunogenically and genetically which made them the first equine influenza viruses isolated and characterized in tropical Africa. Antigenic analyses with mono-specific antisera raised against a number of respiratory disease viruses including Paramyxoviruses, Adenoviruses, Herpes viruses, Alphavirus, Rhinoviruses, Equine arteritis viruses, African horse sickness viruses and Influenza viruses showed that the three virus isolates were influenza A viruses while haemagglutination and neuraminidase inhibition assays using influenza virus specific Mabs and polyclonal antisera showed the three viruses to be antigenically H3N8, members of equine-2 subtype of influenza A viruses. The three isolates were respectively named A/Equine/Ibadan/4/91, A/Equine/Ibadan/6/91 and A/Equine/Ibadan/9/91 in accordance with the recommendations of the World Health Organisation and the International Committee on Virus Taxonomy. Their antigenic cross-reactivity with panels of Mabs and polyclonal antisera indicated that the three viruses were antigenically divergent although they were all H3N8 viruses and were representatives of a homogenous population. They were reactive with Mabs and antisera directed against H3 equine viruses isolated in 1963, 1976, 1979, 1981 and 1986. This broad reactivity suggested that these isolates were similar to but not still different from those isolated in Europe and USA between 1963 and 1987. Virus protein synthesis and cleavability of the HA polypeptide in tissue culture were investigated by pulse-chase experiments. The results showed some heterogeneity in the non-glycosylated polypeptides particularly those of the ribonucleoprotein (RNP) complex while the HA glycoproteins of the three viruses were not cleaved in any of the cell types used in contrast to equine H7 and pathogenic avian H5 and H7 HAs. The molecular weights of the polypeptides were within the range previously determined for influenza A viruses. The heterogeneity of the RNP complex and antigenic divergence of the viruses’ HAs were confirmed by sequence analysis carried out in molecular studies. Virus infectivity was investigated by plaque assay using chicken embryo fibroblast (CEF) monolayer cells and virus titration in embryonated hen eggs. The results showed that the viruses were infectious with plaguing efficiency being comparable to efficiency of virus infectivity in embryonated hen eggs. Infectivity, antigenicity and immunogenicity of the three viruses were confirmed in-vitro using peripheral blood lymphocytes in lymphoproliferation assays and in-vivo in an equine model in which the viruses induced haemagglutination inhibiting and protective neutralising antibodies following experimental infections. The proliferating cells were also characterised and the immunoglobulin isotypes produced were determined. Molecular characterisation and genetic analyses of the three viruses were accomplished to determine the origin of the genes encoding the virus non-glycosylated polypeptides as well as those of the surface HA glycoprotein. Reverse transcription (RT) results showed the eight RNA segments of the three isolates and confirmed them as influenza A virus RNAs. No subgenomic RNAs or defective interfering particles were observed in the RNA transcripts. Nucleotide sequence analyses were carried out using three sequencing strategies of cDNA, vRNA and plasmid DNA sequencing with the dideoxy chain termination procedure. Partial nucleotide sequences were obtained from cDNAs, vRNAs and plasmid DNA clones of RNA segments 1, 2, 3, 5, 7 and 8 with the method of multiplex RT/PCR and cycle sequencing using radiolabelled segment specific oigonucleotides of 18, 24 or 25 mers. Complete nucleotide sequences of segment 4 (HA genes) were also determined on the same PCR products (cDNA) and vRNA using end-labelled oligonucleotides of both plus and minus sense. The partial nucleotide sequence data were analysed using a programme for "best-local-homology- rapid-search" on a digital array processor while the complete HA nucleotide and deduced amino acid sequence analyses were carried out using the University of Wisconsin Genetics Computer Group (GCG) package of programmes. Phytogenetic analysis was done with the distances, neighbour joining and DNAPARS of the PHYLIP package. Analyses of the viruses’ gene sequences confirmed that their genomes were similar to each other and to those of other H3N8 influenza viruses isolated from equines and also revealed the origin, evolution and genetic relatedness of the genes. Comparison of the partial cDNA sequences with virus DNA sequences in the database (EMBL sequence library) showed that for segments 1, 2, 5, and 7, the closest related sequences were from equine H3 viruses isolated in 1986 in USA (Tennesse/5/86 for segments 2, 5 and 7, Kentucky/2/86 for segments 1 and 5. Segment 5 was equally related to both viruses). The nucleotide sequence for segment 3 was most closely related to an equine-1 virus isolated in U.K. in 1973 (London/1416/73, H7N7) probably due to genetic exchange while segment 8 sequence was most closely related to an equine H3N8 virus isolated in U.K. in 1976 (Newmarket/76). The complete nucleotide and deduced amino acid sequences as well as phytogenetic analysis of the HA genes (RNA segment 4) showed a closer relationship albeit with nucleotide and amino acid substitutions between the three Ibadan viruses and those that were isolated in Europe in 1989 and 1991, the prototypic European strain, Suffolk/89 and Arundel/12369/91 isolated in U.K., Taby/91 isolated in Sweden, Hong Kong/92 isolated in the Far East in 1992 and Laplata/1/93 isolated in South America. These findings group the Ibadan viruses with those predominating and contemporarily causing disease in the Western Hemisphere rather than with viruses previously isolated from the north and south of African continent. Variation was observed in the nucleotide sequences of the Ibadan viruses HA genes. Some of the base changes resulted in amino acid changes which mapped to antigenic sites or within signal sequence in the HA1 domain as a result of a process of antigenic or genetic drift. The Ibadan viruses also showed some variation from the prototypic European virus (Suffolk/89) and these base changes also resulted in amino acid changes resulting in antigenic drift. Phytogenetic analysis showed the evolutionary lineages in equine H3 viruses isolated since 1963 along two paths one of which included the Ibadan viruses as well as viruses isolated in Europe between 1989 and 1991 and the Far East in 1992 and S. America in 1993 which form the 1989/93 cluster while the other lineage included viruses isolated in South America in 1987 and 1988 (Brazil/87, Laplata/88) and in the Far East in 1971 (Tokyo/3/71) all of which are very close to the original prototype equine-2 virus (Miami/63). These results demonstrate a faster evolutionary rate for recent equine H3 HA genes away from the original prototype virus. Overall, the results of these studies have (i) confirmed the occurrence of equine-2 H3N8 influenza viruses of distinct lineages in Nigerian equine populations in a tropical environment (ii) indicated antigenic drift among equine H3N8 viruses as earlier reported and confirmed that drift strains can co-circulate in equine populations, (iii) showed the origin, evolution and genetic relatedness of the viruses genes as well as their biological characteristics, (iv) provided the hitherto unavailable information on the status of equine influenza virus in this part of the world and (v) served to re-emphasise the potential of influenza virus for rapid global spread and the need for better control strategies. 1 results 1
- A study was carried out on the assessment of lead and cadmium in the eggs of Gallus gallus in Agbowo and Oluyole area of Ibadan. The aims and objectives of the study were to assess the level of lead (Pb) and cadmium (Cd), study the relationship between lead and cadmium, study the trend of lead and cadmium levels and estimate the health risk in consuming the eggs. Egg samples were collected randomly and fortnightly between July to September 2013 as rainy season and January to February 2014 as representing dry season. Eggs were acid-digested after weighing out 0.5g using weighing balance. Digested egg parts were then transferred to the Buck Scientific's 210VGP Atomic Absorption Spectrophotometer (AAS) for heavy metal analyses of lead and cadmium. Results show that the mean metal concentration in the eggs were in the order for Pb as: Egg yolk<egg white<egg shell, while Cd was egg yolk<egg shell<egg white in the month of July 2013 in Oluyole, while in Agbowo for the same month was Cd: Egg yolk<egg white<egg shell, while Pb was egg white<egg yolk<egg shell. Similar trends were observable with slight variations for other months and locations, but with the egg shell usually having a higher mean concentration for both metals. The mean seasonal pattern of variation in the heavy metals in the egg parts showed that lead was higher for both seasons than cadmium throughout the study. The rainy season values for cadmium and lead were lower than that of the dry season in both Agbowo and Oluyole areas of Ibadan. In Oluyole, Cd was higher during the rainy season (0.1156ppm) than during the dry season (0.1022ppm) with a similar pattern repeating itself for Pb in the egg shell from Oluyole area. The target hazard quotient (THQ) used for assessing health risk exceeded 1 for both lead and cadmium in the eggs thereby indicating a potential health risk associated with the metals. There was correlation between the occurrence of lead and cadmium in the eggs for all the months and locations thereby indicating a relationship between the two metals. The study shows that eggs supplied in parts of Ibadan are impacted by heavy metals such as lead and cadmium with potential health consequences that needs to further investigated 1 results 1
- Acute Incidence 1 results 1
- Acute stroke 1 results 1
- African 1 results 1
- African feminist literary texts most often document that patterns of intimate partner violence are as a result of socio-culturally imposed structuration in the hierarchy of the sexes, due to cultural determinisms. Hence, it is in most cases assumed that only, women are victims of intimate male partner violence. There are growing concerns that men may just be as well victims of intimate female perpetrated violence. This research investigates roles of female body and sexuality in perpetrating violence against men for the purpose of subverting masculine power in two selected plays from Isaie Biton Koulibaly's anthology, Encore les femmes ... toujours les femmes! The concept of bodiliness is used to investigate the amount of power the female body is able to deploy in quest for female emancipation. The research finds that radical females in the selected short stories deploy powers resident in the body and non-normative sexuality practices to script a new trend of shift in the occurrence and performance of gender violence in intimate relationships. The subversion of hegemony and relegation of male characters is contingent upon the resoluteness of the female characters to use their bodies and sexuality as weapons to undo prescribed gender norms.. 1 results 1
- All over the world, social communication and interaction are fundamental aspects of everyday life. From infancy, humans are social beings, gazing at other people and turning towards voices, grasp a finger and even smiles. For social relationship to become possible there is a need to take into consideration the thoughts and feelings of another person. Essentially, it is the understanding that others' thought is different from one's thought that makes social interaction possible. However, some children experience difficulties with successful social communication and this inability or deficit is termed social communication disorder (SCD). This impaired social language use creates communication difficulties, thereby causing significant impact on academic, adaptive and psychosocial functioning. Additionally, children with SCD has been under identified over time due to its co-occurrence with other conditions which leads to wrong diagnosis, inappropriate therapeutic considerations and non-effective communication as well as poor interpersonal relationship. Thus, this paper, focuses on the causes, incidence, assessment, impact and therapeutic interventions of social communication disorder. 1 results 1
- Anion Gap 1 results 1
- Aquifers 1 results 1
- Background – It is unclear whether a natural marker of atherosclerosis (carotid intima-media thickness: CIMT) or calculated risk score is more associated with stroke. We therefore comparatively examined the relationship between CIMT as well as two cardiovascular risk calculators (Omnibus Risk Score -ORS and Framingham Risk Score- FRS) and the occurrence of stroke among hypertensive African patients. Methods – CIMT was measured in 555 consecutive consenting hypertensive adults (377 stroke patients and 178 strokefree subjects). The 10-year cardiovascular risk was calculated for each participant with the FRS and ORS. The strengths of association between FRS, ORS, CIMT, and stroke occurrence were examined using logistic regression. The discriminative capacity of FRS, ORS, and CIMT for stroke occurrence was assessed with c-statistics. Results – Higher average CIMT (OR 11.71; 95% CI 1.65–83.07; P = 0.01) was strongly associated with stroke after adjusting for age, sex, blood pressure, serum cholesterol, and blood sugar. Neither the FRS (OR: 1.03; CI: 0.89–1.19, P = 0.68) nor the ORS (OR: 1.08; CI: 0.90–1.30; P = 0.41) was significantly associated with stroke. CIMT had a higher c-statistic for differentiating stroke patients from hypertensive controls (right: c = 0.63, P < 0.001; left: c = 0.67, P < 0.001; average: c = 0.66, P < 0.001) than some conventional risk factors. Neither FRS (P = 0.39) nor ORS (P = 0.55) was able to independently differentiate between stroke and hypertensive patients. Conclusion – CIMT, but neither FRS nor ORS, is independently associated with stroke among Nigerian African hypertensive patients. CIMT may be a better tool for estimating the overall risk of stroke than FRS or ORS in this population. 1 results 1
- Background: Africa has a growing burden of stroke with associated high morbidity and a 3-year fatality rate of 84%. Cardiac disease contributes to stroke occurrence and outcomes, but the precise relationship of abnormalities as noted on a cheap and widely available test, the electrocardiogram (ECG), and acute stroke out comes have not been previously characterized in Africans. Objectives: The study assessed the prevalence and prognoses of various ECG abnormalities among African acute stroke patients encountered in a multisite, cross-national epidemiologic study. Methods: We included 890 patients from Nigeria and Ghana with acute stroke who had 12-lead ECG recording within first 24 h of admission and stroke classified based on brain computed tomography scan or magnetic resonance imaging. Stroke severity at baseline was assessed using the Stroke Levity Scale (SLS), whereas 1-month outcome was assessed using the modified Rankin Scale (mRS). Results: Patients’ mean age was 58.4 13.4 years, 490 were men (55%) and 400 were women (45%), 65.5% had ischemic stroke, and 85.4% had at least 1 ECG abnormality. Women were significantly more likely to have atrial fibrillation, or left ventricular hypertrophy with or without strain pattern. Compared to ischemic stroke patients, hemorrhagic stroke patients were less likely to have atrial fibrillation (1.0% vs. 6.7%; p ¼ 0.002), but more likely to have left ventricular hypertrophy (64.4% vs. 51.4%; p ¼ 0.004). Odds of severe disability or death at 1 month were higher with severe stroke (AOR: 2.25; 95% confidence interval: 1.44 to 3.50), or atrial enlargement (AOR: 1.45; 95% confidence interval: 1.04 to 2.02). Conclusions: About 4 in 5 acute stroke patients in this African cohort had evidence of a baseline ECG abnormality, but presence of any atrial enlargement was the only independent ECG predictor of death or disability 1 results 1
- Background: Metabolic acidosis (MA) still remains a very common finding in patients with end stage kidney disease (ESRD) despite the increasing volume of research on dialysis treatment that have resulted in improved haemodialysis delivery. Its occurrence increases the risk of dialysis termination and inadequate dialysis dose that is associated with poor treatment outcome. The study endeavored to study metabolic acidosis and to determine its relationship with the dialysis dose (Kt/V). Materials and Methods: This was a two centre cross-sectional study involving 298 participants with ESKD who had 1642 sessions of maintenance haemodialysis. Serum electrolytes were analyzed by the Ion-Selective Electrode method and haematocrit was determined using a Hematocrit Centrifuge Results: Two hundred and ninety eight (192 males and 106 females) participants took part with a mean age of 51.44 + 7.31 years (males, 51.18 + 4.62 years, females, 52.14 + 2.93 years), P=0.04. The mean serum bicarbonate concentration, post dialysis (20.61 ± 6.26 mmol/L) was significantly higher than the pre dialysis, 18.41 ± 3.63 mmol/L (P<0.001) concentration. The prevalence of pre and post dialysis metabolic acidosis were 79.0% and 38.3% (P<0.001) There was a significant reduction in the mean anion gap following dialysis (P<0.001). The mean dialysis dose was significantly higher in males than females (P=0.03) and in participants with normal PSBC than participants with low PSBC (P<0.001) Risk factors for metabolic acidosis were advancing age, elevated Body Mass Index and blood pressure. Metabolic acidosis was negatively related to glomerular filtration rate and haematocrit. Aging, lesser dialysis frequency, independently predicted metabolic acidosis Conclusion: Metabolic acidosis is quite common in patients on maintenance dialysis, more common in females, advancing age and in less frequent dialysis treatment. Its occurrence increased the risk of inadequate dialysis. 1 results 1
- Blood protein polymorphism 1 results 1
- Bodiliness 1 results 1
- Burden 1 results 1
- Butterflies are considered as good ecological indicators for other invertebrate and as surrogate representatives of environmental quality changes. Their occurrence and diversity in populations contribute to thriving ecosystems and can indicate the state of an ecosystem’s health. Though, there is high increase in habitat fragmentation of most protected area. However, information on butterfly species abundance, richness on different habitat is limited in the study area. The study assessed the diversity and abundance butterfly species in relation to its environmental factors. Sampling was done quantitatively using three complementary methods, line transect (walk-and-counts), hand nets, and fruit bait traps in June and July 2018. Data was analysed using descriptive statistics, diversity indices and Pearson’s correlation. A total of 646 individual representing 40 butterfly species belonging to 5 families in the order Lepidoptera were recorded across the three different habitats. Members of Nymphalidae family occurred most and accounted for 57.5% species and 63.3% total number of individual species with Acrsea serena been the most dominant across the habitats. Forest habitat had the highest species composition (n = 316). Generally, species abundance (31.0%), richness (33.7%) and family composition (33.7%) respectively, were recorded more through visual count method, while mean species abundance (26.1%) encountered higher with hand-net method. There was no significant relationship between the environmental factors and the total number of individuals or species richness. But rainfall was found to be positively correlated with the species diversity and abundance. Hence, understanding the factors affecting butterfly species diversity and abundance in IITA is very important for conservation purposes. 1 results 1
- Cellulose acetate electrophoresis 1 results 1
- Children health 1 results 1
- Conflict management 1 results 1
- Coping strategies 1 results 1
- Cross River (CR) andQua Iboe River (QIR) in AkwaIbom State are prone to pollution from diverse sources including urbanisation and agricultural activities. The state and national agencies are exploiting the river banks for establishing industrial and recreational parks. Due toscarcity of data on the pollution and human exposure risks of these rivers, there is need to establish their pollution status. This work was aimed at determining the physicochemical characteristics, metal speciation in surface water and sediments and saturation indices on these rivers. Surface water and sediment samples were collected monthly between June 2009 and May 2010 from six stations with high human activities along CR (Okopedi, Ayadehe, Nwaniba, Oron, James-Town, Ibaka) and QIR (Iwuokpom1, Iwuokpom2, Iwuochang, Eketai, Atabong, Marina). Sampling was done by compositing three grab samples from each station giving a total of 144 each of water and sediment samples. Selected pollution parameters and trace metal concentrations were determined using APHA methods. A thermodynamic model, pH-Redox-Equilibrium-Computer programming language-Interactive (PHREEQCI), was employed to determine some metal species and saturation indices of associated mineral phases in water samples. The relationship between metal speciation in water with sediment in terms of bioavailability was evaluated using the European Union Binding Corporate Rules reference method. Data were analysed using coefficient of variation and Pearson correlation at p = 0.05. The concentrations (mgL±1) of alkalinity (36.1±19.2, 61.3±35.1), dissolved oxygen (7.6±1.2, 6.4±0.9), nitrate (12.3±9.6, 4.6±2.9), chloride (880±520, 860±140), phosphate (0.05±0.02, 0.10±0.02) and sulphate (30.9±9.0, 36.2±6.6) in the rivers (Cross, Qua Iboe) respectively were obtained. The concentrations (mgL±1) of Cd(0.02±0.01, 0.04±0.05), Pb(0.02±0.01, 0.03±0.03), and Ni(0.05±0.05, 0.06±0.08) in water exceeded the WHO limits while those of Cr(0.02±0.02, 0.04±0.03), Cu(0.04±0.02, 0.07±0.07) and Zn(0.11±0.07, 0.20±0.09) were below the limits. Metal variability in water forCross River was higher for Cd (81.3%) and Ni (94.0%). There were strong correlations for Cr/Co (r=0.9), Cu/Co (r=0.9) and Ni/Co (r=0.8) indicating point source of metal pollution. The dominant metal species for the rivers were the free hydrated species of Co2+(97.0, 97.7%); Cu2+(82.8, 70.2%); Ni2+(98.1, 97.6%); Pb2+(60.0, 62.0%); CdCl+(82.2, 82.3%) and CrOH2+(53.1, 58.7%). The concentrations (�gg�1) of Cd, Pb, Ni, Cr, Cu, Zn and Co in sediments of Cross and Qua Iboe Rivers correspondingly were 0.50±0.24, 1.59±0.87; 59.3±14.2, 13.4±6.2; 6.60±2.3, 4.9±3.0; 15.9±5.3, 20.9±14.0; 71.8±17.3, 45.3±16; 129±12, 122±18; 7.60±2.3, 5.5±3.0. The non-residual sediment fraction of Cd, Pb and Cu in Cross and Qua Iboe Rivers were 89.3 and 88.7%, 62.4 and 64.0%, and 83.1 and 83.3% respectively. Saturation indices showed supersaturation for CdCr2O4, CuCr2O4, PbHPO4 and Pb-pyromorphite minerals. There was a dominance of bioavailable fractions bound to Fe/Mn-oxide and organic/sulphide components. Comparison with PHREEQCI data showed higher metal bioavailability in water than in the sediments. The metal pollution levels in the two rivers may be due to anthropogenic activities in the rivers. The occurrence of bioavailable metals suggests potential health risk from metal toxicities. 1 results 1
- Dialysis Dose 1 results 1
- Downy mildew| 1 results 1
- ECG abnormalities 1 results 1
- Earth Sciences 1 results 1
- Egg|| Lead|| Cadmium|| Gallus gallus|| Ibadan 1 results 1
- Entomology 1 results 1
- Environmental Management 1 results 1
- Environmental Sciences 1 results 1
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